Overview
- First comprehensive book on stem cell aging and rejuvenation
- Depicts the mechanism of aging in different tissues
- Covers model organisms and mammalian systems
- Written by prominent experts in the field?
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Table of contents (16 chapters)
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Front Matter
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Introduction
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Front Matter
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Mechanisms of Stem Cell Aging: Lessons from Model Organisms
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Front Matter
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Mechanisms of Stem Cell Aging in Mammalian Tissues
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Front Matter
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Stem Cells, Diseases of Aging and Rejuvenation
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Front Matter
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Keywords
About this book
Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stemcells, aging mechanisms or age-related diseases.
Reviews
“This book discusses the impact of aging on the many stem cell populations, the pathologies associated with the decline of stem cell functions, and the use of stem cells to attenuate stem cell aging. … The purpose is to provide a reference for researchers working in the field of healthy aging. The audience is clinicians and all scientists working in the field of aging, stem cells, and regenerative medicine.” (Michele Fornaro, Doody's Book Reviews, October, 2015)
Editors and Affiliations
About the editors
Hartmut Geiger studied chemistry and biochemistry at the Universities of Karlsruhe and Witten/Herdecke in Germany. He received his PhD from the Max-Planck-Institute for Immunobiology in Freiburg, Germany in 1999. From 1999 to 2002 he was scientific research fellow at the University of Kentucky, USA with expertise in stem cells, genetics and aging. From 2002 to 2008 he was Assistant Professor at the Division of Experimental Hematology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, USA. Since 2008 he has been Associate Professor at the University of Cincinnati, USA and Professor at the University of Ulm, Division of Dermatology and Allergic Diseases, Germany. His main research interest lies in the molecular biology of aging.
Bibliographic Information
Book Title: Stem Cell Aging: Mechanisms, Consequences, Rejuvenation
Editors: Hartmut Geiger, Heinrich Jasper, Maria Carolina Florian
DOI: https://doi.org/10.1007/978-3-7091-1232-8
Publisher: Springer Vienna
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Wien 2015
Hardcover ISBN: 978-3-7091-1231-1Published: 15 July 2015
Softcover ISBN: 978-3-7091-1959-4Published: 18 October 2016
eBook ISBN: 978-3-7091-1232-8Published: 06 July 2015
Edition Number: 1
Number of Pages: XI, 354
Number of Illustrations: 1 b/w illustrations, 32 illustrations in colour
Topics: Stem Cells, Cancer Research, Immunology, Hematology