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Submission guidelines

Contents

Instructions for Authors

General Information

The Journal of Digital Imaging (JDI) is the official peer-reviewed journal of the Society for Imaging Informatics in Medicine (SIIM). JDI's goal is to enhance the exchange of knowledge encompassed by the general topic of Imaging Informatics in Medicine including, but not limited to, research and practice in clinical, engineering, information technologies and techniques in all medical imaging environments.

Topics of interest to the readers of JDI include the following as they pertain to the acquisition, storage, retrieval and use of imaging information in healthcare to efficiently and effectively improve access and quality:

• PACS and component systems

• Imaging informatics for the enterprise

• Image-enabled electronic medical records

• Integrating mobile technologies

• RIS, HIS and other clinical information systems

• Digital image acquisition, transmission, storage, display and interpretation

• 3D (e.g. printing, modeling, display)

• SIIM Workflow Initiative in Medicine (SWIM)

• DICOM and other standards

• IHE

• Imaging vocabularies and ontologies

• Analytics

• Workflow and process modeling and simulation

• Protocolling and appropriateness

• Structured reporting

• Speech recognition

• Content-based image retrieval

• Meaningful use and legislative issues

• Decision support

• Radiation dose management

• Teleradiology

• Archiving and information lifecycle management

• Network integrity and data security

• Multimedia

• Facilities design

• Project management

• Quality assurance

• Online learning

• Imaging informatics education

Papers that report on validation and implementation of informatics technologies and tools will be given precedence over papers that simply describe image processing algorithms, stand-alone evaluation of image analysis tools, and/or technology descriptions without validation or implementation.

Please note: Revised manuscripts should be prepared with tracked-changes to clearly indicate all revisions made. Please upload only the tracked-changes version of the manuscript (a clean manuscript version is not required).

Ethical Responsibilities of Authors

This journal is committed to upholding the integrity of the scientific record. As a member of the Committee on Publication Ethics (COPE) the journal will follow the COPE guidelines on how to deal with potential acts of misconduct.

Authors should refrain from misrepresenting research results which could damage the trust in the journal, the professionalism of scientific authorship, and ultimately the entire scientific endeavour. Maintaining integrity of the research and its presentation is helped by following the rules of good scientific practice, which include*:

  • The manuscript should not be submitted to more than one journal for simultaneous consideration.
  • The submitted work should be original and should not have been published elsewhere in any form or language (partially or in full), unless the new work concerns an expansion of previous work. (Please provide transparency on the re-use of material to avoid the concerns about text-recycling (‘self-plagiarism’).
  • A single study should not be split up into several parts to increase the quantity of submissions and submitted to various journals or to one journal over time (i.e. ‘salami-slicing/publishing’).
  • Concurrent or secondary publication is sometimes justifiable, provided certain conditions are met. Examples include: translations or a manuscript that is intended for a different group of readers.
  • Results should be presented clearly, honestly, and without fabrication, falsification or inappropriate data manipulation (including image based manipulation). Authors should adhere to discipline-specific rules for acquiring, selecting and processing data.
  • No data, text, or theories by others are presented as if they were the author’s own (‘plagiarism’). Proper acknowledgements to other works must be given (this includes material that is closely copied (near verbatim), summarized and/or paraphrased), quotation marks (to indicate words taken from another source) are used for verbatim copying of material, and permissions secured for material that is copyrighted.

Important note: the journal may use software to screen for plagiarism.

  • Authors should make sure they have permissions for the use of software, questionnaires/(web) surveys and scales in their studies (if appropriate).
  • Research articles and non-research articles (e.g. Opinion, Review, and Commentary articles) must cite appropriate and relevant literature in support of the claims made. Excessive and inappropriate self-citation or coordinated efforts among several authors to collectively self-cite is strongly discouraged.
  • Authors should avoid untrue statements about an entity (who can be an individual person or a company) or descriptions of their behavior or actions that could potentially be seen as personal attacks or allegations about that person.
  • Research that may be misapplied to pose a threat to public health or national security should be clearly identified in the manuscript (e.g. dual use of research). Examples include creation of harmful consequences of biological agents or toxins, disruption of immunity of vaccines, unusual hazards in the use of chemicals, weaponization of research/technology (amongst others).
  • Authors are strongly advised to ensure the author group, the Corresponding Author, and the order of authors are all correct at submission. Adding and/or deleting authors during the revision stages is generally not permitted, but in some cases may be warranted. Reasons for changes in authorship should be explained in detail. Please note that changes to authorship cannot be made after acceptance of a manuscript.

*All of the above are guidelines and authors need to make sure to respect third parties rights such as copyright and/or moral rights.

Upon request authors should be prepared to send relevant documentation or data in order to verify the validity of the results presented. This could be in the form of raw data, samples, records, etc. Sensitive information in the form of confidential or proprietary data is excluded.

If there is suspicion of misbehavior or alleged fraud the Journal and/or Publisher will carry out an investigation following COPE guidelines. If, after investigation, there are valid concerns, the author(s) concerned will be contacted under their given e-mail address and given an opportunity to address the issue. Depending on the situation, this may result in the Journal’s and/or Publisher’s implementation of the following measures, including, but not limited to:

  • If the manuscript is still under consideration, it may be rejected and returned to the author.
  • If the article has already been published online, depending on the nature and severity of the infraction:

    - an erratum/correction may be placed with the article

    - an expression of concern may be placed with the article

    - or in severe cases retraction of the article may occur.

