Overview
- Broadens your understanding TCTP's role in various diseases
- Illustrates the various interactions of TCTP with other Proteins
- Reviews the history of TCTP research
- New target and novel approach in cancer treatment
Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 64)
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Table of contents (16 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis.
In turn, the book’s final section is devoted to the role of TCTP in disease, namely asthma and diverse cancers, and ultimately as a target for the treatment of malignancies. What is the common denominator between all these processes and why is TCTP necessary in order for them to occur, even in the worst case such as cancer? The book seeks to provide meaningful answers to this and other key questions. Presenting a broad and revealing view on the topic, it offers an informative guide for scientists and students alike.
Editors and Affiliations
Bibliographic Information
Book Title: TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease
Editors: Adam Telerman, Robert Amson
Series Title: Results and Problems in Cell Differentiation
DOI: https://doi.org/10.1007/978-3-319-67591-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-67590-9Published: 28 November 2017
Softcover ISBN: 978-3-319-88453-0Published: 23 May 2018
eBook ISBN: 978-3-319-67591-6Published: 17 November 2017
Series ISSN: 0080-1844
Series E-ISSN: 1861-0412
Edition Number: 1
Number of Pages: X, 309
Number of Illustrations: 15 b/w illustrations, 36 illustrations in colour
Topics: Cancer Research, Protein Structure, Stem Cells, Cell Cycle Analysis, Apoptosis