Methods in Molecular Biology

Data Production and Analysis in Population Genomics

Methods and Protocols

Editors: Pompanon, Francois, Bonin, Aurelie (Eds.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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  • ISBN 978-1-61779-870-2
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Hardcover 119,99 €
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About this book

Population genomics is a recently emerged discipline, which aims at understanding how evolutionary processes influence genetic variation across genomes. Today, in the era of cheaper next-generation sequencing, it is no longer as daunting to obtain whole genome data for any species of interest and population genomics is now conceivable in a wide range of fields, from medicine and pharmacology to ecology and evolutionary biology. However, because of the lack of reference genome and of enough a priori data on the polymorphism, population genomics analyses of populations will still involve higher constraints for researchers working on non-model organisms, as regards the choice of the genotyping/sequencing technique or that of the analysis methods. Therefore, Data Production and Analysis in Population Genomics purposely puts emphasis on protocols and methods that are applicable to species where genomic resources are still scarce. It is divided into three convenient sections, each one tackling one of the main challenges facing scientists setting up a population genomics study. The first section helps devising a sampling and/or experimental design suitable to address the biological question of interest. The second section addresses how to implement the best genotyping or sequencing method to obtain the required data given the time and cost constraints as well as the other genetic resources already available, Finally, the last section is about making the most of the (generally huge) dataset produced by using appropriate analysis methods in order to reach a biologically relevant conclusion. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, advice on methodology and implementation, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and easily accessible, Data Production and Analysis in Population Genomics serves a wide readership by providing guidelines to help choose and implement the best experimental or analytical strategy for a given purpose.

Table of contents (18 chapters)

  • Sampling in Landscape Genomics

    Manel, Stéphanie (et al.)

    Pages 3-12

    Preview Buy Chapter 39,95 €
  • OligoTag: A Program for Designing Sets of Tags for Next-Generation Sequencing of Multiplexed Samples

    Coissac, Eric

    Pages 13-31

    Preview Buy Chapter 39,95 €
  • SNP Discovery in Non-model Organisms Using 454 Next Generation Sequencing

    Wheat, Christopher W.

    Pages 33-53

    Preview Buy Chapter 39,95 €
  • In Silico Fingerprinting (ISIF): A User-Friendly In Silico AFLP Program

    Paris, Margot (et al.)

    Pages 55-64

    Preview Buy Chapter 39,95 €
  • Diversity Arrays Technology: A Generic Genome Profiling Technology on Open Platforms

    Kilian, Andrzej (et al.)

    Pages 67-89

    Preview Buy Chapter 39,95 €

Buy this book

eBook 101,14 €
price for India (gross)
  • ISBN 978-1-61779-870-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 119,99 €
price for India (gross)
  • ISBN 978-1-61779-869-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Data Production and Analysis in Population Genomics
Book Subtitle
Methods and Protocols
Editors
  • Francois Pompanon
  • Aurelie Bonin
Series Title
Methods in Molecular Biology
Series Volume
888
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-61779-870-2
DOI
10.1007/978-1-61779-870-2
Hardcover ISBN
978-1-61779-869-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 337
Topics