Overview
- Editors:
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Daniel A. Abramowicz
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Biological Sciences Laboratory, General Electric Company, Schenectady, USA
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Table of contents (17 chapters)
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Front Matter
Pages i-xxvii
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- Cary J. Morrow, J. Shield Wallace
Pages 25-62
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- Daniel A. Abramowicz, Charles R. Keese, Suzanne H. Lockwood
Pages 63-92
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- J. W. Frost, L. M. Reimer, K. M. Draths, D. L. Pompliano, D. L. Conley
Pages 93-113
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- Steven P. Crump, Jeffery S. Heier, J. David Rozzell
Pages 115-133
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- Robert A. Lazarus, Jana L. Seymour, R. Kevin Stafford, Mark S. Dennis, Margery G. Lazarus, Cara B. Marks et al.
Pages 135-155
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- F. X. McConville, J. L. Lopez, S. A. Wald
Pages 167-177
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- Roy M. Daniel, Judy Bragger, Hugh W. Morgan
Pages 243-254
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- J. Gregory Zeikus, Susan E. Lowe, Badal C. Saha
Pages 255-276
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- Toru Nagasawa, Hideaki Yamada
Pages 277-318
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Back Matter
Pages 365-369
About this book
The action of enzymes fascinated mankind long before they were rec ognized for the complex chemicals that they are. The first application of these remarkable compounds to produce ethanol by fermentation is lost to antiquity. Payer and Persoz (Ann. Chim. Phys. , 53, 73 (1833ii)) appear to have provided the first step toward understanding this com plex area when they reported the isolation of diastase in 1833. These workers showed that diastase could catalyze the hydrolysis of starches to sugars. Somewhat earlier Kirchhoff (Schwigger's Journal, 4, 108 (1812)) had shown that a small amount of dilute acid could hydrolyze a seemingly endless amount of starch to sugars. The genius of Berzelius recognized the commonality of these two observations in connection with a few other isolated observations and in 1834 coined the term catalysis to describe such actions. Professor Leibig was one of the giants of the chemical world in 1840. In addition to his own work, Liebig was training the world's next generation of chemists in his laboratory in Giessen. This cadre of chemists were very impressed by the master teacher so that is it only natural that Liebig's views should dominate with this next generation of chemists. Leibig was, in the 1830s and 1840s, developing his mastery of agricultural chemistry. The mechanism of putrefication was of great concern to Leibig, and he turned to the newly defined area of catalysis for an explanation.
Reviews
This useful and interesting book, with a subject index and chapter summaries. The concluding chapter by antonies Kieboom is a particularly thoughtful analysis of why carbohydrate-converting enzymes may be catalytically inactive in water-free solvents, unless the product is much less popular than the substrate. It is suggested here that a too tight enzyme-substrate or enzyme- product complex is formed in a apolar organic solvent. Chemistry and Industry; This useful and interesting book, with a subject index and chapter summaries. The concluding chapter by antonies Kieboom is a particularly thoughtful analysis of why carbohydrate-converting enzymes may be catalytically inactive in water-free solvents, unless the product is much less popular than the substrate. It is suggested here that a too tight enzyme-substrate or enzyme- product complex is formed in a apolar organic solvent. Chemistry and Industry
Editors and Affiliations
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Biological Sciences Laboratory, General Electric Company, Schenectady, USA
Daniel A. Abramowicz