The reason will be given in the published erratum/correction, expression of concern or retraction note. Please note that retraction means that the article is maintained on the platform, watermarked “retracted” and the explanation for the retraction is provided in a note linked to the watermarked article.

  • The author’s institution may be informed
  • A notice of suspected transgression of ethical standards in the peer review system may be included as part of the author’s and article’s bibliographic record.

Fundamental errors

Authors have an obligation to correct mistakes once they discover a significant error or inaccuracy in their published article. The author(s) is/are requested to contact the journal and explain in what sense the error is impacting the article. A decision on how to correct the literature will depend on the nature of the error. This may be a correction or retraction. The retraction note should provide transparency which parts of the article are impacted by the error.

Suggesting / excluding reviewers

Authors are welcome to suggest suitable reviewers and/or request the exclusion of certain individuals when they submit their manuscripts. When suggesting reviewers, authors should make sure they are totally independent and not connected to the work in any way. It is strongly recommended to suggest a mix of reviewers from different countries and different institutions. When suggesting reviewers, the Corresponding Author must provide an institutional email address for each suggested reviewer, or, if this is not possible to include other means of verifying the identity such as a link to a personal homepage, a link to the publication record or a researcher or author ID in the submission letter. Please note that the Journal may not use the suggestions, but suggestions are appreciated and may help facilitate the peer review process.

Compliance with Ethical Standards

To ensure objectivity and transparency in research and to ensure that accepted principles of ethical and professional conduct have been followed, authors should include information regarding sources of funding, potential conflicts of interest (financial or non-financial), informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals.

Authors should include the following statements (if applicable) in a separate section entitled “Compliance with Ethical Standards” when submitting a paper:

  • Disclosure of potential conflicts of interest
  • Research involving Human Participants and/or Animals
  • Informed consent

Please note that standards could vary slightly per journal dependent on their peer review policies (i.e. single or double blind peer review) as well as per journal subject discipline. Before submitting your article check the instructions following this section carefully.

The corresponding author should be prepared to collect documentation of compliance with ethical standards and send if requested during peer review or after publication.

The Editors reserve the right to reject manuscripts that do not comply with the above-mentioned guidelines. The author will be held responsible for false statements or failure to fulfill the above-mentioned guidelines.

Conflict of Interest

Authors must disclose all relationships or interests that could influence or bias the work. Although an author may not feel there are conflicts, disclosure of relationships and interests affords a more transparent process, leading to an accurate and objective assessment of the work. Awareness of real or perceived conflicts of interests is a perspective to which the readers are entitled and is not meant to imply that a financial relationship with an organization that sponsored the research or compensation for consultancy work is inappropriate. Examples of potential conflicts of interests that are directly or indirectly related to the research may include but are not limited to the following:

• Research grants from funding agencies (please give the research funder and the grant number)

• Honoraria for speaking at symposia

• Financial support for attending symposia

• Financial support for educational programs

• Employment or consultation

• Support from a project sponsor

• Position on advisory board or board of directors or other type of management relationships

• Multiple affiliations

• Financial relationships, for example equity ownership or investment interest

• Intellectual property rights (e.g. patents, copyrights and royalties from such rights)

• Holdings of spouse and/or children that may have financial interest in the work

In addition, interests that go beyond financial interests and compensation (non-financial interests) that may be important to readers should be disclosed. These may include but are not limited to personal relationships or competing interests directly or indirectly tied to this research, or professional interests or personal beliefs that may influence your research.

The corresponding author collects the conflict of interest disclosure forms from all authors. In author collaborations where formal agreements for representation allow it, it is sufficient for the corresponding author to sign the disclosure form on behalf of all authors.

The corresponding author will include a summary statement on the title page that is separate from their manuscript, that reflects what is recorded in the potential conflict of interest disclosure form(s).

See below examples of disclosures:

• Funding: This study was funded by X (grant number X).

• Conflict of Interest: Author A has received research grants from Company A. Author B has received a speaker honorarium from Company X and owns stock in Company Y. Author C is a member of committee Z.

• If no conflict exists, the authors should state: Conflict of Interest: The authors declare that they have no conflict of interest.

ICMJE -Conflict of Interest form (Download pdf, 1.2 MB)

Research involving human participants, their data or biological material

Ethics approval

When reporting a study that involved human participants, their data or biological material, authors should include a statement that confirms that the study was approved (or granted exemption) by the appropriate institutional and/or national research ethics committee (including the name of the ethics committee) and certify that the study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. If doubt exists whether the research was conducted in accordance with the 1964 Helsinki Declaration or comparable standards, the authors must explain the reasons for their approach, and demonstrate that an independent ethics committee or institutional review board explicitly approved the doubtful aspects of the study. If a study was granted exemption from requiring ethics approval, this should also be detailed in the manuscript (including the reasons for the exemption).

