Overview
- Editors:
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Richard Bucala
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The Anlyan Center, Yale School of Medicine, Yale University, New Haven, USA
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Jürgen Bernhagen
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Department of Vascular Biology, Institute for Stroke and Dementia Research, Ludwig-Maximilians-University (LMU), Munich, Germany
- Provides a comprehensive synthesis of the state-of-the-art of MIF science
- Covers role of MIF in immunopathogenesis of different inflammatory, autoimmune, and infectious diseases
- Provides outlook on MIF-directed therapies
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Table of contents (14 chapters)
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Front Matter
Pages i-viii
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- Shirly Becker-Herman, Naama Gil, Lihi Radomir, Idit Shachar
Pages 1-20
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- Ramona Schulz-Heddergott, Ute M. Moll
Pages 21-42
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- Kavitha Yaddanapudi, Robert A. Mitchell
Pages 59-76
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- Saisha A. Nalawade, Yousef Al-Abed, Thomas G. Forsthuber
Pages 77-95
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- Gil Benedek, Roberto Meza-Romero, Arthur A. Vandenbark
Pages 97-107
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- Veronica Marin, Gemma Odena, Kyle Poulsen, Claudio Tiribelli, Stefano Bellentani, Andrea Barchetti et al.
Pages 109-134
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- Timothy Baker, Patty J. Lee, Maor Sauler
Pages 135-144
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- Fei Ma, Katherine L. Meyer-Siegler, Karin N. Westlund, Pedro L. Vera
Pages 145-155
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- Christian Stoppe, Jürgen Bernhagen
Pages 157-174
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- Lara J. Herrero, Ali Zaid, Margit Mutso, Suresh Mahalingam
Pages 175-187
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- Marcelo T. Bozza, Claudia N. Paiva, Priscilla C. Olsen
Pages 189-202
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- Cesar Terrazas, James C. Stock, Jeniffer Kimble, Ellen Moretti, Sanjay Varikuti, Abhay R. Satoskar
Pages 203-219
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- Thomas Holowka, Richard Bucala
Pages 221-239
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Back Matter
Pages 241-246
About this book
The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress responses. MIF’s molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. New family members, such as D-dopachrome tautomerase, or MIF-2, and the closely homologous genes encoding by parasites have been defined and are being functionally characterized. MIF directed therapies also are entering clinical testing and ultimately may be applied in a pharmacogenomics manner. This book provides a comprehensive synthesis of the state-of-the-art of MIF science. The intended audience are post-graduate students and researchers in inflammation, innate immunity, immunology, and immunopathology.
Editors and Affiliations
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The Anlyan Center, Yale School of Medicine, Yale University, New Haven, USA
Richard Bucala
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Department of Vascular Biology, Institute for Stroke and Dementia Research, Ludwig-Maximilians-University (LMU), Munich, Germany
Jürgen Bernhagen
About the editors
Richard Bucala, MD PhD; Professor of Medicine, Pathology, and Epidemiology & Public Health at Yale University, School of Medicine, New Haven, CT, USA Jürgen Bernhagen, PhD; Institute of Biochemistry and Molecular Cell Biology, Universitätsklinikum Aachen, RWTH Aachen, Germany
