Coronary Vasomotion Abnormalities

1. Front Matter

   Pages i-vii

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2. Epicardial Coronary Artery Spasm

   1. Front Matter

      Pages 1-1

      PDF

   2. Epidemiology of Vasospastic Angina

      • Jun Takahashi, Hiroaki Shimokawa

      Pages 3-19

   3. Pathophysiology and Molecular Mechanisms of Coronary Artery Spasm

      • Kimio Satoh, Hiroaki Shimokawa

      Pages 21-37

   4. Diagnosis of Coronary Artery Spasm

      • Kensuke Nishimiya, Yasuharu Matsumoto, Jun Takahashi, Hiroaki Shimokawa

      Pages 39-57

   5. Treatment of Coronary Artery Spasm

      • Yasuharu Matsumoto, Kensuke Nishimiya, Kazuma Ohyama, Hironori Uzuka, Hirokazu Amamizu, Jun Takahashi et al.

      Pages 59-76

3. Coronary Microvascular Dysfunction

   1. Front Matter

      Pages 77-77

      PDF

   2. Epidemiology of Coronary Microvascular Dysfunction

      • Peter Ong, Hiroaki Shimokawa

      Pages 79-95

   3. Pathophysiology of Coronary Microvascular Dysfunction

      • Shigeo Godo, Hiroaki Shimokawa

      Pages 97-118

   4. Diagnosis of Coronary Microvascular Dysfunction

      • Jun Takahashi, Hiroaki Shimokawa

      Pages 119-137

   5. Treatment of Coronary Microvascular Dysfunction

      • Jun Takahashi, Hiroaki Shimokawa

      Pages 139-155

This book reviews the latest findings on epicardial coronary spasm and coronary microvascular dysfunction (CMD), important diseases for understanding coronary artery vasomotion abnormalities. The book chiefly consists of two major parts, each of which explores the epidemiology, pathophysiology, diagnosis and treatment of the diseases. The chapters present a range of experimental and clinical studies, including the editor’s life’s work on coronary spasm; how Rho-kinase activation plays an important role in connection with the disease; how chronic adventitial inflammation is a central pathophysiology of the spasm; the importance of Rho-kinase activation in the pathogenesis of CMD; how epicardial spasm and CMD frequently co-exist; and much more. Coronary Vasomotion Abnormalities will help practicing cardiologists, cardiac surgeons, vascular biologists and radiologists understand the latest issues concerning the clinical, interventional, and surgical management of these conditions, and offer these readers valuable insights into the effective treatment of microvascular angina. 

• Coronary Microvascular Dysfunction
• Coronary Artery Spasm
• Vasospastic Angina
• Coronary Artery Vasomotion
• Coronary Intervention Surgery
• Coronary Bypass Surgery
• Microvascular Angina
• Rho-kinase inhibitor
• Fasudil
• CMD
• VSA
• MVA
• Epicardial Spasm

• Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

  Hiroaki Shimokawa

Hiroaki Shimokawa, MD, PhD

Professor and Chairman

Department of Cardiovascular Medicine

Tohoku University Graduate School of Medicine

Sendai 980-8574, Japan.

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