Retrospective ethics approval

If a study has not been granted ethics committee approval prior to commencing, retrospective ethics approval usually cannot be obtained and it may not be possible to consider the manuscript for peer review. The decision on whether to proceed to peer review in such cases is at the Editor's discretion.

Ethics approval for retrospective studies

Although retrospective studies are conducted on already available data or biological material (for which formal consent may not be needed or is difficult to obtain) ethics approval may be required dependent on the law and the national ethical guidelines of a country. Authors should check with their institution to make sure they are complying with the specific requirements of their country.

Ethics approval for case studies

Case reports require ethics approval. Most institutions will have specific policies on this subject. Authors should check with their institution to make sure they are complying with the specific requirements of their institution and seek ethics approval where needed. Authors should be aware to secure informed consent from the individual (or parent or guardian if the participant is a minor or incapable) See also section on Informed Consent.

Cell lines

If human cells are used, authors must declare in the manuscript: what cell lines were used by describing the source of the cell line, including when and from where it was obtained, whether the cell line has recently been authenticated and by what method. If cells were bought from a life science company the following need to be given in the manuscript: name of company (that provided the cells), cell type, number of cell line, and batch of cells.

It is recommended that authors check the NCBI database for misidentification and contamination of human cell lines. This step will alert authors to possible problems with the cell line and may save considerable time and effort.

Further information is available from the International Cell Line Authentication Committee (ICLAC).

Authors should include a statement that confirms that an institutional or independent ethics committee (including the name of the ethics committee) approved the study and that informed consent was obtained from the donor or next of kin.

Research Resource Identifiers (RRID)

Research Resource Identifiers (RRID) are persistent unique identifiers (effectively similar to a DOI) for research resources. This journal encourages authors to adopt RRIDs when reporting key biological resources (antibodies, cell lines, model organisms and tools) in their manuscripts.

Examples:

Organism: Filip1tm1a(KOMP)Wtsi RRID:MMRRC_055641-UCD

Cell Line: RST307 cell line RRID:CVCL_C321

Antibody: Luciferase antibody DSHB Cat# LUC-3, RRID:AB_2722109

Plasmid: mRuby3 plasmid RRID:Addgene_104005

Software: ImageJ Version 1.2.4 RRID:SCR_003070

RRIDs are provided by the Resource Identification Portal. Many commonly used research resources already have designated RRIDs. The portal also provides authors links so that they can quickly register a new resource and obtain an RRID.

Clinical Trial Registration

The World Health Organization (WHO) definition of a clinical trial is "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". The WHO defines health interventions as “A health intervention is an act performed for, with or on behalf of a person or population whose purpose is to assess, improve, maintain, promote or modify health, functioning or health conditions” and a health-related outcome is generally defined as a change in the health of a person or population as a result of an intervention.

To ensure the integrity of the reporting of patient-centered trials, authors must register prospective clinical trials (phase II to IV trials) in suitable publicly available repositories. For example www.clinicaltrials.gov or any of the primary registries that participate in the WHO International Clinical Trials Registry Platform.

The trial registration number (TRN) and date of registration should be included as the last line of the manuscript abstract.

For clinical trials that have not been registered prospectively, authors are encouraged to register retrospectively to ensure the complete publication of all results. The trial registration number (TRN), date of registration and the words 'retrospectively registered’ should be included as the last line of the manuscript abstract.

Standards of reporting

Springer Nature advocates complete and transparent reporting of biomedical and biological research and research with biological applications. Authors are recommended to adhere to the minimum reporting guidelines hosted by the EQUATOR Network when preparing their manuscript.

Exact requirements may vary depending on the journal; please refer to the journal’s Instructions for Authors.

Checklists are available for a number of study designs, including:

Randomised trials (CONSORT) and Study protocols (SPIRIT)

Observational studies (STROBE)

Systematic reviews and meta-analyses (PRISMA) and protocols (Prisma-P)

Diagnostic/prognostic studies (STARD) and (TRIPOD)

Case reports (CARE)

Clinical practice guidelines (AGREE) and (RIGHT)

Qualitative research (SRQR) and (COREQ)

Animal pre-clinical studies (ARRIVE)

Quality improvement studies (SQUIRE)

Economic evaluations (CHEERS)

Summary of requirements

The above should be summarized in a statement and placed in a ‘Declarations’ section before the reference list under a heading of ‘Ethics approval’.

Examples of statements to be used when ethics approval has been obtained:

• All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the Bioethics Committee of the Medical University of A (No. ...).

• This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University B (Date.../No. ...).

• Approval was obtained from the ethics committee of University C. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

• The questionnaire and methodology for this study was approved by the Human Research Ethics committee of the University of D (Ethics approval number: ...).

Examples of statements to be used for a retrospective study:

• Ethical approval was waived by the local Ethics Committee of University A in view of the retrospective nature of the study and all the procedures being performed were part of the routine care.

• This research study was conducted retrospectively from data obtained for clinical purposes. We consulted extensively with the IRB of XYZ who determined that our study did not need ethical approval. An IRB official waiver of ethical approval was granted from the IRB of XYZ.

• This retrospective chart review study involving human participants was in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The Human Investigation Committee (IRB) of University B approved this study.

Examples of statements to be used when no ethical approval is required/exemption granted:

• This is an observational study. The XYZ Research Ethics Committee has confirmed that no ethical approval is required.

