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  • Book
  • © 2016

Application of Clinical Bioinformatics

  • Introduces the application of genetic, biological and medical information
  • Provides practical examples
  • Written by experts in this field
  • Includes supplementary material: sn.pub/extras

Part of the book series: Translational Bioinformatics (TRBIO, volume 11)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-vi
  2. Biostatistics, Data Mining and Computational Modeling

    • Hao He, Dongdong Lin, Jigang Zhang, Yuping Wang, Hong-Wen Deng
    Pages 23-57
  3. Gene Expression and Profiling

    • Yu Zhou, Chao Xu, Jigang Zhang, Hong-Wen Deng
    Pages 59-82
  4. The Next Generation Sequencing and Applications in Clinical Research

    • Junbo Duan, Xiaoying Fu, Jigang Zhang, Yu-Ping Wang, Hong-Wen Deng
    Pages 83-113
  5. Clinical Epigenetics and Epigenomics

    • Nian Dong, Lin Shi, Chengshui Chen, Wenhuan Ma, Xiangdong Wang
    Pages 115-132
  6. Proteomic Profiling: Data Mining and Analyses

    • Lan Zhang, Wei Zhu, Yong Zeng, Jigang Zhang, Hong-Wen Deng
    Pages 133-173
  7. Targeted Metabolomics: The Next Generation of Clinical Chemistry!

    • Klaus M. Weinberger, Marc Breit
    Pages 175-211
  8. Clinical Bioinformatics for Biomarker Discovery in Targeted Metabolomics

    • Marc Breit, Christian Baumgartner, Michael Netzer, Klaus M. Weinberger
    Pages 213-240
  9. Metagenomic Profiling, Interaction of Genomics with Meta-genomics

    • Ruifeng Wang, Yu Zhou, Shaolong Cao, Yuping Wang, Jigang Zhang, Hong-Wen Deng
    Pages 241-267
  10. Clinical Epigenetics and Epigenomics

    • Chuan Qiu, Fangtang Yu, Hong-Wen Deng, Hui Shen
    Pages 269-293
  11. Integrative Biological Databases

    • Jinzeng Wang, Haiyun Wang
    Pages 295-307
  12. Standards and Regulations for (Bio)Medical Software

    • Jörg Schröttner, Robert Neubauer, Christian Baumgartner
    Pages 309-321
  13. Clinical Applications and Systems Biomedicine

    • Duojiao Wu, David E. Sanin, Xiangdong Wang
    Pages 323-335
  14. Heterogeneity of Hepatocellular Carcinoma

    • Tingting Fang, Li Feng, Jinglin Xia
    Pages 371-398

About this book


This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.


Editors and Affiliations

  • Shanghai Inst.of Clinical Bioinformatics, Zhongshan Hospital, Fudan University, Shang Hai, China

    Xiangdong Wang

  • Institute of Health Care Engineering, Graz University of Technology, Graz, Austria

    Christian Baumgartner

  • School Of Medicine & Medical Science, University College Dublin, Dublin 4, Ireland

    Denis C. Shields

  • Health and Tropical Medicine, Tulane University School of Public Healt, New Orleans, USA

    Hong-Wen Deng

  • Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland

    Jacques S Beckmann

Bibliographic Information

  • Book Title: Application of Clinical Bioinformatics

  • Editors: Xiangdong Wang, Christian Baumgartner, Denis C. Shields, Hong-Wen Deng, Jacques S Beckmann

  • Series Title: Translational Bioinformatics

  • DOI: https://doi.org/10.1007/978-94-017-7543-4

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2016

  • Hardcover ISBN: 978-94-017-7541-0Published: 13 April 2016

  • Softcover ISBN: 978-94-024-1375-5Published: 25 April 2018

  • eBook ISBN: 978-94-017-7543-4Published: 31 March 2016

  • Series ISSN: 2213-2775

  • Series E-ISSN: 2213-2783

  • Edition Number: 1

  • Number of Pages: VI, 398

  • Number of Illustrations: 50 b/w illustrations, 70 illustrations in colour

  • Topics: Biomedicine general, Bioinformatics, Health Informatics

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access