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Translational Approaches to Autism Spectrum Disorder

  • Book
  • © 2015

Overview

Editors:
  1. Maria de los Angeles Robinson-Agramonte

    1. Neuroimmunology Department, International Center for Neurological Restoration, Havana, Cuba

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  • Offers a comprehensive view of translational research on autism spectrum disorder

  • Provides guidance to relevant research methods for work with animal models

  • Combines experimental and clinical perspectives to address potential therapy options

  • Includes supplementary material: sn.pub/extras

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Autism: What Is It?

    • Roberta Maresca, Laura de Magistris
    Pages 1-11

  3. Epidemiology of Autism Spectrum Disorders

    • Alison Presmanes Hill, Katharine Zuckerman, Eric Fombonne
    Pages 13-38

  4. The Genetic Basis of Autism Spectrum Disorder

    • Jaqueline Bohrer Schuch, Luiza Monteavaro Mariath, Tatiana Roman, Lavinia Schuler-Faccini
    Pages 39-63

  5. Autism Spectrum Disorder. A Clinical Neurophysiology Approach I

    • Lilia María Morales Chacón, Margarita Minou Báez Martin
    Pages 65-83

  6. Autism Spectrum Disorder. A Clinical Neurophysiology Approach II

    • Margarita Minou Baez Martin, Lilia María Morales Chacón, Ivette Cabrera Abreu
    Pages 85-94

  7. Neuroimages in Autism

    • Rafael Rodríguez-Rojas, Calixto Machado, Karla Batista, Maylen Carballo, Gerry Leisman
    Pages 95-117

  8. Autism, Development and Neural Plasticity

    • Maria de los Angeles Robinson-Agramonte, Maria Elena Gonzàlez Fraguela, Jorge Bergado-Rosado
    Pages 119-135

  9. Neuroinflammation in Animal Models of Autism

    • Nadia Kazlauskas, Maria de los Angeles Robinson-Agramonte, Amaicha Mara Depino
    Pages 137-153

  10. Understanding on Neuroimmunology in Autism Spectrum Disorder

    • Amaicha Mara Depino, Maria de los Angeles Robinson-Agramonte
    Pages 155-180

  11. Antibody Mediating Autoimmune Reaction in Autism Spectrum Disorder

    • Elena Noris-García, Mercedes Adalys Rodríguez-Ravelo, Yamila Adams Villalón, Gustavo Sierra, Maria de los Angeles Robinson-Agramonte
    Pages 181-193

  12. Current Therapies

    • Dario Siniscalco, Nicola Antonucci
    Pages 195-207

  13. Back Matter

    Pages 209-218
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Keywords

About this book

This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any, proven therapies for the majority of the disorders. Among the topic addressed are neural plasticity, neuroimmunology, neuroinflammation, neuroimaging, and appropriate animal and genetic models.

Reviews

“This book presents a constellation of research and clinical perspectives on autism spectrum disorder (ASD) … . This is a great resource and reference for students, researchers, and even clinicians who are particularly interested in ASD. Each chapter discusses various areas and aspects of ASD, which are nicely explained in detail while also providing broad conceptualization.” (Soo Lee, Doody’s Book Reviews, December, 2015)

Editors and Affiliations

  • Neuroimmunology Department, International Center for Neurological Restoration, Havana, Cuba

    Maria de los Angeles Robinson-Agramonte

About the editor

Maria de los Angeles Robinson-Agramonte is the Head of Project Biomolecular Markers and Neurointervention in Autism Spectrum Disorders in the division of Science and Technology, CIREN, International Center for Neurological Restoration. She graduated from the Medical University of Santiago de Cuba with an MD, and went on to receive her Ph. D. in Immunology from the Medical School at Havana University. Dr. Robinson-Agramonte has since worked on basic and clinical research projects on Neurodegenerative diseases like Alzheimer’s disease, Demyelinating diseases, and Neurodevelopment diseases with a focus on ASD. She has published more than 35 publications and five book chapters. She has won various National Annual Prizes, including the Cuban Science Academy award and the Cuban Society of Immunology’s Clinical Research Award.

Bibliographic Information

  • Book Title: Translational Approaches to Autism Spectrum Disorder

  • Editors: Maria de los Angeles Robinson-Agramonte

  • DOI: https://doi.org/10.1007/978-3-319-16321-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-16320-8Published: 29 June 2015

  • Softcover ISBN: 978-3-319-38657-7Published: 17 October 2016

  • eBook ISBN: 978-3-319-16321-5Published: 10 June 2015

  • Edition Number: 1

  • Number of Pages: XIV, 218

  • Number of Illustrations: 8 b/w illustrations, 11 illustrations in colour

  • Topics: Neurosciences, Neurology

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