• The data reproduced from Article X utilized human tissue that was procured via our Biobank AB, which provides de-identified samples. This study was reviewed and deemed exempt by our XYZ Institutional Review Board. The BioBank protocols are in accordance with the ethical standards of our institution and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Authors are responsible for correctness of the statements provided in the manuscript. See also Authorship Principles. The Editor-in-Chief reserves the right to reject submissions that do not meet the guidelines described in this section.

All individuals have individual rights that are not to be infringed. Individual participants in studies have, for example, the right to decide what happens to the (identifiable) personal data gathered, to what they have said during a study or an interview, as well as to any photograph that was taken. This is especially true concerning images of vulnerable people (e.g. minors, patients, refugees, etc) or the use of images in sensitive contexts. In many instances authors will need to secure written consent before including images.

Identifying details (names, dates of birth, identity numbers, biometrical characteristics (such as facial features, fingerprint, writing style, voice pattern, DNA or other distinguishing characteristic) and other information) of the participants that were studied should not be published in written descriptions, photographs, and genetic profiles unless the information is essential for scholarly purposes and the participant (or parent/guardian if the participant is a minor or incapable or legal representative) gave written informed consent for publication. Complete anonymity is difficult to achieve in some cases. Detailed descriptions of individual participants, whether of their whole bodies or of body sections, may lead to disclosure of their identity. Under certain circumstances consent is not required as long as information is anonymized and the submission does not include images that may identify the person.

Informed consent for publication should be obtained if there is any doubt. For example, masking the eye region in photographs of participants is inadequate protection of anonymity. If identifying characteristics are altered to protect anonymity, such as in genetic profiles, authors should provide assurance that alterations do not distort meaning.

Exceptions where it is not necessary to obtain consent:

• Images such as x rays, laparoscopic images, ultrasound images, brain scans, pathology slides unless there is a concern about identifying information in which case, authors should ensure that consent is obtained.

• Reuse of images: If images are being reused from prior publications, the Publisher will assume that the prior publication obtained the relevant information regarding consent. Authors should provide the appropriate attribution for republished images.

Consent and already available data and/or biologic material

Regardless of whether material is collected from living or dead patients, they (family or guardian if the deceased has not made a pre-mortem decision) must have given prior written consent. The aspect of confidentiality as well as any wishes from the deceased should be respected.

Data protection, confidentiality and privacy

When biological material is donated for or data is generated as part of a research project authors should ensure, as part of the informed consent procedure, that the participants are made aware what kind of (personal) data will be processed, how it will be used and for what purpose. In case of data acquired via a biobank/biorepository, it is possible they apply a broad consent which allows research participants to consent to a broad range of uses of their data and samples which is regarded by research ethics committees as specific enough to be considered “informed”. However, authors should always check the specific biobank/biorepository policies or any other type of data provider policies (in case of non-bio research) to be sure that this is the case.

Consent to Participate

For all research involving human subjects, freely-given, informed consent to participate in the study must be obtained from participants (or their parent or legal guardian in the case of children under 16) and a statement to this effect should appear in the manuscript. In the case of articles describing human transplantation studies, authors must include a statement declaring that no organs/tissues were obtained from prisoners and must also name the institution(s)/clinic(s)/department(s) via which organs/tissues were obtained. For manuscripts reporting studies involving vulnerable groups where there is the potential for coercion or where consent may not have been fully informed, extra care will be taken by the editor and may be referred to the Springer Nature Research Integrity Group.

Consent to Publish

Individuals may consent to participate in a study, but object to having their data published in a journal article. Authors should make sure to also seek consent from individuals to publish their data prior to submitting their paper to a journal. This is in particular applicable to case studies. A consent to publish form can be found

here. (Download docx, 36 kB)

Summary of requirements

The above should be summarized in a statement and placed in a ‘Declarations’ section before the reference list under a heading of ‘Consent to participate’ and/or ‘Consent to publish’. Other declarations include Funding, Competing interests, Ethics approval, Consent, Data and/or Code availability and Authors’ contribution statements.

Please see the various examples of wording below and revise/customize the sample statements according to your own needs.

Sample statements for "Consent to participate":

Informed consent was obtained from all individual participants included in the study.

Informed consent was obtained from legal guardians.

Written informed consent was obtained from the parents.

Verbal informed consent was obtained prior to the interview.

Sample statements for “Consent to publish”:

The authors affirm that human research participants provided informed consent for publication of the images in Figure(s) 1a, 1b and 1c.

The participant has consented to the submission of the case report to the journal.

Patients signed informed consent regarding publishing their data and photographs.

Sample statements if identifying information about participants is available in the article:

Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.

Authors are responsible for correctness of the statements provided in the manuscript. See also Authorship Principles. The Editor-in-Chief reserves the right to reject submissions that do not meet the guidelines described in this section.

Images will be removed from publication if authors have not obtained informed consent or the paper may be removed and replaced with a notice explaining the reason for removal.

Types of Papers

• Hypothesis-driven research and results containing important information relevant to the aims and scope of the Journal. The text should be arranged in the order: Abstract, Introduction, Materials and Methods, Results, Discussion, Conclusions, Acknowledgements.

