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  • © 2021

Advances in Glycobiotechnology

  • Outlines recombinant glycoprotein expression in different host systems
  • Discusses the role of glycosylation on protein function and vaccine development
  • Updates on cutting edge glycoanalytical technologies
  • Sets out future directions in glycobiotechnology and glycoanalysis

Part of the book series: Advances in Biochemical Engineering/Biotechnology (ABE, volume 175)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-viii
  2. Animal Cell Expression Systems

    • M. Butler, U. Reichl
    Pages 1-36
  3. Glycoengineering of Mammalian Expression Systems on a Cellular Level

    • Kelley M. Heffner, Qiong Wang, Deniz Baycin Hizal, Özge Can, Michael J. Betenbaugh
    Pages 37-69
  4. Glycobiotechnology of the Insect Cell-Baculovirus Expression System Technology

    • Laura A. Palomares, Indresh K. Srivastava, Octavio T. Ramírez, Manon M. J. Cox
    Pages 71-92
  5. Engineering of Yeast Glycoprotein Expression

    • Charlot De Wachter, Linde Van Landuyt, Nico Callewaert
    Pages 93-135
  6. Glyco-Engineering of Plant-Based Expression Systems

    • Rainer Fischer, Tanja Holland, Markus Sack, Stefan Schillberg, Eva Stoger, Richard M. Twyman et al.
    Pages 137-166
  7. Bacterial Glycoengineering as a Biosynthetic Route to Customized Glycomolecules

    • Laura E. Yates, Dominic C. Mills, Matthew P. DeLisa
    Pages 167-200
  8. Advances in the Chemical Synthesis of Carbohydrates and Glycoconjugates

    • Ankita Malik, Peter H. Seeberger, Daniel Varón Silva
    Pages 201-230
  9. Enzymatic Synthesis of Glycans and Glycoconjugates

    • Thomas Rexer, Dominic Laaf, Johannes Gottschalk, Hannes Frohnmeyer, Erdmann Rapp, Lothar Elling
    Pages 231-280
  10. Impact of Protein Glycosylation on the Design of Viral Vaccines

    • Kathleen Schön, Bernd Lepenies, Guillaume Goyette-Desjardins
    Pages 319-354
  11. Interplay of Carbohydrate and Carrier in Antibacterial Glycoconjugate Vaccines

    • Tyler D. Moeller, Kevin B. Weyant, Matthew P. DeLisa
    Pages 355-378
  12. State-of-the-Art Glycomics Technologies in Glycobiotechnology

    • Alexander Pralow, Samanta Cajic, Kathirvel Alagesan, Daniel Kolarich, Erdmann Rapp
    Pages 379-411
  13. Glycoproteomics Technologies in Glycobiotechnology

    • Kathirvel Alagesan, Marcus Hoffmann, Erdmann Rapp, Daniel Kolarich
    Pages 413-434
  14. Glycan Array Technology

    • Juana Elizabeth Reyes Martinez, Baptiste Thomas, Sabine Lahja Flitsch
    Pages 435-456
  15. Erratum to: Animal Cell Expression Systems

    • M. Butler, U. Reichl
    Pages 457-457
  16. Correction to: Animal Cell Expression Systems

    • M. Butler, U. Reichl
    Pages 459-461
  17. Correction to: Enzymatic Synthesis of Glycans and Glycoconjugates

    • Thomas Rexer, Dominic Laaf, Johannes Gottschalk, Hannes Frohnmeyer, Erdmann Rapp, Lothar Elling
    Pages 463-463

About this book

This book reviews the latest trends in glycobiotechnology, it offers an authoritative discussion about future directions of glycoengineering, and it provides a comprehensive overview about the current and emerging approaches to identify, quantify and characterize glycosylated proteins.

Divided into 14 chapters, the book outlines recombinant glycoprotein expression in mammalian cells, insect cells, yeast, and bacterial systems. It covers the chemical and enzymatic syntheses of glycans and glyconjugates, and addresses the impact of glycosylation on protein function for the development of biologicals including vaccines. In the final chapters of the book, readers will discover more about the state-of-the-art in glycomics, glycoproteomics and glycan array technologies.



Editors and Affiliations

  • Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany

    Erdmann Rapp, Udo Reichl

  • glyXera GmbH, Magdeburg, Germany

    Erdmann Rapp

  • Otto-von-Guericke University Magdeburg, Magdeburg, Germany

    Udo Reichl

About the editors

Dr. Erdmann Rapp is heading the Bio/Process Analytics team of the Bioprocess Engineering Department at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg and founder, CEO & CSO of glyXera, providing tailored cutting-edge glycoanalytical products and services. He is an experienced researcher, inventor, mentor and university lecturer. He and his team are working on the development and implementation of innovative bio/process analytics - in particular, on sophisticated tools for proteomics, glycoproteomics and glycomics - for a deeper understanding of biological and biotechnological processes. Dr. Rapp’s successful research is documented by more than 120 peer-reviewed papers and book chapters, and 8 patents.

Professor Udo Reichl is a Scientific Member of the Max Planck Society, Director of the Bioprocess Engineering Department of the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg and Chair of Bioprocess Engineering at the Otto-von-Guericke University Magdeburg. He has profound expertise in the development and optimization of cell culture-based viral vaccine production. His group developed sophisticated analytical tools to monitor process dynamics, metabolism of cell lines, infection dynamics and the glycosylation of viral and recombinant proteins. His list of publications comprises more than 250 peer-reviewed papers and book chapters, and he has filed various patents.



Bibliographic Information

Buy it now

Buying options

eBook USD 299.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 379.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access