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Current Strategies in Cancer Gene Therapy

  • Book
  • © 2016

Overview

Editors:
  1. Wolfgang Walther

    1. Department of Translational Oncology, Experimental and Clinical Research Center, Charité University Medicine Berlin and Max-Delbrück-Center for Molecular Medicine, Berlin, Germany

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  • Provides a broad overview of current developments in gene therapy
  • Includes novel approaches in cancer gene therapy
  • Links experimental strategies and their clinical applications
  • Includes supplementary material: sn.pub/extras

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 209)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-v
    Download chapter PDF

  2. p53 Replacement Therapy for Cancer

    • Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
    Pages 1-15

  3. Retroviral Vectors for Cancer Gene Therapy

    • Axel Schambach, Michael Morgan
    Pages 17-35

  4. Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells

    • Michael Hudecek, Tea Gogishvili, Razieh Monjezi, Julia Wegner, Ram Shankar, Christa Kruesemann et al.
    Pages 37-50

  5. Noncoding RNA for Cancer Gene Therapy

    • Xiaomin Zhong, Dongmei Zhang, Minmin Xiong, Lin Zhang
    Pages 51-60

  6. mRNA Cancer Vaccines

    • Katja Fiedler, Sandra Lazzaro, Johannes Lutz, Susanne Rauch, Regina Heidenreich
    Pages 61-85

  7. Gene Therapeutic Approaches to Overcome ABCB1-Mediated Drug Resistance

    • Hermann Lage
    Pages 87-94

  8. Bacterial Toxins for Oncoleaking Suicidal Cancer Gene Therapy

    • Jessica Pahle, Wolfgang Walther
    Pages 95-110

  9. Use of Bacteria in Cancer Therapy

    • Pooja Sarotra, Bikash Medhi
    Pages 111-121
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Keywords

About this book

This book describes important developments and emerging trends in experimental and clinical cancer gene therapy. It reflects the tremendous advances made over recent years with respect to immunogenes, suicide genes and gene correction therapies, as well as in gene suppression and miRNA therapies. Many of the described strategies focus on the generation of more efficient and specific means of attack at known and novel cellular targets associated with tumor development and progression. The book also details parallel improvements in vector design, vector delivery, and therapeutic efficacy. It offers readers a stimulating, broad overview of advances in the field, linking experimental strategies to their clinical applications.

Editors and Affiliations

  • Department of Translational Oncology, Experimental and Clinical Research Center, Charité University Medicine Berlin and Max-Delbrück-Center for Molecular Medicine, Berlin, Germany

    Wolfgang Walther

Bibliographic Information

  • Book Title: Current Strategies in Cancer Gene Therapy

  • Editors: Wolfgang Walther

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-319-42934-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-42932-8Published: 25 January 2017

  • Softcover ISBN: 978-3-319-82697-4Published: 12 July 2018

  • eBook ISBN: 978-3-319-42934-2Published: 17 January 2017

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: V, 121

  • Number of Illustrations: 6 b/w illustrations, 7 illustrations in colour

  • Topics: Oncology, Cancer Research, Gene Therapy

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