• Experience reports designed to provide a vehicle for a group to describe their experience with a new technology or method or a novel approach to using an existing technology. The text should be arranged in the order: Abstract, Background, Methods, Results, Discussion, Conclusion, and Acknowledgements.

• Technical notes or technical tutorials with descriptions of how authors accomplished a particular task in a novel way. The text should be arranged in the order: Abstract, Background, Methods, Results, Discussion, Conclusion, and Acknowledgements.

• Reviews or tutorial based on extensive review of the literature. The text should be arranged in the order: Abstract, Background or Introduction, Review, Discussion, Summary, Acknowledgements.

All four types of manuscripts will undergo the same rigorous review process. Experience reports and Technical notes should contain an abstract, a description of the background of the project, detailed methods and results, and a discussion of the ways their methods are superior to previous methods. If software is to be included to be provided for reader’s use, this software must be included in the submission along with a user’s manual for installation and use. Reviews should include an introduction, a detailed review of the literature, a discussion and summary.

If you use the Cancer Imaging Archive (TCIA) for your research, JDI requires that you include a link in your publication to the imaging data used in your analysis. TCIA, a National Cancer Institute-funded online archive can provide a digital object identifier (DOI) that will link directly to publicly-accessible cancer imaging data that is downloadable from its website.

Citing the specific data used in your manuscript will help address growing concerns among the community relating to the transparency and reproducibility of biomedical research. TCIA’s DOI system makes citing data easy to do and provides a special web page for your DOI where researchers can directly download all of the data referenced in your publication.

The Cancer Imaging Archive is operated by Washington University School of Medicine to facilitate data sharing by hosting cancer image collections, related analysis results and clinical information. TCIA staff assures all data is fully HIPAA compliant and well curated. As a service to the research community, TCIA has the ability to create persistent identifiers linked to subsets of data held within TCIA that authors may use as data citations in their publications. Researchers can publish collections using a digital object identifier (DOI) that TCIA links both to an identifying web page and an access method that delivers the data.

• TCIA DOIs are references to data within the TCIA repository, and are not references to specific publications.

• A DOI request related to data that is not managed by TCIA will not be granted.

• All information related to a TCIA DOI must be persistently managed by TCIA.

• Only publicly available data may be referenced by a DOI.

• Proposals for hosting datasets on TCIA will be reviewed by NCI for appropriateness and level of significance to cancer research.

For questions or help with creating a DOI for your next manuscript please see: https://wiki.cancerimagingarchive.net/display/DOI/TCIA+Analysis+Results

TCIA Digital Object Identifiers

Manuscript Submission

Manuscripts are submitted online to Journal of Digital Imaging via Editorial Manager at https://www.editorialmanager.com/jdim/default.aspx or please follow the hyperlink "Submit Online" on the right and upload all of your manuscript files following the instructions given on the screen.

IF YOU ARE UNABLE TO SUBMIT YOUR MANUSCRIPT VIA EDITORIAL MANAGER OR HAVE ANY QUESTIONS CONCERNING THE SUBMISSION PROCESS, PLEASE CONTACT THE EDITORIAL OFFICE:

The Society for Imaging Informatics in Medicine

19440 Golf Vista Plaza, Suite 330

Leesburg, Virginia 20176

Telephone: (703) 723-0432

Fax: (703) 723-0415

E-mail: JDI@siim.org

Submission of a manuscript implies: that the work described has not been published before; that it is not under consideration for publication anywhere else; that its publication has been approved by all co-authors, if any, as well as by the responsible authorities – tacitly or explicitly – at the institute where the work has been carried out. The publisher will not be held legally responsible should there be any claims for compensation. Permissions Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.

Manuscripts must be in English, and authors are urged to aim for clarity, brevity, and accuracy of information and language. Authors whose native language is not English should have their manuscripts checked for linguistic accuracy by a native English speaker.

EDITORIAL MANAGER

Preprint Server policy

SpringerNature journals encourage posting of preprints of primary research manuscripts on preprint servers such as arXiv, authors’ or institutional websites, and open communications between researchers whether on community preprint servers or preprint commenting platforms.

Preprints are defined as an author’s version of a research manuscript that are deposited on a public server prior to submission and peer review by a scientific journal. Posting of preprints is not considered prior publication and will not jeopardize consideration at Springer journals.

Authors should disclose details of preprint posting, including DOI and licensing terms, upon submission of the manuscript or at any other point during consideration at a SpringerNature journal. When the preprint is published in a journal, it becomes the author’s responsibility to ensure that the preprint record is updated with a publication reference, including the DOI and URL link to the published version of the article on the journal website.

Title Page

Please make sure your title page contains the following information.

Title

The title should be concise and informative.

Author information

  • The name(s) of the author(s)
  • The affiliation(s) of the author(s), i.e. institution, (department), city, (state), country
  • A clear indication and an active e-mail address of the corresponding author
  • If available, the 16-digit ORCID of the author(s)

If address information is provided with the affiliation(s) it will also be published.

For authors that are (temporarily) unaffiliated we will only capture their city and country of residence, not their e-mail address unless specifically requested.

