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Haploidentical Stem Cell Transplantation

An Emerging Treatment Modality

Editors:

  • Authors are worldwide experts in the field and provide international perspectives and expertise
  • A rapidly developing modality; this topic has not yet appeared in many books but mostly in journal articles
  • Comprehensive yet succinct treatment of the topic; enables readers to get up to speed quickly

Part of the book series: Stem Cell Biology and Regenerative Medicine (STEMCELL)

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Softcover Book USD 109.99
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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xv
  2. General Indications and Logic for Haploidentical SCT

    • Florent Malard, Mohamad Mohty
    Pages 1-7
  3. Donor Selection and Cell Dose in Haploidentical SCT

    • Riad El Fakih, Mutlu Arat, Mahmoud Aljurf
    Pages 9-16
  4. Graft Failure and Rejection in Haploidentical Stem Cell Transplantation

    • Miguel Blanquer, Jose M. Moraleda
    Pages 17-41
  5. Toxicity of Conditioning Regimens in Haploidentical SCT

    • Meltem Kurt Yüksel, Taner Demirer
    Pages 43-56
  6. Prevention and Treatment of Infectious Complications in Haploidentical SCT

    • Angela Haßler, Thomas Lehrnbecher, Peter Bader, Thomas Klingebiel
    Pages 67-93
  7. Graft Versus Leukemia (GvL), Graft Versus Lymphoma Effect in Haploidentic SCT

    • Jakob R. Passweg, Michael Medinger, Joerg P. Halter
    Pages 95-102
  8. Outcome of Haploidentical SCT in Patients with Acute Leukemia

    • Albert Esquirol, Jorge Sierra
    Pages 103-117
  9. Applications of Haploidentical SCT in Pediatric Patients

    • Marco Zecca, Patrizia Comoli
    Pages 149-178
  10. Innovative Approaches to Increase the Success of the Haploidentical SCT

    • Ulas D. Bayraktar, Stefan O. Ciurea
    Pages 179-187
  11. Future Perspectives for Haploidentical SCT

    • Ugur Sahin, Taner Demirer
    Pages 189-199

About this book

This book discusses the aspects of haploidentical transplants and will shed light on the debates and questions on this burgeoning field and timely topic. Donor selection, graft failure, minimal CD34+ cell requirement, and conditioning regimens used for haploidentical transplants will be written by expert authors dealing with this type of transplants. Approximately one third of the books' chapters cover logic and basic aspects; the remaining two thirds of the book discuss clinical aspects, outcomes, and future perspectives, thus providing a comphrensive discussion of the topic. Haploidentical transplantation is extremely timely, rapidly-changing area and increasing its use will decrease the need for time-consuming, expensive, unrelated donor search. Moreover, Haploidentical Stem Cell Transplantation brings a set of clear answers to questions of feasibility, advantages over unrelated transplants, cost effectivity and outcome.. 

Editors and Affiliations

  • Department of Hematology, Ankara University Medical School, Sıhhiye, Turkey

    Taner Demirer

About the editor

Dr. Taner Demirer, MD, FACP, graduated from Ankara University Medical School in Turkey in 1984 and was trained in the USA through 1987-1997.  He completed his Internal Medicine residency at the Medical College of Wisconsin in 1989-1992 and hematology/oncology and bone marrow transplant fellowship at the University of Washington, Fred Hutchinson Cancer Research Center (FHCRC) in Seattle, in 1992-1997. He was trained under Professors Don Thomas (Nobel laureate), Dean Buckner, Frederick Appelbaum and Rainer Storb in the clinical division of FHCRC.   He is a diplomate of the American Board of Internal Medicine and Board certified in Internal Medicine and Medical Oncology.  He was given the title of ‘Fellow of American College of Physicians (FACP) by ACP in July 1996.  He has conducted many clinical studies at the FHCRC  as principal investigator or co-investigator mainly related to peripheral blood stem cell (PBSC)  mobilization and high-dosechemotherapy (HDC) as well as autologous or allogeneic stem cell transplantations (SCT) in patients with solid tumors and hematologic malignancies.  During his career he has written many papers in the respected medical journals and books in regard to PBSC mobilization kinetics, factors influencing the PBSC collection and engraftment and allogeneic as well as autologous SCT in patients with hematologic malignancies and solid tumors.  He was chairman of the EBMT Solid Tumors Working Party (STWP) in between 2001-2007. He has conducted, chaired and published studies in related to HDC in patients with solid tumors at the EBMT STWP.  He was also board member of the Federation of the European Cancer Societies (FECS) on behalf of the EBMT through 2001-2007.  He was the president of the 29th and 41st EBMT Annual Meetings which were held in Istanbul in 2003 and 2015. He has been member of the editorial board of several international journals.  Dr. Demirer is ,currently, a professor of medicine and hematology/oncology at the Ankara University Medical School in Ankara, Turkey, and a full member of the Turkish Academy of Sciences as well as the European Academy of Sciences and Arts (EASA).        

Bibliographic Information

  • Book Title: Haploidentical Stem Cell Transplantation

  • Book Subtitle: An Emerging Treatment Modality

  • Editors: Taner Demirer

  • Series Title: Stem Cell Biology and Regenerative Medicine

  • DOI: https://doi.org/10.1007/978-3-319-65319-8

  • Publisher: Humana Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-65318-1Published: 08 November 2017

  • Softcover ISBN: 978-3-319-87999-4Published: 12 June 2018

  • eBook ISBN: 978-3-319-65319-8Published: 27 October 2017

  • Series ISSN: 2196-8985

  • Series E-ISSN: 2196-8993

  • Edition Number: 1

  • Number of Pages: XV, 199

  • Number of Illustrations: 12 b/w illustrations, 15 illustrations in colour

  • Topics: Stem Cells, Hematology, Oncology, Cancer Research

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access