The Mediastinal Mass

1. Front Matter

   Pages i-xii

   PDF

2. Mediastinum Masses

   1. Front Matter

      Pages 1-1

      PDF

   2. Introduction (Epidemiology, Mediastinal Anatomy, Mediastinal Masses)

      • Gerardo Botti, Federica Zito Marino

      Pages 3-6

   3. Clinical Approach: Recommendations for the Clinicians

      • Fortunato Ciardiello, Floriana Morgillo, Giuseppe Viscardi

      Pages 7-15

   4. Mediastinal Masses: Radiological Point of View

      • Alfonso Reginelli, Anna Russo, Fernando Scala, Elisa Micheletti, Roberta Grassi, Mario Santini et al.

      Pages 17-34

   5. Radiotherapy in Anterior Mediastinum Cancers

      • Alfonso Reginelli, Anna Russo, Fernando Scala, Elisa Micheletti, Roberta Grassi, Mario Santini et al.

      Pages 35-41

   6. Surgery: Recommendations for Surgeons

      • Mario Santini, Alfonso Fiorelli

      Pages 43-64

   7. Diagnostic Histopathology Approach

      • Giulio Rossi, Moira Ragazzi, Alberto Cavazza

      Pages 65-127

   8. Thymic Tumors and Lymphomas: The Clinical Impact of Their Underlying Molecular Features

      • Francesca Pentimalli, Daniela Barone, Antonio Giordano

      Pages 129-161

   9. Therapy: Recommendations for the Oncologists

      • Francesco Facchinetti, Letizia Gnetti, Marcello Tiseo

      Pages 163-169

3. Anterior Mediastinum Masses

   1. Front Matter

      Pages 171-171

      PDF

   2. Thymic Neoplasm

      • Mirella Marino, Francesco Facciolo, Yan Shen, Gabriele Alessandrini, Nicolas Girard

      Pages 173-214

   3. Primitive Mediastinal Germ Cell Tumors: An Update

      • Andrea Ronchi, Federica Zito Marino, Gaetano Facchini, Marina Accardo, Renato Franco

      Pages 215-227

   4. Thyroid

      • Maria Grazia Chiofalo, Sergio Venanzio Setola, Fabio Sandomenico, Orlando Catalano, Raffaella D’Anna, Paolo Vallone et al.

      Pages 229-234

   5. Parathyroid

      • Maria Grazia Chiofalo, Sergio Venanzio Setola, Fabio Sandomenico, Orlando Catalano, Raffaella D’Anna, Paolo Vallone et al.

      Pages 235-239

   6. Mediastinal Lymphoma

      • Miguel A. Piris, Jorge Muñoz, Socorro M. Rodríguez-Pinilla

      Pages 241-249

4. Middle Mediastinum Masses

   1. Front Matter

      Pages 251-251

      PDF

   2. Granulomatous Disease

      • Nicola Martucci, Giuseppe De Luca, Gaetano Rocco

      Pages 253-260

   3. Cysts of the Middle Mediastinum

      • Giuseppe De Luca, Nicola Martucci, Gaetano Rocco

      Pages 261-269

   4. Tracheal Tumors

      • Giuseppe De Luca, Nicola Martucci, Gaetano Rocco

      Pages 271-276

Tumors of the mediastinum are usually diagnosed in young patients, but they can develop at any age and form any tissue that exists in or passes through the chest cavity. The diagnosis and the accurate assessment of the mediastinum masses represents a challenge, given their clinical variability from asymptomatic to producing symptoms of cough, chest pain, and dyspnea. Mediastinal tumors encompass a wide range of various neoplasms. The localization of mediastinal masses is critical in the diagnosis: the anterior mediastinal masses are generally thymomas, teratomas, substernal thyroid/parathyroid tissue, or lymphomas; the middle mediastinum massess are typically pericardial and bronchogenic cysts; the posterior mediastinum  masses are often neurogenic tumors and esophageal cysts. The wide variety of different entities demonstrates a heterogeneous spectrum of clinical and pathologic features, suggesting that a uniform “standard” management of these patients is not appropriate.   


In this context, the proposed book will provide a comprehensive review of the mediastinal tumors according to different sites of the diseases, including the masses of anterior, middle and posterior mediastinum. The handling of these tumors requires a multidisciplinary approach due to the complex anatomy of the mediastinum as well as the different clinical, radiographic, and prognostic features. This book has risen from the desire to provide to the specialists in the field an easy, updated and practical guidelines title to facilitate the clinical practice of mediastinic masses. This book will be a comprehensive guide to clinical best practices developed through the opinions of experts in the field.

• Thymic Neoplasm
• Germ Cell Tumors
• Lymphoma
• Granulomatous disease
• Tracheal tumors
• Nerve Sheath Tumors
• Esophageal Tumors
• thoracic surgery

“This is a well‐organized, visually appealing, relatively quick‐to‐read resource meant for a wide audience, including pathologists, oncologists, radiologists, and surgeons. … it does effectively communicate the necessary perspectives. I especially recommend this book for practicing clinicians, as it provides a succinctupdate to the ever‐evolving diagnosis and management of mediastinal masses.” (Anna B Owczarczyk, Doody's Book Reviews, June 07, 2019)​

• Pathology Unit, Department of Mental and Physic Health and Preventive Medicine, Università della Campania ‘Luigi Vanvitelli’, Naples, Italy

  Renato Franco, Federica Zito Marino

• Sbarro Institute for Cancer Research, Temple University Sbarro Institute for Cancer Research, Philadelphia, USA

  Antonio Giordano

Renato Franco, MD, PhD
Associate Professor
Pathology Unit
Mental and Physic Health and Preventive Medicine Dpt
Università della Campania Luigi Vanvitelli
Napoli, Italy
 
Federica Zito Marino, BD
Pathology Unit
Mental and Physic Health and Preventive Medicine Dpt
Università della Campania Luigi Vanvitelli
Napoli, Italy
 
Antonio Giordano MD, PhD  
Director Sbarro Institute for Cancer Research and Molecular Medicine and Center of Biotechnology   
College of Science and Technology
Temple University 
Philadelphia, PA
USA

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