Large Language Models (LLMs), such as ChatGPT, do not currently satisfy our authorship criteria. Notably an attribution of authorship carries with it accountability for the work, which cannot be effectively applied to LLMs. Use of an LLM should be properly documented in the Methods section (and if a Methods section is not available, in a suitable alternative part) of the manuscript.

Abstract

Please provide an abstract of 150 to 250 words. The abstract should not contain any undefined abbreviations or unspecified references.

For life science journals only (when applicable)

  • Trial registration number and date of registration for prospectively registered trials
  • Trial registration number and date of registration, followed by “retrospectively registered”, for retrospectively registered trials

Keywords

Please provide 4 to 6 keywords which can be used for indexing purposes.

Statements and Declarations

Relevant declarations, such as Competing Interests and Author Contributions, should be provided here. Please refer to the Statements and Declarations section, below, for details of declarations required for submission to this journal.

Manuscript Preparation

DOUBLE BLIND PEER REVIEW

This journal follows a double-blind reviewing procedure. Authors are therefore requested to submit two version of their manuscript:

• The full version including all author names and affiliations.

• A blinded manuscript without any author names and affiliations in the text or on the title page. Self-identifying citations and references in the article text should either be avoided or left blank.

TEXT FORMATTING

Manuscripts should be submitted in Word.

• Use a normal, plain font (e.g., 10-point Times Roman) for text.

• Use italics for emphasis.

• Use the automatic page numbering function to number the pages.

• Do not use multiple columns.

• Do not use field functions.

• Use tab stops or other commands for indents, not the space bar.

• Use the table function, not spreadsheets, to make tables.

• Use the equation editor or MathType for equations.

• Save your file in docx format (Word 2007 or higher) or doc format (older Word versions). [Please note: the Word-Template has been deleted]

LaTeX AND ONLINE SUBMISSION

Manuscripts with mathematical content can also be submitted in LaTeX.

All source files you upload in the online submission system will be automatically compiled into a single PDF file to be approved by you at the end of the submission process. While the compiled PDF will be used for peer review purposes, your uploaded source files will be transferred to the publisher for publication upon acceptance. Please do not use subfolders for your LaTeX submission, e.g. for figures or bibliographic files. Further technical information on uploading and compiling your LaTeX submission can be found under http://www.editorialmanager.de/pdf/latex/

ABSTRACT

Please provide an abstract of 150 to 250 words. The abstract should not contain any undefined abbreviations or unspecified references.

KEYWORDS

Please provide 4 to 6 keywords which can be used for indexing purposes.

HEADINGS

Please use no more than three levels of displayed headings.

ABBREVIATIONS

Abbreviations should be defined at first mention and used consistently thereafter.

FOOTNOTES

Footnotes can be used to give additional information, which may include the citation of a reference included in the reference list. They should not consist solely of a reference citation, and they should never include the bibliographic details of a reference. They should also not contain any figures or tables. Footnotes to the text are numbered consecutively; those to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data). Footnotes to the title or the authors of the article are not given reference symbols. Always use footnotes instead of endnotes.

ACKNOWLEDGMENTS

Acknowledgments of people, grants, funds, etc. should be placed in a separate section on the title page. The names of funding organizations should be written in full.

REFERENCES

The author is responsible for the accuracy of the references. References should be numbered consecutively in the order in which they are first cited. References given in tables or figure legends must be numbered in sequence with those in the text. References should be listed in numerical order in the reference section of the manuscript. Only works referred to in the text and already accepted for publication can be included:

• Articles from journals: Names(s) and initials of all author(s): full article title. Journal name as abbreviated in Index Medicus, Volume number: first and last page numbers, year of publication.

Zaidel M, Hopper K, Iyriboz T: Interactive web-based radiology teaching file. J Digit Imaging 12:203-204, 1999

• Articles from electronic publications: Names(s) and initials of all author(s): full article title. Journal name as abbreviated in Index Medicus, DOI number, and publication date.

Lee SW, Gleason NR: Port site tumor recurrence rates in a murine model of laparoscopic splenectomy decreased with increased experience. Surg Endosc, DOI: 10.1007/s102780000231, August 9, 2000

• Books: Name(s) and initials of all author(s): full book title, edition, place of publication: publisher, year of publication

Keppel, G: Design and Analysis: A Researcher’s Handbook, Englewood Cliffs, NJ: Prentice-Hall, 1991

• Web-based sources: Name of Company or Website. URL or hyperlink of website. Date when the material was accessed.

Roxio Inc. Napster. Available at http://www.napster.com. Accessed 26 January 2003.

Statements & Declarations

The following statements must be included on the separate Title Page under the heading 'Statements and Declarations'. Please note that submissions that do not include required statements will be returned as incomplete.

Funding

Please describe any sources of funding that have supported the work. The statement should include details of any grants received (please give the name of the funding agency and grant number).

Example statements:

“This work was supported by […] (Grant numbers […] and […]). Author A.B. has received research support from Company A.”

“The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.”

Competing Interests

Authors are required to disclose financial or non-financial interests that are directly or indirectly related to the work submitted for publication. Interests within the last 3 years of beginning the work (conducting the research and preparing the work for submission) should be reported. Interests outside the 3-year time frame must be disclosed if they could reasonably be perceived as influencing the submitted work.

