Editors:
- Comprehensive lab manual for mitochondrial research
- Introduction to different model organisms for studying mitochondrial function
- Fusion and fission of mitochondria
- Biogenesis of mitochondria
- Detailed overview of functional genomic approaches for studying mitochondrial function
Part of the book series: Methods in Molecular Biology (MIMB, volume 372)
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Table of contents (39 protocols)
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Front Matter
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Model Systems to Study Mitochondrial Functions
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Front Matter
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Genetics and Molecular Biology
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Front Matter
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Biochemistry
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Front Matter
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About this book
Mitochondria: Practical Protocols offers a broad collection of methods for studying the molecular biology, function, and features of mitochondria. In the past decade, mitochondrial research has elucidated the important influence of mitochondrial processes on integral cell processes such as apoptosis and cellular aging. This practical guide presents a wide spectrum of mitochondrial methods, each written by specialists with solid experience and intended for implementation by novice and expert researchers alike.
Part I introduces major experimental model systems and discusses their specific advantages and limitations for functional analysis of mitochondria. The concise overview of general properties of mitochondrial systems is supplemented by detailed protocols for cultivation of model organisms. Parts II-VI comprise a robust collection of protocols for studying different molecular aspects of mitochondrial functions including: genetics and microbiology, biochemistry, physiology, dynamics and morphology, and functional genomics. Emphasis is placed on new and emerging topics in mitochondrial study, such as the examination of apoptotic effects, fusion and fission of mitochondria, and proteome and transcriptome analysis.
Editors and Affiliations
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Department für Biologie I, Botanik, Ludwig-Maximilians-Universität München, München, Germany
Dario Leister
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Zellbiologie, Universität Kaiserslautern, Kaiserslautern, Germany
Johannes M. Herrmann
Bibliographic Information
Book Title: Mitochondria
Book Subtitle: Practical Protocols
Editors: Dario Leister, Johannes M. Herrmann
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-365-3
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2007
Hardcover ISBN: 978-1-58829-667-2Published: 12 June 2007
Softcover ISBN: 978-1-62703-833-1Published: 26 November 2014
eBook ISBN: 978-1-59745-365-3Published: 05 February 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVI, 586
Topics: Cell Biology, Human Genetics