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Glycans in Diseases and Therapeutics

  • Book
  • © 2011

Overview

  • Provides timely reviews on current topics of ECM biology.-
  • Improves our understanding of the cellbiological background of diseases.-
  • Published in collaboration with the American Society for Matrix Biology.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Biology of Extracellular Matrix (BEM)

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Table of contents (7 chapters)

Keywords

About this book

Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.

This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.

Editors and Affiliations

  • , Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Mauro S.G. Pavão

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