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  • © 2017

Computational Neurology and Psychiatry

  • Reports on computational studies of brain and mind disease
  • Describes computational models and their use in practice
  • Includes background information on the biology of the diseases
  • With take-home messages for both neurologists and computer scientists
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Series in Bio-/Neuroinformatics (SSBN, volume 6)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-vi
  2. Introduction

    • Basabdatta Sen Bhattacharya, Amy L. Cochran, Péter Érdi
    Pages 1-10
  3. Outgrowing Neurological Diseases: Microcircuits, Conduction Delay and Childhood Absence Epilepsy

    • John Milton, Jianhong Wu, Sue Ann Campbell, Jacques Bélair
    Pages 11-47
  4. Extracellular Potassium and Focal Seizures—Insight from In Silico Study

    • Piotr Suffczynski, Damiano Gentiletti, Vadym Gnatkovsky, Marco de Curtis
    Pages 49-72
  5. Time Series and Interactions: Data Processing in Epilepsy Research

    • Zsigmond Benkő, Dániel Fabó, Zoltán Somogyvári
    Pages 73-91
  6. Dynamic Causal Modelling of Dynamic Dysfunction in NMDA-Receptor Antibody Encephalitis

    • Richard E. Rosch, Gerald Cooray, Karl J. Friston
    Pages 121-148
  7. Oscillatory Neural Models of the Basal Ganglia for Action Selection in Healthy and Parkinsonian Cases

    • Robert Merrison-Hort, Nada Yousif, Andrea Ferrario, Roman Borisyuk
    Pages 149-189
  8. Mathematical Models of Neuromodulation and Implications for Neurology and Psychiatry

    • Janet A. Best, H. Frederik Nijhout, Michael C. Reed
    Pages 191-225
  9. Attachment Modelling: From Observations to Scenarios to Designs

    • Dean Petters, Luc Beaudoin
    Pages 227-271
  10. A Comparison of Mathematical Models of Mood in Bipolar Disorder

    • Amy L. Cochran, André Schultz, Melvin G. McInnis, Daniel B. Forger
    Pages 315-341
  11. Computational Neuroscience of Timing, Plasticity and Function in Cerebellum Microcircuits

    • Shyam Diwakar, Chaitanya Medini, Manjusha Nair, Harilal Parasuram, Asha Vijayan, Bipin Nair
    Pages 343-371
  12. A Computational Model of Neural Synchronization in Striatum

    • Rahmi Elibol, Neslihan Serap Şengör
    Pages 373-403
  13. The Role of Simulations in Neuropharmacology

    • Jean-Marie C. Bouteiller, Theodore W. Berger
    Pages 429-448

About this book

This book presents the latest research in computational methods for modeling and simulating brain disorders. In particular, it shows how mathematical models can be used to study the relationship between a given disorder and the specific brain structure associated with that disorder. It also describes the emerging field of computational psychiatry, including the study of pathological behavior due to impaired functional connectivity, pathophysiological activity, and/or aberrant decision-making. Further, it discusses the data analysis techniques that will be required to analyze the increasing amount of data being generated about the brain. Lastly, the book offers some tips on the application of computational models in the field of quantitative systems pharmacology. Mainly written for computational scientists eager to discover new application fields for their model, this book also benefits neurologists and psychiatrists  wanting to learn about new methods.

Editors and Affiliations

  • Department of Physics, Kalamazoo College, Kalamazoo, USA

    Péter Érdi

  • School of Engineering, University of Lincoln, Lincoln, United Kingdom

    Basabdatta Sen Bhattacharya

  • Department of Mathematics, University of Michigan, Ann Arbor, USA

    Amy L. Cochran

Bibliographic Information

Buy it now

Buying options

eBook USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access