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Organ-Selective Actions of Steroid Hormones

  • Conference proceedings
  • © 1995

Overview

Editors:
  1. D. T. Baird

    1. Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, Scotland

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  2. G. Schütz

    1. German Cancer Research Center, Molecular Biology of the Cell I, Heidelberg, Germany

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  3. R. Krattenmacher

    1. Research Laboratories of Schering AG, Berlin, Germany

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Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 16)

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Table of contents (9 papers)

  1. Front Matter

    Pages I-XIV
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  2. Development of Tissue-Selective Estrogen Receptor Modulators

    • D. P. McDonnell, B. A. Lieberman, J. Norris
    Pages 1-28

  3. Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Interactions with Second Messenger Signaling Pathways

    • B. S. Katzenellenbogen, M. M. Montano, W. L. Kraus, S. M. Aronica, N. Fujimoto, P. LeGoff
    Pages 29-50

  4. Analysis of Genetically Altered Mice Without Glucocorticoid Receptor

    • W. Schmid, T. Cole, J. Blendy, L. Montoliu, G. Schütz
    Pages 51-63

  5. Organ-Selective Actions of Tamoxifen and Other Partial Antiestrogens

    • R. T. Turner
    Pages 65-84

  6. Progestin Regulation of Cell Proliferation in the Breast and Endometrium

    • R. L. Sutherland, C. S. L. Lee, A. L. Cornish, E. A. Musgrove
    Pages 85-105

  7. Central Versus Endometrial Effects of Antiprogestins: Is Endometrial Selectivity Possible?

    • M. Bygdeman, K. Gemzell-Danielsson, M. L. Swahn
    Pages 107-120

  8. Androgen Action on the Bone

    • J. S. Finkelstein
    Pages 121-136

  9. General Principles of Vitamin D Action and Mechanism-Based Search for Analogs with Specific Actions

    • H. F. DeLuca, C. Zierold, H. M. Darwish
    Pages 137-159

  10. Organ-Specific Actions of Vitamin D Analogs: Relevance of Rapid Effects

    • M. C. Farach-Carson, S. E. Guggino
    Pages 161-180

  11. Back Matter

    Pages 181-184
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Keywords

About this book

Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, with the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity.

Editors and Affiliations

  • Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, Scotland

    D. T. Baird

  • German Cancer Research Center, Molecular Biology of the Cell I, Heidelberg, Germany

    G. Schütz

  • Research Laboratories of Schering AG, Berlin, Germany

    R. Krattenmacher

Bibliographic Information

  • Book Title: Organ-Selective Actions of Steroid Hormones

  • Editors: D. T. Baird, G. Schütz, R. Krattenmacher

  • Series Title: Ernst Schering Foundation Symposium Proceedings

  • DOI: https://doi.org/10.1007/978-3-662-09153-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1995

  • Softcover ISBN: 978-3-662-09155-5Published: 23 August 2014

  • eBook ISBN: 978-3-662-09153-1Published: 09 March 2013

  • Series ISSN: 0947-6075

  • Edition Number: 1

  • Number of Pages: XIV, 184

  • Number of Illustrations: 38 b/w illustrations

  • Topics: Internal Medicine, Human Genetics

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