Overview
- Emphasis is given on clinical studies
- Preclinical experiences have been shared
- Adequate number of illustrations are provided in the book for easier and better understanding of the content in each chapter
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Table of contents (29 chapters)
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Front Matter
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Disease Biology and Basic Stem Cells
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Front Matter
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Potential Clinical Studies
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Front Matter
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Keywords
About this book
This book discusses the two different cellular approaches that are pursued in regenerative medicine: cell therapy and tissue engineering. It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells. The interest in MSCs can be seen in more than 150 clinical trials, some of which have progressed to Phase III, despite the cells’ limited differentiation potential. The book also explores how embryonic stem (ES) cells, being pluripotent in nature, can resolve some of the problems associated with adult stem cells, yet entail other challenges like risks of teratoma formation and immune rejection. A separate chapter deals with the role of noncoding RNAs in neuronal commitment of induced pluripotent stem (iPS) cells.
Chapters like “Cord blood banking in India and the global scenario”; “3D bioprinting of tissue” and others will make this book an extremely interesting read for all students, researchers and clinicians working in the area of regenerative medicine/stem cells.
The book is broadly divided into two parts, the first of which is devoted to basic information on stem cells, and the second of which addresses potential clinical applications in the areas of hematology, cardiology, orthopedic and immune suppression, etc.
Editors and Affiliations
About the editor
Dr. Asok Mukhopadhyay has just retired from the very prestigious National Institute of Immunology, New Delhi after more than 25 years of service as a Scientist & Principle Investigator. He received his PhD from the Indian Institute of Technology, New Delhi and worked as a Post-Doctoral Research Fellow at MD Anderson Cancer Center, Houston, Texas, USA. His main area of research is stem cells in regenerative medicine. He has published 75 research papers, contributed to 7 book chapters and has also written the textbook “Animal Cell Technology” [Published by IK International, New Delhi; ISBN: 978-81-89866-96-9 (2009)]. Further, he holds 2 Indian patents.
Dr. Mukhopadhyay is a member of the Scientific Advisory Committee of several leading Indian institutions, as well as the Task Force on ‘Stem Cells Research and Regenerative Medicine’- Department of Biotechnology, Government of India. He also serves as a reviewer for various reputed journals such as Tissue Engineering, World Journal of Stem Cell Research, Biotechnology & Bioengineering, and Stem cells and Development.Bibliographic Information
Book Title: Regenerative Medicine: Laboratory to Clinic
Editors: Asok Mukhopadhyay
DOI: https://doi.org/10.1007/978-981-10-3701-6
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2017
Hardcover ISBN: 978-981-10-3700-9Published: 09 October 2017
Softcover ISBN: 978-981-10-9945-8Published: 22 August 2018
eBook ISBN: 978-981-10-3701-6Published: 21 September 2017
Edition Number: 1
Number of Pages: XIX, 537
Number of Illustrations: 6 b/w illustrations, 75 illustrations in colour
Topics: Regenerative Medicine/Tissue Engineering, Laboratory Medicine, Stem Cells, Biomedical Engineering/Biotechnology, Human Physiology