Mechanism of Action of Antibacterial Agents

1. Front Matter

   Pages I-XII

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2. Bacitracin

   • D. R. Storm, W. A. Toscano Jr.

   Pages 1-17

3. Bicyclomycin

   • N. Tanaka

   Pages 18-25

4. Chloramphenicol

   • O. Pongs

   Pages 26-42

5. Ethambutol

   • W. H. Beggs

   Pages 43-66

6. Ionophore Antibiotics

   • E. P. Bakker

   Pages 67-97

7. Isonicotinic Acid Hydrazide

   • K. Takayama, L. A. Davidson

   Pages 98-119

8. Kidamycin and Acetyl Kidamycin

   • H. Takeshima, I. Umezawa

   Pages 120-126

9. Lincomycin

   • F. N. Chang

   Pages 127-134

10. Moenomycin and Related Phosphorus-Containing Antibiotics

    • Gerhard Huber

    Pages 135-153

11. Nalidixic Acid

    • A. M. Pedrini

    Pages 154-175

12. Nitrofurans

    • D. R. McCalla

    Pages 176-213

13. Novobiocin and Coumermycin A1

    • M. J. Ryan

    Pages 214-234

14. Phenomycin and Enomycin

    • N. Tanaka

    Pages 235-242

15. Quinone Antibiotics

    • A. Ogilvie, W. Kersten

    Pages 243-263

16. Sparsomycin

    • I. H. Goldberg

    Pages 264-271

17. Streptomycin and Related Antibiotics

    • B. J. Wallace, P.-C. Tai, B. D. Davis

    Pages 272-303

18. Tetracycline

    • A. Kaji, M. Ryoji

    Pages 304-328

19. Thiostrepton and Related Antibiotics

    • E. Cundliffe

    Pages 329-343

20. Tiamulin and Pleuromutilin

    • G. Högenauer

    Pages 344-360

The first volume of Antibiotics was published in 1967 and contained a series of review papers on antibiotic actions. The editors, Drs. GOTTLIEB and SHAW, were aware of the rapid development of this field of study and provided a number of addenda in an effort to keep knowledge up to date while the book was in production. One year after the publication of Antibiotics I, this editor had a conference with Dr. KONRAD F. SPRINGER in which it became clear that another volume on actions of antibiotics would be necessary. For a variety of reasons, this was delayed until 1975 and became Antibiotics III. It did not contain addenda since it was recognized by the editors, Drs. CORCORAN and HAHN, that still another volume would have to follow and that in a moving field, such as the study of the actions of antibacterial drugs, no publication can be definitive or remain current, except for a limited period of time. The editors of Volume III grouped the contributions into sections: 1. Inter­ ference with nucleic acid biosyntheses, 2. Interference with protein biosynthesis, and 3. Interference with cell wall/membrane biosynthesis, specific enzyme sys­ tems, and those in which the mode of action was not known with certainty.

• Antibiotikum
• Biosynthese
• Chemotherapeutikum
• antibiotic
• bacteria
• cell
• enzyme
• protein
• research

• Department of the Army, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, USA

  Fred E. Hahn

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