Example statements:

“Financial interests: Author A and B declare they have no financial interests. Author C has received speaker and consultant honoraria from Company M. Dr. C has received speaker honorarium and research funding from Company M and Company N. Author D has received travel support from Company O. Non-financial interests: Author D has served on advisory boards for Company M and Company N.”

“The authors have no relevant financial or non-financial interests to disclose.”

Please refer to the “Competing Interests” section below for more information on how to complete these sections.

Author Contributions

Authors are encouraged to include a statement that specifies the contribution of every author to the research and preparation of the manuscript.

Example statement:

“All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by [full name], [full name] and [full name]. The first draft of the manuscript was written by [full name] and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.”

Please refer to the “Authorship Principles ” section below for more information on how to complete this section.

In addition to the above, manuscripts that report the results of studies involving humans and/or animals should include the following declarations:

Ethics approval

Authors of research involving human or animal subjects should include a statement that confirms that the study was approved (or granted exemption) by the appropriate institutional and/or national research ethics committee (including the name of the ethics committee and reference number, if available). For research involving animals, their data or biological material, authors should supply detailed information on the ethical treatment of their animals in their submission. If a study was granted exemption or did not require ethics approval, this should also be detailed in the manuscript.

“This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University B (Date.../No....).”

“This is an observational study. The XYZ Research Ethics Committee has confirmed that no ethical approval is required.”

For detailed information on relevant ethical standards and criteria, please refer to the sections on “Research involving human participants, their data or biological material”, “Research involving animals, their data or biological material”.

Consent to participate

For all research involving human subjects, freely-given, informed consent to participate in the study must be obtained from participants (or their parent or legal guardian in the case of children under 16) and a statement to this effect should appear in the manuscript.

Example statement:

“Informed consent was obtained from all individual participants included in the study.”

“Written informed consent was obtained from the parents.”

Please refer to the section on “Informed Consent” for additional help with completing this information.

Consent to publish

Individuals may consent to participate in a study, but object to having their data published in a journal article. If your manuscript contains any individual person’s data in any form (including any individual details, images or videos), consent for publication must be obtained from that person, or in the case of children, their parent or legal guardian. This is in particular applicable to case studies. A statement confirming that consent to publish has been received from all participants should appear in the manuscript.

Example statement:

“The authors affirm that human research participants provided informed consent for publication of the images in Figure(s) 1a, 1b and 1c.”

Please refer to the section on “Informed Consent” for additional help with completing this information.

Tables

  • All tables are to be numbered using Arabic numerals.
  • Tables should always be cited in text in consecutive numerical order.
  • For each table, please supply a table caption (title) explaining the components of the table.
  • Identify any previously published material by giving the original source in the form of a reference at the end of the table caption.
  • Footnotes to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data) and included beneath the table body.

Figures and Artwork

ELECTRONIC FIGURE SUBMISSION

• Supply all figures electronically.

• Indicate what graphics program was used to create the artwork.

• For vector graphics, the preferred format is EPS; for halftones, please use TIFF format. MS Office files are also acceptable.

• Vector graphics containing fonts must have the fonts embedded in the files.

• Name your figure files with Fig and the figure number, e.g., Fig1.eps.

LINE ART

• Definition: Black and white graphic with no shading.

• Do not use faint lines and/or lettering and check that all lines and lettering within the figures are legible at final size.

• All lines should be at least 0.1 mm (0.3 pt) wide.

• Scanned line drawings and line drawings in bitmap format should have a minimum resolution of 1200 dpi.

• Vector graphics containing fonts must have the fonts embedded in the files.

HALFTONE ART

• Definition: Photographs, drawings, or paintings with fine shading, etc.

• If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves.

• Halftones should have a minimum resolution of 300 dpi.

COMBINATION ART

• Definition: a combination of halftone and line art, e.g., halftones containing line drawing, extensive lettering, color diagrams, etc.

• Combination artwork should have a minimum resolution of 600 dpi.

COLOR ART

• Color art is free of charge for online publication.

• If black and white will be shown in the print version, make sure that the main information will still be visible. Many colors are not distinguishable from one another when converted to black and white. A simple way to check this is to make a xerographic copy to see if the necessary distinctions between the different colors are still apparent.

• If the figures will be printed in black and white, do not refer to color in the captions.

• Color illustrations should be submitted as RGB (8 bits per channel).

FIGURE LETTERING

• To add lettering, it is best to use Helvetica or Arial (sans serif fonts).

• Keep lettering consistently sized throughout your final-sized artwork, usually about 2–3 mm (8–12 pt).

• Variance of type size within an illustration should be minimal, e.g., do not 8-pt type on an axis and 20-pt type for the axis label.

• Avoid effects such as shading, outline letters, etc.

• Do not include titles or captions into your illustrations.

FIGURE NUMBERING

• All figures are to be numbered using Arabic numerals.

• Figures should always be cited in the text in consecutive numerical order.

• Figure parts should be denoted by lowercase letters (a, b, c, etc.).

• If an appendix appears in your article/chapter and it contains one or more figures, continue the consecutive numbering of the main text. Do not number the appendix figures, “A1, A2, A3, etc.” Figures in online appendices (Electronic supplementary Material) should, however, be numbered separately.

