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Transduction Mechanisms of Drug Stimuli

  • Book
  • © 1988

Overview

Editors:
  1. F. C. Colpaert

    1. FONDAX-Groupe de Recherches Servier, Puteaux, France

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  2. R. L. Balster

    1. Department of Pharmacology and Toxicology Medical College of Virginia, Virginia Commonwealth University, Richmond, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Psychopharmacology Series (PSYCHOPHARM, volume 4)

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-IX
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  2. Transduction

    1. Front Matter

      Pages 1-1
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    2. Drugs as Chemical Stimuli

      • R. L. Balster
      Pages 3-11

  3. Molecular Mechanisms

    1. Front Matter

      Pages 13-13
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    2. Site-Selective Serotonin Agonists as Discriminative Stimuli

      • R. A. Glennon
      Pages 15-31

    3. Discriminative Stimulus Effects of Cholinergic Agonists and the Actions of Their Antagonists

      • I. P. Stolerman, R. Kumar, C. Reavill
      Pages 32-43

    4. Stimulus Properties of Dopaminergic Drugs: Comparisons Involving Selective Agonists and Antagonists

      • J. B. Appel, R. T. Weathersby, K. A. Cunningham, P. M. Callahan, R. L. Barrett
      Pages 44-56

    5. Central Nervous System Stimulants: Neuropharmacological Mechanisms

      • E. B. Nielsen, J. Scheel-Krüger
      Pages 57-72

    6. Discriminative Stimulus Properties of Anxiolytic and Sedative Drugs: Pharmacological Specificity

      • D. J. Sanger
      Pages 73-84

    7. Comparison of Discriminative Stimuli Produced by Full and Partial Benzodiazepine Agonists: Pharmacological Specificity

      • D. A. Bennett
      Pages 85-94

    8. Receptor Mechanisms of Opioid Drug Discrimination

      • J. H. Woods, A. J. Bertalmio, A. M. Young, W. D. Essman, G. Winger
      Pages 95-106

    9. Discriminative and Analgesic Effects of Mu and Kappa Opioids: In Vivo pA2 Analysis

      • L. A. Dykstra, A. J. Bertalmio, J. H. Woods
      Pages 107-121

    10. Receptor Mediation of the Discriminative Stimulus Properties of Phencyclidine and Sigma-Opioid Agonists

      • R. L. Balster, J. Willetts
      Pages 122-135

  4. Theory, Concepts, and Research Strategies

    1. Front Matter

      Pages 137-137
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    2. Neural Mechanisms of Drug Stimuli: Experimental Approaches

      • S. G. Holtzman, K. W. Locke
      Pages 139-153

    3. Intrinsic Activity and Discriminative Effects of Drugs

      • F. C. Colpaert
      Pages 154-160

    4. Relationship Between the Discriminative Stimulus Properties and Subjective Effects of Drugs

      • C. R. Schuster, C. E. Johanson
      Pages 161-175

    5. Similarities and Differences Between Behavioral Control by Drug-Produced Stimuli and by Sensory Stimuli

      • D. A. Overton
      Pages 176-198

    6. Discrimination Strategies in Animal Psychophysics and Their Role in Understanding Sensory Receptor Function

      • W. C. Stebbins, D. W. Smith, D. B. Moody
      Pages 199-214

    7. Molecular Transduction Mechanisms in ACTH-Induced Grooming

      • W. H. Gispen, D. L. Colbern, B. M. Spruijt
      Pages 215-231
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Keywords

About this book

In this book the latest data available on transduction mechanisms of drug stimuli are presented. A common theme underlying the chapter in this volume is the recognition that drugs can act as stimuli, in much the same manner as external events do. Accordingly, the papers focus on the mechanisms by which these stimuli are transduced at different levels of analysis, such as the behavioral, pharmacological, and molecular levels. Some chapters discuss the mechanisms of transduction of the discriminative effects of several important classes of drugs, while others deal with the methods and research strategies by which these mechanisms can be analyzed. Collectively, the papers in this volume reflect the current status of knowledge in the rapidly expanding field of behavioral pharmacology.

Editors and Affiliations

  • FONDAX-Groupe de Recherches Servier, Puteaux, France

    F. C. Colpaert

  • Department of Pharmacology and Toxicology Medical College of Virginia, Virginia Commonwealth University, Richmond, USA

    R. L. Balster

Bibliographic Information

  • Book Title: Transduction Mechanisms of Drug Stimuli

  • Editors: F. C. Colpaert, R. L. Balster

  • Series Title: Psychopharmacology Series

  • DOI: https://doi.org/10.1007/978-3-642-73223-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-3-642-73225-6Published: 06 December 2011

  • eBook ISBN: 978-3-642-73223-2Published: 06 December 2012

  • Series ISSN: 0931-6795

  • Edition Number: 1

  • Number of Pages: IX, 236

  • Topics: Psychiatry, Pharmacology/Toxicology, Neurosciences

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