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Clinical, Biological and Molecular Aspects of COVID-19

  • Book
  • © 2021

Overview

Editors:
  1. Paul C. Guest

    1. University of Campinas, São Paulo, Brazil

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  • Addresses the current global pandemic and increases understanding of current challenges
  • Discusses effects of COVID-19 on individuals with co-morbid diseases and gives insights into potential treatments
  • Provides results of cross-sectional survey studies from different COVID-19-impacted communities
  • Gives insights which may help us to address future pandemics more effectively

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1321)

Part of the book sub series: Proteomics, Metabolomics, Interactomics and Systems Biology (PMISB)

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Table of contents (30 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Reviews

    1. Front Matter

      Pages 1-1
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    2. SARS-CoV-2 (COVID-19): Beginning to Understand a New Virus

      • Giau Van Vo, Eva Bagyinszky, Yoon Soo Park, John Hulme, Seong Soo A. An
      Pages 3-19

    3. Neurological Complications of the COVID-19 Pandemic: What Have We Got So Far?

      • Isabelle Pastor Bandeira, Marco Antônio Machado Schlindwein, Leticia Caroline Breis, Jean Pierre Schatzmann Peron, Marcus Vinícius Magno Gonçalves
      Pages 21-31

    4. Endothelial Dysfunction as a Primary Consequence of SARS-CoV-2 Infection

      • Genevieve Mezoh, Nigel J. Crowther
      Pages 33-43

    5. A Review Study on the Neonatal Outcomes of Pregnant Women with COVID-19

      • Somayeh Makvandi, Mitra Mahdavian, Goli Kazemi-Nia, Amir Vahedian-Azimi, Leila Karimi, Amirhossein Sahebkar
      Pages 45-51

    6. Relationship Between COVID-19 and Angiotensin-Converting Enzyme 2: A Scoping Review

      • Asma Shojaee, Amir Vahedian-Azimi, Fakhrudin Faizi, Farshid Rahimi-Bashar, Alireza Shahriary, Hadi Esmaeili Gouvarchin Galeh et al.
      Pages 53-68

    7. Experience in Nutrition Management of Diabetes-Affected COVID-19 Patients

      • Behnaz Abiri, Paul C. Guest, Mohammadreza Vafa
      Pages 69-80

    8. Emerging Technologies for the Treatment of COVID-19

      • Hossein Aghamollaei, Rahim Sarvestani, Hamid Bakherad, Hamed Zare, Paul C. Guest, Reza Ranjbar et al.
      Pages 81-96

    9. Obesity and Risk of COVID-19 Infection and Severity: Available Evidence and Mechanisms

      • Behnaz Abiri, Paul C. Guest, Mohammadreza Vafa
      Pages 97-107

    10. COVID-19 Is an Endothelial Disease: Implications of Nitric Oxide

      • Jason Kidde, Armita Mahdavi Gorabi, Tannaz Jamialahmadi, Amirhossein Sahebkar
      Pages 109-113

    11. The Immune Response and Effectiveness of COVID-19 Therapies

      • Fataneh Tavasolian, Gholam Reza Hatam, Sayed Hussain Mosawi, Mahdiyar Iravani Saadi, Elham Abdollahi, Tannaz Jamialahmadi et al.
      Pages 115-126

    12. The Novel Coronavirus and Inflammation

      • J. A. George, E. S. Mayne
      Pages 127-138

    13. Does SARS-CoV-2 Threaten Male Fertility?

      • Amir Vahedian-Azimi, Leila Karimi, Somayeh Makvandi, Tannaz Jamialahmadi, Amirhossein Sahebkar
      Pages 139-146

    14. COVID-19 and Vulnerable Populations in Sub-Saharan Africa

      • J. A. George, M. R. Maphayi, T. Pillay
      Pages 147-162

    15. Overview of the Haematological Effects of COVID-19 Infection

      • T. M. Wiggill, E. S. Mayne, J. L. Vaughan, S. Louw
      Pages 163-172

    16. The Novel Coronavirus and Haemostatic Abnormalities: Pathophysiology, Clinical Manifestations, and Treatment Recommendations

      • S. Louw, B. F. Jacobson, E. S. Mayne, T. M. Wiggill
      Pages 173-180

  3. Clinical Studies

    1. Front Matter

      Pages 181-181
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    2. COVID-19-Related Laboratory Analyte Changes and the Relationship Between SARS-CoV-2 and HIV, TB, and HbA1c in South Africa

      • R. Hesse, D. J. van der Westhuizen, J. A. George
      Pages 183-197

    3. The Primary Outcomes and Epidemiological and Clinical Features of Coronavirus Disease 2019 (COVID-19) in Iran

      • Amir Vahedian-Azimi, Sara Ashtari, Gholamhosein Alishiri, Alireza Shahriary, Mohsen Saberi, Farshid Rahimi-Bashar et al.
      Pages 199-210
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Keywords

About this book

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are profound, and has required extreme social distancing measures across the globe in order to prevent overwhelming the healthcare services and hospitals. COVID-19 appears to have the greatest effects on elderly individuals and those who have co-morbid diseases, such as heart disease, asthma, and diabetes. As the peak begins to slow in many countries, the death rates remain high amidst justified fears of a second wave. A rapid worldwide mobilization has begun to identify effective treatments and develop vaccines.

This new volume will increase readers’ understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns. Leading experts will discuss the effects of the virus in cases of co-morbidities, new treatment approaches, mental health aspects of the pandemic, and convey the results of survey studies. The book will be an excellent resource for researchers studying virology, metabolic diseases, respiratory disorders, and clinical scientists, physicians, drug companies, and healthcare services and workers.

Editors and Affiliations

  • University of Campinas, São Paulo, Brazil

    Paul C. Guest

About the editor

Dr. Paul C. Guest, Ph.D, is a scientific researcher/writer with 37 years of experience in the fields of metabolic and neurological disorders. This includes experience in both academia and the pharmaceutical industry with the majority of time spent at the University of Cambridge and Merck Sharp & Dohme in the United Kingdom. He has also been affiliated with the University of Campinas in Sao Paulo Brazil since 2015, still focused on advancing the field of biomarkers for neurological disorders such as schizophrenia and Alzheimer’s disease, and more recently in the area of anti-aging research.

Bibliographic Information

  • Book Title: Clinical, Biological and Molecular Aspects of COVID-19

  • Editors: Paul C. Guest

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-59261-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-59260-8Published: 04 March 2021

  • eBook ISBN: 978-3-030-59261-5Published: 03 March 2021

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVII, 353

  • Number of Illustrations: 16 b/w illustrations, 37 illustrations in colour

  • Topics: Virology, Physiology, Chemistry/Food Science, general

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