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Inflammation and Epilepsy: New Vistas

  • Book
  • © 2021

Overview

  • First comprehensive volume discussing epilepsy as an inflammatory disease
  • Projected towards the future, not a review of the past
  • Of interest to both neurologists and neuroscientists

Part of the book series: Progress in Inflammation Research (PIR, volume 88)

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Table of contents (11 chapters)

Keywords

About this book

This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.


Editors and Affiliations

  • Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, USA

    Damir Janigro

  • INSERM, Strasbourg, France

    Astrid Nehlig

  • Cerebrovascular and Glia Research, Department of Neuroscience, Institute of Functional Genomics (UMR 5203 CNRS – U 1191 INSERM, University of Montpellier), Montpellier, France

    Nicola Marchi

About the editors

Damir Janigro

Department of Physiology and Biophysics

Case Western Reserve University

Cleveland

Ohio

USA

 

Astrid Nehlig

INSERM

Strasbourg

France

    

Nicola Marchi

Cerebrovascular and Glia Research, Department of Neuroscience

Institute of Functional Genomics

Montpellier,

France

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