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Inflammation, Aging, and Oxidative Stress

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  • © 2016

Overview

  • Further elucidates the relationship between inflammation and oxidative stress, essential for understanding several common chronic diseases
  • Comprehensive topic coverage ranges from the mechanics of inflammation and oxidative stress to practical discussions of clinical management
  • Thorough presentation of these disorders with an emphasis on neurogenerative conditions but includes many others and is not limited to any one organ

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Table of contents (19 chapters)

  1. Age-Related Cellular Events

  2. Role of Inflammatory and Oxidative Processes in Age Related Diseases

  3. Retardation of Cellular Aging

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About this book

The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular disease, particle-induced inflammation and cardiovascular disease, Alzheimer’s disease, ovarian aging, dietary and endogenous anti-oxidants in management of Parkinson’s disease, and effects of exercise on oxidation and inflammation. The nineteen expertly authored chapters are organized into three sections in order to present a complete picture to the reader: Age Related Cellular Events, Role of Inflammatory and Oxidative Processes in Age-Related Diseases, and Retardation of Cellular Aging.

Inflammation, Oxidative Stress and Age-Related Disease draws from a variety of international perspectives and provides a comprehensive overview of the relationship between disease, cell aging, and oxidative stress, as well as potential for preventing or slowing these processes.  This installment of Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice is ideal for researchers, clinicians, and advanced graduate students in the fields of cardiology, neuroscience, biogerontolgy, and cell biology.   

Editors and Affiliations

  • Department of Medicine, Center for Occupational and Environmental Health, University of California, Irvine, USA

    Stephen C. Bondy

  • Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, USA

    Arezoo Campbell

About the editors

Arezoo Campbell received a B. A. in philosophy, a B. S. in biological sciences and a Ph.D. in environmental toxicology  from the University of California, Irvine (UCI) in Irvine, California.  She is currently an Associate Professor in the Department of Pharmaceutical Sciences at Western University of Health Sciences.  Dr. Campbell’s research emphasizes the means by which environmental exposures induce aberrant innate immune responses, which may accelerate the appearance of age-related neurodegenerative disease. Dr. Campbell also investigates the importance of inflammatory and oxidative stress in contributing to adverse changes within the brain.

Stephen Bondy received an M. A. in biochemistry from Cambridge University, in Cambridge, England and his Ph.D. in neurochemistry from Birmingham University, in Birmingham, England.  He subsequently held appointments at Columbia University, University of California Los Angeles, University of Colorado, and theNational Institutes of Environmental Health Sciences.  He is currently a Professor in the Center for Occupational and Environmental Medicine at the University of California, Irvine.  His research focuses on identifying environmental factors which may accelerate brain aging, with emphasis on understanding the mechanisms that may underlie these events.  In addition, Dr. Bondy is pursuing the development of therapeutic approaches with the potential to slow neurodegenerative processes.


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