Overview
- Presents an overview of NF-kB-related genetic diseases
- Enables understanding of underlying pathophysiology
- Complements results from animal studies
- Includes supplementary material: sn.pub/extras
Part of the book series: SpringerBriefs in Biochemistry and Molecular Biology (BRIEFSBIOCHEM)
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Table of contents (5 chapters)
Keywords
About this book
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
Reviews
“This book provides essential concepts in the understanding of the impact of deregulated NF-kappaB activation on human health. … This book is intended for molecular biologists, human geneticists, and students interested in learning more about NF-kappaB signaling and its impact on human disease. The book is also useful for pathologists and clinicians interested in understanding more about this topic. … Several color illustrations help in the understanding of this complex subject.” (Omer Iqbal, Doody’s Book Reviews, April, 2016)
Authors and Affiliations
About the authors
Bibliographic Information
Book Title: NF-κB-Related Genetic Diseases
Authors: Gilles Courtois, Alessandra Pescatore, Jérémie Gautheron, Francesca Fusco, Matilde Valeria Ursini, Anna Senegas
Series Title: SpringerBriefs in Biochemistry and Molecular Biology
DOI: https://doi.org/10.1007/978-3-319-25850-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Author(s) 2016
Softcover ISBN: 978-3-319-25848-5Published: 08 February 2016
eBook ISBN: 978-3-319-25850-8Published: 29 December 2015
Series ISSN: 2211-9353
Series E-ISSN: 2211-9361
Edition Number: 1
Number of Pages: XII, 70
Number of Illustrations: 17 b/w illustrations
Topics: Molecular Medicine, Human Genetics, Medical Biochemistry