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Protein Toxins in Modeling Biochemistry

  • Book
  • © 2016

Overview

Authors:
  1. Raj Kumar

    1. Institute of Advanced Sciences, North Dartmouth, USA

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    You can also search for this author in PubMed   Google Scholar

  2. Bal Ram Singh

    1. Institute of Advanced Sciences, North Dartmouth, USA

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    You can also search for this author in PubMed   Google Scholar

  • Addresses a newly-emerging concept of molten globule playing a critical role in protein folding and function
  • Provides information on flexible dynamic targeting compared to current molecular docking based on the static structures which will be extremely useful in drug development
  • Presents an extremely useful model for studying various aspects of protein chemistry

Part of the book series: SpringerBriefs in Biochemistry and Molecular Biology (BRIEFSBIOCHEM)

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Table of contents (5 chapters)

  1. Front Matter

    Pages i-xix
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  2. Introduction

    • Raj Kumar, Bal Ram Singh
    Pages 1-4

  3. Introduction to Protein Folding

    • Raj Kumar, Bal Ram Singh
    Pages 5-28

  4. Relevance of Intrinsic Disorder in Protein Structure and Function

    • Thomas M. Feltrup, Raj Kumar, Bal Ram Singh
    Pages 29-72

  5. Implication of Molten Globule on the Function and Toxicity of a Protein

    • Harkiran Preet Kaur Dhaliwal, Raj Kumar, Bal Ram Singh
    Pages 73-112

  6. Evolution of Toxin

    • Raj Kumar, Bal Ram Singh
    Pages 113-134

  7. Back Matter

    Pages 135-145
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Keywords

About this book

This succinct volume addresses the production of inactive, potentially toxic proteins in the absence of correct protein folding and the resultant neurodegenerative diseases. Other topics include intrinsic disorder in protein structure and function and the effects of molten globules on protein toxicity. This concise and yet thorough text also discusses using toxin structure as a model for studying structural and functional aspects of protein chemistry. 

Protein Toxins in Modeling Biochemistry, a SpringerBrief, is essential reading for advanced researchers, scientists and advanced graduate students interested in protein chemistry and related areas of biochemistry and molecular science. 


Authors and Affiliations

  • Institute of Advanced Sciences, North Dartmouth, USA

    Raj Kumar, Bal Ram Singh

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