Skip to main content
  • Book
  • © 2016

Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke

  • Discusses the roles of astrocytes, microglia, oligodendrocytes, endothelial cells, pericytes, and other immune cells
  • Explores which therapies hold promise for translation to humans
  • Only comprehensive overview of non-neuronal cells in ischemic stroke and recovery
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Series in Translational Stroke Research (SSTSR)

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xiii
  2. Microvascular Integrity in Stroke

    1. Front Matter

      Pages 1-1
    2. Structural Alterations to the Endothelial Tight Junction Complex During Stroke

      • Anuska V. Andjelkovic, Richard F. Keep
      Pages 3-23
    3. Role of Pericytes in Neurovascular Unit and Stroke

      • Turgay Dalkara, Luis Alarcon-Martinez, Muge Yemisci
      Pages 25-43
    4. Barrier Mechanisms in Neonatal Stroke

      • Zinaida S. Vexler
      Pages 81-92
    5. Angiogenesis: A Realistic Therapy for Ischemic Stroke

      • Ke-Jie Yin, Xinxin Yang
      Pages 93-108
  3. Glial Cells in Stroke

    1. Front Matter

      Pages 109-109
    2. Astrocytes as a Target for Ischemic Stroke

      • Shinghua Ding
      Pages 111-131
    3. Microglia: A Double-Sided Sword in Stroke

      • Hong Shi, Mingyue Xu, Yejie Shi, Yanqin Gao, Jun Chen, Xiaoming Hu
      Pages 133-150
    4. Crosstalk Between Cerebral Endothelium and Oligodendrocyte After Stroke

      • Akihiro Shindo, Takakuni Maki, Kanako Itoh, Nobukazu Miyamoto, Naohiro Egawa, Anna C. Liang et al.
      Pages 151-170
  4. Peripheral Immune Cells in Stroke

    1. Front Matter

      Pages 171-171
    2. The Peripheral Immune Response to Stroke

      • Josef Anrather
      Pages 173-188
    3. Regulatory T Cells in Ischemic Brain Injury

      • Arthur Liesz
      Pages 201-215
    4. B-Cells in Stroke and Preconditioning-Induced Protection Against Stroke

      • Uma Maheswari Selvaraj, Katie Poinsatte, Ann M. Stowe
      Pages 217-254
    5. Mast Cell as an Early Responder in Ischemic Brain Injury

      • Perttu J. Lindsberg, Olli S. Mattila, Daniel Strbian
      Pages 255-272
    6. Roles of Neutrophils in Stroke

      • Glen C. Jickling, Frank R. Sharp
      Pages 273-301
    7. The Function of Cytokines in Ischemic Stroke

      • Christopher C. Leonardo, Keith R. Pennypacker
      Pages 303-323
  5. White Matter Injury and Repair in Stroke

    1. Front Matter

      Pages 325-325

About this book

This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.

Editors and Affiliations

  • Department of Neurology, University of Pittsburgh, Pittsburgh, USA

    Jun Chen

  • Pittsburgh Institute of Brain Disorders and Recovery, University of Pittsburgh, Pittsburgh, USA

    John H. Zhang

  • Department of Anesthesiology, Loma Linda University School of Medicine, Loma Linda, USA

    Xiaoming Hu

Bibliographic Information

  • Book Title: Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke

  • Editors: Jun Chen, John H. Zhang, Xiaoming Hu

  • Series Title: Springer Series in Translational Stroke Research

  • DOI: https://doi.org/10.1007/978-3-319-32337-4

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-32335-0Published: 19 August 2016

  • Softcover ISBN: 978-3-319-81260-1Published: 12 June 2018

  • eBook ISBN: 978-3-319-32337-4Published: 11 August 2016

  • Series ISSN: 2363-958X

  • Series E-ISSN: 2363-9598

  • Edition Number: 1

  • Number of Pages: XIII, 408

  • Number of Illustrations: 5 b/w illustrations, 44 illustrations in colour

  • Topics: Neurosciences, Neurology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access