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Progress in the Chemistry of Organic Natural Products 115

  • Book
  • © 2021

Overview

  • Written by recognized authorities in the field
  • Provides comprehensive and up-to-date reviews on the topic
  • Part of a well-known series

Part of the book series: Progress in the Chemistry of Organic Natural Products (POGRCHEM, volume 115)

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Table of contents (5 chapters)

Keywords

About this book

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

Editors and Affiliations

  • College of Pharmacy, Ohio State University, Columbus, USA

    A. Douglas Kinghorn

  • Institute of Organic Chemistry, Johannes Kepler University, Linz, Austria

    Heinz Falk

  • School of Pharmacy, University of East Anglia, NORWICH, UK

    Simon Gibbons

  • Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan

    Yoshinori Asakawa

  • School of Pharmaceutical Sciences, South Central University for Nationaliti, Wuhan, China

    Ji-Kai Liu

  • Department of Pharmacognosy, University of Vienna, Wien, Austria

    Verena M. Dirsch

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