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  • Reference work
  • © 2017

Glucosinolates

  • Provides a timely, comprehensive reference work on glucosinolates
  • Illustrates the rich chemical and structural variety of glucosinolates
  • Introduces glucosinolates’ bioactivity and modes of action
  • Provides information on methods: from extraction and characterization, to biotechnology, applications and food processing
  • Includes supplementary material: sn.pub/extras

Part of the book series: Reference Series in Phytochemistry (RSP)

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Table of contents (15 entries)

  1. Front Matter

    Pages i-xiv
  2. Biology, Phytochemistry, Genetics, and Defense

    1. Front Matter

      Pages 1-1
    2. Glucosinolates: Novel Sources and Biological Potential

      • Ivica Blažević, Sabine Montaut, Franko Burčul, Patrick Rollin
      Pages 3-60
    3. Genetics and Breeding of Brassica Crops

      • Pablo Velasco, Víctor Manuel Rodríguez, Marta Francisco, María Elena Cartea, Pilar Soengas
      Pages 61-86
    4. Glucosinolates in Food

      • Marco Possenti, Simona Baima, Antonio Raffo, Alessandra Durazzo, Anna Maria Giusti, Fausta Natella
      Pages 87-132
    5. Accumulation of Glucosinolates in Broccoli

      • Huiying Miao, Jiansheng Wang, Congxi Cai, Jiaqi Chang, Yanting Zhao, Qiaomei Wang
      Pages 133-162
    6. Glucosinolates and Plant Defense

      • Astha Singh
      Pages 237-246
  3. Biological Activity

    1. Front Matter

      Pages 247-247
    2. Antimicrobial Activity of the Glucosinolates

      • Federica Saladino, Keliani Bordin, Fernando Bittencourt Luciano, Mónica Fernández Franzón, Jordi Mañes, Giuseppe Meca
      Pages 249-274
    3. Neuroprotective Effects of Glucosinolates

      • Cristina Angeloni, Silvana Hrelia, Marco Malaguti
      Pages 275-299
    4. Antileukemic Activity of Sulforaphane

      • Elena Catanzaro, Carmela Fimognari
      Pages 301-317
    5. Sulforaphane and Atherosclerosis

      • Pon Velayutham Anandh Babu, Chrissa Petersen, Zhenquan Jia
      Pages 319-337
  4. Analytical and Processing Methods

    1. Front Matter

      Pages 381-381
    2. Processing and Preparation of Brassica Vegetables and the Fate of Glucosinolates

      • Probo Yulianto Nugrahedi, Matthijs Dekker, Ruud Verkerk
      Pages 407-429
    3. Investigation of Glucosinolates by Mass Spectrometry

      • Giuliana Bianco, Raffaella Pascale, Filomena Lelario, Sabino A. Bufo, Tommaso R. I. Cataldi
      Pages 431-461
  5. Back Matter

    Pages 463-473

About this book

This is the first comprehensive reference compilation on the substance class of glucosinolates. This handbook introduces the reader to the sulfur-containing glucosinolates (S-glucosides), a class of secondary metabolites of almost all plants of the order Capparales, in particular in the family Brassicaceae (e.g. broccoli and other cabbages), derived from glucose and an amino acid. The book illustrates the natural variety of glucosinolate structures, mainly derived from the precursor amino acid. Chapters describe the resulting rich bioactivity of the glucosides, for example as anti-cancer agents, insecticides, nematicides, fungicides, their potential phytotoxic effects, antimicrobial activity and their possible role in neurodegenerative diseases and human health. Different methods for the extraction, characterization, quantification and processing of the glucosinolates are introduced, and potential applications are discussed. The fate of glucosinolates during food processing is also briefly addressed. This handbook is written by leading experts and structured in different sections addressing the natural occurrence of glucosinolates, their (bio-)synthesis, bioactivity, food processing of glucosinolate-containing vegetables, health and disease-related aspects, biotechnology, and methods applied in glucosinolate-research. It is thus a rich reference source for every reader working in the field, from chemists and biotechnologists, to life scientists, pharmacists and medical scientists.

Editors and Affiliations

  • Faculty of Pharmaceutical Sciences, University of Bordeaux, Bordeaux, France

    Jean-Michel Mérillon

  • Botany Department, M.L. Sukhadia University, Udaipur, India

    Kishan Gopal Ramawat

About the editors

Prof. Dr. Kishan G. Ramawat is Former Professor & Head of the Botany Department, M.L. Sukhadia University, Udaipur, India, and can look back on longstanding research experience. He received his Ph.D. in Plant Biotechnology in 1978 from the University of Jodhpur, India and afterwards joined the university as a faculty member. In 1991 he moved to the M.L.Sukhadia University in Udaipur as Associate Professor and became Professor in 2001. He served as the Head of the Department of Botany (2001-2004, 2010-2012), was in charge of the Department of Biotechnology (2003-2004), was a member of the task force on medicinal and aromatic plants of the Department of Biotechnology, Government of India, New Delhi (2002-2005) and coordinated UGC-DRS and DST-FIST programmes (2002-2012). Prof. Ramawat had done his postdoctoral studies at the University of Tours, France from 1983-85, and later returned to Tours as visiting professor (1991). He also visited the University of Bordeaux 2, France several times as visiting professor (1995, 1999, 2003, 2006, 2010), and in 2005 Poland in an academic exchange programme (2005). Through these visits in France, Prof. Ramawat and Prof. Mérillon established a strong connection, which has resulted in productive collaborations and several book and reference work publications. Prof. Ramawat has published more than 170 well cited peer reviewed papers and articles, and edited several books and reference works on topics such as the biotechnology of medicinal plants, secondary metabolites, bioactive molecules, herbal drugs, and many other topics. His research was funded by several funding agencies. In his research group, Prof. Ramawat has supervised doctoral thesis of 25 students. He is an active member of several academic bodies, associations and editorial boards of journals.

Professeur Dr. Jean-Michel Merillon is the « Directeur de l’EA 3675 (Groupe d’Etude des Substances Vegetales à Activité Biologique + Polyphenols Biotech) », at the Faculte de Pharmacie, Universite de Bordeaux, Institut des Sciences de la Vigne et du Vin, in Villenave d’Ornon, France. He received his M.Pharma. (1979) and Ph.D. (1984) from the University of Tours in France. He joined the University of Tours as assistant professor in 1981, became associate professor in 1987. In 1993 he moved to the faculty of Pharmacy, University of Bordeaux, France, accepting a position as full professor. He is currently leading the “study group on biologically active plant substances” at the Institute of Vine and Wine Sciences, which comprises 25 scientists and research students. The group has been working on phenolic compounds from vine and wine for many years, mainly complex stilbenes and their involvement in health. Prof. Mérillon has supervised the doctoral theses of 19 students. He is involved in developing teaching on plant biology, natural bioactive compounds and biotechnology.  Prof. Mérillon has published more than 145 research papers ininternationally recognized journals, resulting in an H index of 35 (documents published between 1996 and 2015). He has co-edited books and reference works on secondary metabolites and biotechnology. Throughout his career, Prof. Mérillon has traveled widely as a senior professor. Scientists from several countries have been and are working in his laboratory, and his research is supported by funding from the Aquitaine Regional Government, the Ministry of Higher Education and Research, and various private companies. In 2004, he founded the technology transfer unit “Polyphenols Biotech”, providing support for R&D programs for SMEs and major groups from the cosmetic, pharmaceutical, agricultural and health-nutrition sectors.

Bibliographic Information

Buy it now

Buying options

Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access