FIGURE CAPTIONS

• Each figure should have a concise caption describing accurately what the figure depicts. Include the captions in the text file of the manuscript, not in the figure file.

• Figure captions begin with the term Fig. in bold type, followed by the figure number, also in bold type.

• No punctuation is to be included after the number, nor is any punctuation to be placed at the end of the caption.

• Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs.

• Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.

FIGURE PLACEMENT AND SIZE

• Figures should be submitted separately from the text, if possible.

• When preparing your figures, size figures to fit in the column width.

• For most journals the figures should be 39 mm, 84 mm, 129 mm, or 174 mm wide and not higher than 234 mm.

• For books and book-sized journals, the figures should be 80 mm or 122 mm wide and not higher than 198 mm.

PERMISSIONS

If you include figures that have already been published elsewhere, you must obtain permission from the copyright owner(s) for both the print and online format. Please be aware that some publishers do not grant electronic rights for free and that Springer will not be able to refund any costs that may have occurred to receive these permissions. In such cases, material from other sources should be used.

ACCESSIBILITY

In order to give people of all abilities and disabilities access to the content of your figures, please make sure that

• All figures have descriptive captions (blind users could then use a text-tospeech software or a text-to-Braille hardware)

• Patterns are used instead or in addition to colors for conveying information (color-blind users would then be able to distinguish the visual elements)

• Any figure lettering has a contrast ratio of at least 4.5:1.

Supplementary Information (SI)

Springer accepts electronic multimedia files (animations, movies, audio, etc.) and other supplementary files to be published online along with an article or a book chapter. This feature can add dimension to the author's article, as certain information cannot be printed or is more convenient in electronic form.

Before submitting research datasets as Supplementary Information, authors should read the journal’s Research data policy. We encourage research data to be archived in data repositories wherever possible.

Submission

  • Supply all supplementary material in standard file formats.
  • Please include in each file the following information: article title, journal name, author names; affiliation and e-mail address of the corresponding author.
  • To accommodate user downloads, please keep in mind that larger-sized files may require very long download times and that some users may experience other problems during downloading.
  • High resolution (streamable quality) videos can be submitted up to a maximum of 25GB; low resolution videos should not be larger than 5GB.

Audio, Video, and Animations

  • Aspect ratio: 16:9 or 4:3
  • Maximum file size: 25 GB for high resolution files; 5 GB for low resolution files
  • Minimum video duration: 1 sec
  • Supported file formats: avi, wmv, mp4, mov, m2p, mp2, mpg, mpeg, flv, mxf, mts, m4v, 3gp

Text and Presentations

  • Submit your material in PDF format; .doc or .ppt files are not suitable for long-term viability.
  • A collection of figures may also be combined in a PDF file.

Spreadsheets

  • Spreadsheets should be submitted as .csv or .xlsx files (MS Excel).

Specialized Formats

  • Specialized format such as .pdb (chemical), .wrl (VRML), .nb (Mathematica notebook), and .tex can also be supplied.

Collecting Multiple Files

  • It is possible to collect multiple files in a .zip or .gz file.

Numbering

  • If supplying any supplementary material, the text must make specific mention of the material as a citation, similar to that of figures and tables.
  • Refer to the supplementary files as “Online Resource”, e.g., "... as shown in the animation (Online Resource 3)", “... additional data are given in Online Resource 4”.
  • Name the files consecutively, e.g. “ESM_3.mpg”, “ESM_4.pdf”.

Captions

  • For each supplementary material, please supply a concise caption describing the content of the file.

Processing of supplementary files

  • Supplementary Information (SI) will be published as received from the author without any conversion, editing, or reformatting.

Accessibility

In order to give people of all abilities and disabilities access to the content of your supplementary files, please make sure that

  • The manuscript contains a descriptive caption for each supplementary material
  • Video files do not contain anything that flashes more than three times per second (so that users prone to seizures caused by such effects are not put at risk)

Generative AI Images

Please check Springer’s policy on generative AI images and make sure your work adheres to the principles described therein.

After acceptance

Upon acceptance, your article will be exported to Production to undergo typesetting. Shortly after this you will receive two e-mails. One contains a request to confirm your affiliation, choose the publishing model for your article, as well as to arrange rights and payment of any associated publication cost. A second e-mail containing a link to your article’s proofs will be sent once typesetting is completed.

Article publishing agreement

Depending on the ownership of the journal and its policies, you will either grant the Publisher an exclusive licence to publish the article or will be asked to transfer copyright of the article to the Publisher.

Offprints

Offprints can be ordered by the corresponding author.

Color illustrations

Online publication of color illustrations is free of charge. For color in the print version, authors will be expected to make a contribution towards the extra costs.

Proof reading

The purpose of the proof is to check for typesetting or conversion errors and the completeness and accuracy of the text, tables and figures. Substantial changes in content, e.g., new results, corrected values, title and authorship, are not allowed without the approval of the Editor.

After online publication, further changes can only be made in the form of an Erratum, which will be hyperlinked to the article.

Online First

The article will be published online after receipt of the corrected proofs. This is the official first publication citable with the DOI. After release of the printed version, the paper can also be cited by issue and page numbers.

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