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Biologie und Epidemiologie der Hormonersatztherapie - Biology and Epidemiology of Hormone Replacement Therapy

Diskussionen zur Postmenopausalen Gesundheit - Discussions on Post-Menopausal Health

  • Conference proceedings
  • © 2006

Overview

Editors:
  1. M. A. Lewis

    1. EPES Epidemiologie, Pharmakoepidemiologie, und Systemforschung GmbH, Berlin, Germany

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  2. M. Dietel

    1. Charité — Institut für Pathologie, Berlin, Germany

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  3. P. C. Scriba

    1. Medizinische Klinik Innenstadt, Ludwig-Maximilians-Universität München, Munich, Germany

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  4. W. K. Raff

    1. Berlin, Germany

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  • Diskussion der Vor- und Nachteile der Hormonerstatztherapie
  • Schwerpunkt der Diskussion ist Bruskrebsrisiko
  • Contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT)
  • Addresses all aspects and risks associated with HRT
  • Provides detailed review of controversy
  • Includes supplementary material: sn.pub/extras

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 13)

Part of the book sub series: Schering Foundation Symposium Proceedings Supplements (3368)

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Table of contents (15 papers)

  1. Front Matter

    Pages I-XV
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  2. The Presentations

    1. Front Matter

      Pages 1-1
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    2. Introduction to the Presentations

      • M. A. Lewis
      Pages 3-4

    3. Women Between Biology and Civilization

      • A. Teichmann
      Pages 5-17

    4. Issues with the Term “Responsibility”

      • H. Poser
      Pages 19-46

    5. Epidemiology of Selected Diseases in Women

      • L. Heinemann
      Pages 47-54

    6. Pathogenesis of Histological Types of Endometrial Cancer

      • L. -C. Horn
      Pages 55-62

    7. Pathology of the Colon and Ovary

      • M. Dietel
      Pages 63-69

    8. The Progenitor Cell Concept of Proliferative Breast Disease

      • W. Böcker
      Pages 71-80

    9. Indication for HRT: Climacteric Complaints and Osteoporosis

      • H. P. G. Schneider
      Pages 81-102

    10. HRT and Cardiovascular Disease in Women

      • E. Windler
      Pages 103-119

    11. The Million Women Study

      • O. Lidegaard
      Pages 121-126

    12. Paradigm Shift in Causal Thinking in Epidemiology

      • S. Shapiro
      Pages 127-133

    13. Perception and Communication of Risk

      • K. Heilmann
      Pages 135-143

    14. Some Thoughts After the Kloster Andechs Workshop, August 2003

      • U. Karck
      Pages 145-148

  3. The General Discussion

    1. Front Matter

      Pages 149-149
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    2. Menopause and the HRT Risk — Benefit Equation: Status and Outlook

      Pages 151-163

  4. Conclusions of the Kloster Andechs Workshop

    1. Front Matter

      Pages 165-165
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    2. Workshop Consensus: The State of the Evidence

      Pages 167-173

  5. Back Matter

    Pages 175-179
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Keywords

About this book

Die Vor- und Nachteile der Hormonersatztherapie (HRT) werden von einer Expertengruppe hinsichtlich der epidemiologischen Beweislage diskutiert. Obwohl alle positiven und negativen Aspekte der HRT behandelt werden, liegt der Schwerpunkt der Diskussionen bei der Frage des Brustkrebsrisikos. Unter anderem wird gezeigt, dass die aus epidemiologischen Studien abgeleiteten Ergebnisse sich nicht mit den Wachstumseigenschaften dieser Tumoren decken so dass weiterführende Bevölkerungsuntersuchungen unter Einbeziehungen pathobiologischen Sachverstands notwendig erscheinen.

This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of the current evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT, including issues concerning psychology, the cardiovascular system, bone structure, and carcinogenesis. It focuses, however, on cancer risk and on risk of breast cancer in particular. In doing so, it provides a detailed discussion of the pathobiological features of breast cancer, concluding that the evidence provided by epidemiological studies is in conflict with the biological growth features of breast cancer. It advocates further epidemiological studies which incorporate pathobiological assessments.

Editors and Affiliations

  • EPES Epidemiologie, Pharmakoepidemiologie, und Systemforschung GmbH, Berlin, Germany

    M. A. Lewis

  • Charité — Institut für Pathologie, Berlin, Germany

    M. Dietel

  • Medizinische Klinik Innenstadt, Ludwig-Maximilians-Universität München, Munich, Germany

    P. C. Scriba

  • Berlin, Germany

    W. K. Raff

Bibliographic Information

  • Book Title: Biologie und Epidemiologie der Hormonersatztherapie - Biology and Epidemiology of Hormone Replacement Therapy

  • Book Subtitle: Diskussionen zur Postmenopausalen Gesundheit - Discussions on Post-Menopausal Health

  • Editors: M. A. Lewis, M. Dietel, P. C. Scriba, W. K. Raff

  • Series Title: Ernst Schering Foundation Symposium Proceedings

  • DOI: https://doi.org/10.1007/978-3-540-37861-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2006

  • Hardcover ISBN: 978-3-540-32341-9Published: 25 July 2006

  • Softcover ISBN: 978-3-642-42162-4Published: 26 November 2014

  • eBook ISBN: 978-3-540-37861-7Published: 24 May 2007

  • Series ISSN: 0947-6075

  • Edition Number: 1

  • Number of Pages: XV, 179

  • Topics: Gynecology, Epidemiology, Oncology, Pathology

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