Acute Respiratory Distress Syndrome

1. Front Matter

   Pages i-vi

   PDF

2. Acute Respiratory Distress Syndrome (ARDS): Definition, Incidence, and Outcome

   • Rémi Coudroy, Florence Boissier, Arnaud W. Thille

   Pages 1-13

3. Pathophysiology of Acute Respiratory Distress Syndrome

   • Pedro Leme Silva, Patricia R. M. Rocco

   Pages 15-27

4. Ventilation Strategies: Tidal Volume and PEEP

   • Carmen Sílvia Valente Barbas

   Pages 29-39

5. Ventilation Strategies: High-Frequency Oscillatory Ventilation

   • Spyros D. Mentzelopoulos, George Karlis, Ioannis N. Pantazopoulos, Charikleia Vrettou

   Pages 41-60

6. Ventilation Strategies: Recruitment Maneuvers

   • Lorenzo Ball, Paolo Pelosi

   Pages 61-72

7. Prone Position

   • Claude Guérin

   Pages 73-83

8. Partial or Total Extracorporeal Support

   • Nicolò Patroniti, Stefano Isgrò, Michela Bombino

   Pages 85-111

9. Hemodynamic Monitoring and Fluid Management in ARDS

   • Dusan Hanidziar, Edward A. Bittner

   Pages 113-131

10. Weaning in ARDS

    • Ross Freebairn

    Pages 133-153

11. Lung Imaging in ARDS

    • Silvia Coppola, Sara Froio, Davide Chiumello

    Pages 155-171

12. Acute Respiratory Distress Syndrome: Metabolic Support

    • Michele Umbrello, Danilo Radrizzani, Gaetano Iapichino

    Pages 173-188

13. Pharmacological Interventions: Neuromuscular Blocking Agents

    • Samuel Lehingue, Sami Hraiech, Laurent Papazian

    Pages 189-200

14. Ventilator-Induced Lung Injury

    • Michele Umbrello, Paolo Formenti

    Pages 201-223

15. Monitoring of Respiratory Mechanics

    • Andrea Aliverti

    Pages 225-243

16. Noninvasive Ventilatory Support in Acute Respiratory Distress Syndrome

    • Martin DRES, Laurent Brochard

    Pages 245-262

17. Interaction Between the Heart and Lungs

    • Fabio Guarracino, Rubia Baldassarri

    Pages 263-271

18. Stem Cells and Their Immunomodulatory Potential for the Treatment of ARDS

    • Claudia C. dos Santos

    Pages 273-290

19. Sedation

    • Giovanni Mistraletti, Paolo Formenti, Giovanni Sabbatini

    Pages 291-309

20. Acute Respiratory Distress Syndrome in Children

    • Martin C. J. Kneyber

    Pages 311-340

This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The  addressed topics are the various ventilation strategies, the impact of prone positioning, the use of partial and total extracorporeal support, the value of vasodilators, the weaning from mechanical ventilation, the pharmacological interventions, noninvasive ventilation, and the strategies using anti-inflammatory agents and stem cells. Furthermore, different related topics are also discussed, such as lung imaging, sedation, metabolic support, and hemodynamic instability. A concluding chapter specifically addresses ARDS in children. This up-to-date volume, written by  experts in the field, will be of value for all health care practitioners seeking state of the art on the management of patients with this complex syndrome.

• ARDS in children
• Extracorporeal support
• Lung imaging
• Mechanical ventilation
• Metabolic support
• Neuromuscular blocking agents
• prone position
• Stem cells
• Ventilation-induced lung injury
• Weaning

“This is an outstanding book compiled by leading world experts in the field of ARDS and thereby provides a comprehensive, accurate, and upto-date summary on the majority of aspects around ARDS. … This book is an asset for senior trainees and specialists in the field of critical care medicine but beneficial also to other health care practitioners seeking state of the art on the management of patients with ARDS.” (Adrian Regli, Britta von Ungern-Sternberg, Anesthesia & Analgesia, Vol. 126 (5), May, 2018)



“This multiauthored monograph reviews the clinical problem of acute respiratory distress syndrome (ARDS) and the focused treatment strategies and broad organ system management of patients facing this major form of hypoxemic respiratory failure seen in critical care practice. … Senior trainees and staff providers at all levels are an appropriate audience for this work … . This is an outstanding summary of recent work describing the management of one of the important syndromes in critical care medicine.” (David J. Dries, Doody's Book Reviews, September, 2017)

• Department of "Scienze della Salute", University of Milan, Director of Anaesthesia and Intensive Care Services , ASST Santi Paolo e Carlo, Milan, Italy

  Davide Chiumello

Davide Chiumello, MD, is an intensivist in the Department of Anesthesia, Intensive Care, and Pain Therapy at Fondazione IRCCS – Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy. Dr. Chiumello’s research work has focused on understanding the pathological and clinical aspects of acute respiratory distress syndrome; he has a particular interest in respiratory physiology, esophageal pressure, lung recruitment, lung imaging, ventilator-induced lung injury, the prone position, controlled and assisted mechanical ventilation, and non-invasive ventilation. Since 2009 he has been Editor-in-Chief of Minerva Anestesiologica (official journal of Società Italiana di Analgesia, Anestesia e Terapia Intensiva) and he is also a member of the editorial board of Critical Care Medicine (official journal of the Society of Critical Care Medicine). He is a reviewer for a number of international journals and since 2013 has been Editor of the Respiratory Failure section for PACT (Patient-Centred Acute Care Training) of the European Society of Intensive Care Medicine. Dr. Chiumello is the author of more than 100 scientific articles and a number of chapters in medical textbooks (H-index 24).

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