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  • Reference work
  • © 2017

Biomarkers in Bone Disease

  • Embraces a holistic approach to many conditions that affect the skeletal system
  • Describes biomarkers in terms of conventional, new and emerging analytes, techniques, platforms and applications
  • Updates scientists and professionals on advances across the disciplines
  • Identifies key facts and defines words and terms for the lay person
  • Opens the field to the all readers inquiring into this imperative area of research
  • Includes supplementary material: sn.pub/extras

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Table of contents (51 entries)

  1. Front Matter

    Pages i-xxvii
  2. General Aspects and Introductory Material

    1. Front Matter

      Pages 1-1
    2. Overview of Biochemical Markers of Bone Metabolism

      • Pamela Maffioli, Giuseppe Derosa
      Pages 3-21
    3. Osteosarcoma Biomarkers Discovery Using “Omics” Approaches

      • Giulia Bernardini, Maurizio Orlandini, Federico Galvagni, Annalisa Santucci
      Pages 23-46
    4. Bone Markers Throughout Sexual Development: Epidemiological Significance and Population-Based Findings

      • Raquel Lucas, Ana Martins, Teresa Monjardino, Joana Caetano-Lopes, João Eurico Fonseca
      Pages 71-104
  3. Body Fluids, Tissue, and Specific Biomarkers

    1. Front Matter

      Pages 155-155
    2. Sirtuins as Markers of Bone Disease: A Focus on Osteoarthritis and Osteoporosis

      • Élie Abed, Pascal Reboul, Daniel Lajeunesse
      Pages 157-175
    3. Creatine Kinase as Biomarker in Osteogenesis Imperfecta

      • Patrizia D’Eufemia, Mauro Celli, Anna Zambrano, Roberto Finocchiaro
      Pages 177-199
    4. Circulating Sclerostin in Bone Sclerosing Disorders

      • Antoon H. van Lierop, Socrates E. Papapoulos
      Pages 221-237
    5. Pentraxin 3 (PTX3) as a Biomarker of Bone Disease

      • Bongkun Choi, Eun-Ju Chang
      Pages 253-265
    6. Ameloblastin as Biomarker of Bone

      • Juliane Isaac, Guilhem Lignon, Jaime Jacques, Ariane Berdal
      Pages 267-300
    7. Chitinases as Biomarkers in Bone Studies

      • Michelino Di Rosa, Lucia Malaguarnera
      Pages 301-327
    8. Hormone Relaxin as Biomarker for Bone Health and Disease

      • Yukiho Kobayashi, Carolina Duarte, Keiji Moriyama
      Pages 329-353
    9. Pentosidine as a Biomarker for Poor Bone Quality and Elevated Fracture Risk

      • Janet M. Pritchard, Thomas L. Willett
      Pages 355-392

About this book

There are many conditions that affect the skeletal system. On a worldwide basis, osteoarthritis alone affects 10%-15 percent of those over 60 years of age and in some countries more than 30-50% of postmenopausal women will have osteopenia or osteoporosis. With the increasing ageing population, maintaining skeletal health is particularly important. Fractures in the aged, for example, can lead to premature deaths. It is therefore imperative that appropriate use is made of conventional, new and emerging biomarker platforms.  Biomarkers in Bone Disease  embraces a holistic approach by combining information on different conditions that affect the skeletal system and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge, trends and innovations. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.

Editors and Affiliations

  • Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster, London, United Kingdom

    Vinood B. Patel

  • Department of Nutrition and Dietetics, Division of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom

    Victor R. Preedy

About the editors

Professor Victor R. Preedy is a senior faculty member of King's College London (Professor of Nutritional Biochemistry) and King's College Hospital (Professor of Clinical Biochemistry). He is attached to both the Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics. He is also Director of the Genomics Centre and a member of the School of Medicine. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1993 he gained his second doctoral degree, for his outstanding contribution to protein metabolism in health and disease. He has received membership and fellowship of a number of academic and professional bodies in the UK, including the Royal College of Pathologists, the Royal Institute of Public Health, and the Royal Society of Chemistry. Professor Preedy has published over 570 articles, which includes 165 peer-reviewed manuscripts based on original research, 100 reviews, and over 50 books and book volumes.

Bibliographic Information

Buy it now

Buying options

eBook USD 379.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access