Biomarkers for Endometriosis

State of the Art

Editors: D'Hooghe, Thomas M. (Ed.)

  • Summarizes the latest diagnostic performance of non- or semi-invasive tests for endometriosisReviews the key current research and developments of biomarkers in related fields
  • Explores the future developments necessary to create a successful non-invasive test for endometriosis  
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eBook 107,09 €
price for Spain (gross)
  • ISBN 978-3-319-59856-7
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  • Immediate eBook download after purchase
Hardcover 140,39 €
price for Spain (gross)
  • ISBN 978-3-319-59854-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This book presents an overview of the diagnostic performance of non- or semi-invasive tests for endometriosis in peripheral blood, endometrium, saliva, peritoneal fluid and urine. The value of existing and emerging systems biology technologies for biomarker development is addressed in several chapters on genetics, microarrays, proteomics and metabolomics. Although tests with high sensitivity and acceptable specificity have been developed, sometimes validated in independent populations and seem promising, more research is needed to translate these data into clinical benefit for patients and coordinate efforts internationally to standarize analysis, reports and operating procedures. The gold standard to diagnose endometriosis is currently through laparoscopic inspection with histological confirmation, a surgical procedure with rare but significant potential risks for the patients. A non-invasive test for endometriosis would be critical for the early detection of endometriosis of symptomatic women with pelvic pain and/or subfertility with normal ultrasound. This would include nearly all cases of minimal-mild endometriosis, some cases of moderate-severe endometriosis without a clearly visible ovarian endometrioma and cases with pelvic adhesions and/or other pelvic pathology, who might benefit from surgery to improve pelvic pain and/or subfertility. Such a test would also be useful in symptomatic women with ultrasound imaging suspicious for endometriosis, since it may be difficult to differentiate an ovarian endometrioma from other ovarian cysts and since the quality of ultrasound imaging is highly variable worldwide.

About the authors

Thomas M. D’Hooghe is Professor of Reproductive Medicine in the Deparment of  Development and Regeneration of the Biomedical Sciences Group at KU Leuven (University of Leuven), Belgium. Dr. D’Hooghe is also Professor Adjunct, Department of Obstetrics, Gynecology and Reproductive Medicine, Yale University Medical School, New Haven, Connecticut, USA, and Editor-in-Chief of Gynecologic and Obstetric Investigation,Basel, since 2002. Since October 2015, Professor D’Hooghe is the Vice-President and Head of Global Medical Affairs Fertility in the Department of Research and Development at Merck KGaA, Darmstadt, Germany.

Table of contents (12 chapters)

  • Building Translational Research Infrastructure and Access to Expertise for Biomarker Discovery in Cancer

    Hall, Jacqueline A.

    Pages 1-25

    Preview Buy Chapter 30,19 €
  • Biomarkers of Endometrial Cancer

    Galazis, Nicholas

    Pages 27-39

    Preview Buy Chapter 30,19 €
  • Biomarker Development in Chronic Inflammatory Diseases

    Katsanos, Aristeidis H. (et al.)

    Pages 41-75

    Preview Buy Chapter 30,19 €
  • Endometriosis and Diagnostic Delay: The Patient’s Perspective

    Apers, Silke (et al.)

    Pages 77-82

    Preview Buy Chapter 30,19 €
  • Genetic Biomarkers for Endometriosis

    Lee, Sang Hong (et al.)

    Pages 83-93

    Preview Buy Chapter 30,19 €

Buy this book

eBook 107,09 €
price for Spain (gross)
  • ISBN 978-3-319-59856-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 140,39 €
price for Spain (gross)
  • ISBN 978-3-319-59854-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Biomarkers for Endometriosis
Book Subtitle
State of the Art
Editors
  • Thomas M. D'Hooghe
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-59856-7
DOI
10.1007/978-3-319-59856-7
Hardcover ISBN
978-3-319-59854-3
Edition Number
1
Number of Pages
XII, 267
Number of Illustrations and Tables
5 b/w illustrations, 3 illustrations in colour
Topics