Skip to main content
SpringerLink
Log in

Toxicity and Autophagy in Neurodegenerative Disorders

  • Book
  • © 2015

Overview

Editors:
  1. José M. Fuentes

    1. Bioquímica y Biología Molecular y Gen., Facultad de Enfermería y T.O., Cáceres, Spain

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Evaluates the interplay between autophagy and toxicity in neurodegenerative disease
  • Contains contributions from an international group of experts
  • Addresses the major diseases: Alzheimer's, Parkinson's, Huntington's
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Neurotoxicity (Current Topics Neurotoxicity, volume 9)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (13 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Regulation of Autophagy in Health and Disease

    • Amal Arachiche, Devrim Gozuacik
    Pages 1-24

  3. Role of Chaperone-Mediated Autophagy in Ageing and Neurodegeneration

    • J.V. Ferreira, P. Pereira, H. Girao
    Pages 25-40

  4. Interaction Between Mitochondria and Autophagy

    • Matthew E. Gegg
    Pages 41-61

  5. Dual Role of Autophagy in Neurodegenerative Diseases: The Case of Amyotrophic Lateral Sclerosis

    • Leslie Bargsted, René L. Vidal, Claudio Hetz, Soledad Matus
    Pages 63-78

  6. Autophagy Pathways in Huntington’s Disease

    • María Ángeles Mena, Juan Perucho, Marian Fernandez-Estevez, Justo García de Yébenes
    Pages 79-89

  7. Control of Autophagy in Parkinson’s Disease

    • Rosa A. González-Polo, Rubén Gómez-Sánchez, Elisa Pizarro-Estrella, Sokhna M. S. Yakhine-Diop, Mario Rodríguez-Arribas, José M. Fuentes
    Pages 91-122

  8. Autophagy in Alzheimer’s disease: A Cleaning Service Out-of-order?

    • Sónia C. Correia, Paula I. Moreira, George Perry
    Pages 123-142

  9. Autophagy as a Neuroprotective Mechanism Against 3-Nitropropionic Acid-Induced Cell Death

    • Maria F. Galindo, Sara Saez-Atienzar, Luis Bonet-Ponce, Joaquín Jordan
    Pages 143-157

  10. Paraquat: Molecular Mechanisms of Neurotoxicity and its Relation with Autophagy

    • Maria Teresa Baltazar, Ricardo Jorge Dinis-Oliveira, Maria de Lourdes Bastos, Félix Carvalho
    Pages 159-170

  11. Agrochemicals-Induced Dopaminergic Neurotoxicity: Role of Mitochondria-Mediated Oxidative Stress and Protein Clearance Mechanisms

    • Neeraj Singh, Vivek Lawana, Niranjana Krishnan, Sri Harsha Kanuri, Huajun Jin, Vellareddy Anantharam et al.
    Pages 171-204

  12. Molecular and Neurochemical Mechanisms Dopamine Oxidation To O-Quinones in Parkinson’s Disease Pathogenesis

    • Patricia Muñoz, Catalina Melendez, Irmgard Paris, Juan Segura-Aguilar
    Pages 205-223

  13. Exploring the Role of Autophagy in the Pathogenesis of Rotenone-induced Toxicity

    • Gessica Sala, Giovanni Stefanoni, Daniele Marinig, Carlo Ferrarese
    Pages 225-245

  14. Autophagic Pathology and Calcium Deregulation in Neurodegeneration

    • Patricia Gómez-Suaga, Sabine Hilfiker
    Pages 247-266

  15. Back Matter

    Pages 267-268
    Download chapter PDF
Back to top

Keywords

About this book

Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

Reviews

“This is a very good book for students and researchers involved with biochemical and cellular pathways of immune responses after cell toxicity due to neurodegenerative processes. I highly recommend the book to neurologists, physiologists, and biochemists.” (Joseph J.  Grenier, Amazon.com, January, 2016)

Editors and Affiliations

  • Bioquímica y Biología Molecular y Gen., Facultad de Enfermería y T.O., Cáceres, Spain

    José M. Fuentes

Bibliographic Information

  • Book Title: Toxicity and Autophagy in Neurodegenerative Disorders

  • Editors: José M. Fuentes

  • Series Title: Current Topics in Neurotoxicity

  • DOI: https://doi.org/10.1007/978-3-319-13939-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-13938-8Published: 19 May 2015

  • Softcover ISBN: 978-3-319-38212-8Published: 17 October 2016

  • eBook ISBN: 978-3-319-13939-5Published: 04 May 2015

  • Series ISSN: 2363-9563

  • Series E-ISSN: 2363-9571

  • Edition Number: 1

  • Number of Pages: XV, 268

  • Number of Illustrations: 7 b/w illustrations, 27 illustrations in colour

  • Topics: Neurochemistry

Publish with us

Policies and ethics

Back to top

Search

Navigation