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Managing BRCA Mutation Carriers

  • Book
  • © 2017

Overview

Editors:
  1. Anees B. Chagpar

    1. Yale Comprehensive Cancer Center, Yale University School of Medicine Yale Comprehensive Cancer Center, New Haven, USA

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  • Provides a comprehensive, state-of-the art review of this field

  • Presents a multidisciplinary approach gleaning insights from many disciplines

  • Written by experts in their fields

  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xi
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  2. Risk Assessment for Breast Cancer

    • Anvy Nguyen, Jessica Cintolo-Gonzalez, Jennifer K. Plichta, Kevin S. Hughes
    Pages 1-14

  3. Genetic Evaluation for Women at Increased Risk

    • Karina L. Brierley, Claire L. Healy, Erin W. Hofstatter
    Pages 15-30

  4. Imaging Screening and Surveillance

    • Ellen Warner
    Pages 31-45

  5. Risk-Reducing Surgery for BRCA1/2 Genetic Mutation Carriers

    • Cristina O’Donoghue, Sonia Orcutt, Tuya Pal, Christine Laronga
    Pages 47-63

  6. Prophylactic Oophorectomy for Patients with Germline BRCA Mutations

    • Dario R. Roque, Don S. Dizon
    Pages 65-87

  7. Pathology of BRCA Tumors

    • Julio A. Ibarra
    Pages 89-117

  8. Surgical Management of Breast Cancer in BRCA Mutation Carriers

    • Patricia A. Cronin, Hiram S. Cody III
    Pages 119-134

  9. Medical Management of Breast Cancer in BRCA Mutation Carriers

    • Soley Bayraktar, Banu K. Arun
    Pages 135-150

  10. Radiation Oncology Considerations in the Management of Mutation Carriers with Breast Cancer

    • Meena S. Moran
    Pages 151-170

  11. Fertility Preservation in BRCA Carriers: Special Considerations

    • Iris G. Insogna, Elizabeth S. Ginsburg, Ann H. Partridge
    Pages 171-186

  12. Management of Male BRCA Mutation Carriers

    • Donna-Marie Manasseh, Ryland J. Gore, Patrick I. Borgen
    Pages 187-203

  13. Psychosocial, Ethical, and Legal Implications for Mutation Carriers

    • Jacquelyn M. Powers, Jessica M. Long, Willonie Mendonca
    Pages 205-234

  14. Back Matter

    Pages 235-242
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Keywords

About this book

As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.



Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.


Editors and Affiliations

  • Yale Comprehensive Cancer Center, Yale University School of Medicine Yale Comprehensive Cancer Center, New Haven, USA

    Anees B. Chagpar

About the editor

Anees B. Chagpar, MD, MSc, MPH, MA, MBA, FRCS(C), FACS
Associate Professor, Department of Surgery
Director, The Breast Center -- Smilow Cancer Hospital at Yale-New Haven
Assistant Director -- Global Oncology, Yale Comprehensive Cancer Center
Yale University School of Medicine
20 York Street, First floor Suite A
New Haven, CT 06510
Phone:  203-200-1518




Bibliographic Information

  • Book Title: Managing BRCA Mutation Carriers

  • Editors: Anees B. Chagpar

  • DOI: https://doi.org/10.1007/978-3-319-59198-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-59197-1Published: 24 July 2017

  • Softcover ISBN: 978-3-319-86566-9Published: 09 September 2018

  • eBook ISBN: 978-3-319-59198-8Published: 13 July 2017

  • Edition Number: 1

  • Number of Pages: XI, 242

  • Number of Illustrations: 3 b/w illustrations, 21 illustrations in colour

  • Topics: Surgical Oncology, Pathology, Oncology, Human Genetics

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