Skip to main content
  • Book
  • © 2018

Cellular Dedifferentiation and Regenerative Medicine

  • Systematically reviews cell dedifferentiation and regenerative medicine

  • Reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases

  • Offers detailed descriptions, from the cell dedifferentiation phenomenon to molecular mechanisms, to clinical applications in regenerative medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
  2. Central Nervous System and Dedifferentiation

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 1-17
  3. Peripheral Nerve Regeneration and Dedifferentiation

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 19-37
  4. Dedifferentiation and the Heart

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 39-64
  5. Dedifferentiation and Kidney System

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 65-90
  6. Dedifferentiation and Musculoskeletal Repair and Regeneration

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 91-116
  7. Dedifferentiation and Skin Regeneration

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 117-131
  8. Dedifferentiation and Vision System

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 133-162
  9. Blood Vessel Repair, Atherosclerosis, and Dedifferentiation

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 163-173
  10. Dedifferentiation and Adipose Tissue

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 175-193
  11. Dedifferentiation and Organ Regeneration

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 195-245
  12. Dedifferentiation and Regenerative Medicine: The Past and the Future

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 247-271
  13. Authors’ Related Publications

    • Xiaobing Fu, Andong Zhao, Tian Hu
    Pages 273-280
  14. Back Matter

    Pages 281-291

About this book

This book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications.

The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine.

The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence. 

Authors and Affiliations

  • Key Laboratory of Wound Repair and Regeneration of PLA, The First Hospital Affiliated to the PLA General Hospital, Beijing, China

    Xiaobing Fu

  • Tianjin Medical University, Tianjin, China

    Andong Zhao

  • School of Medicine, Nankai University, Tianjin, China

    Tian Hu

About the authors

Xiaobing Fu is a professor and director of the Key Laboratory of Wound Repair and Regenerative Medicine of PLA, The College of Life Sciences of the PLA General Hospital, Beijing, China. Professor Fu is also an academician of Chinese Academy of Engineering (Division of Medicine and Health). Andong Zhao is a doctor from Tianjin Medical University, Tianjin, China. Tian Hu is a doctor at the School of medicine, Nankai University, China.

Bibliographic Information

  • Book Title: Cellular Dedifferentiation and Regenerative Medicine

  • Authors: Xiaobing Fu, Andong Zhao, Tian Hu

  • DOI: https://doi.org/10.1007/978-3-662-56179-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag GmbH Germany 2018

  • Hardcover ISBN: 978-3-662-56177-5Published: 20 February 2018

  • Softcover ISBN: 978-3-662-57257-3Published: 04 June 2019

  • eBook ISBN: 978-3-662-56179-9Published: 09 February 2018

  • Edition Number: 1

  • Number of Pages: XII, 291

  • Number of Illustrations: 6 b/w illustrations, 21 illustrations in colour

  • Topics: Traumatic Surgery, Dermatology, Regenerative Medicine/Tissue Engineering

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access