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Tumor Microenvironments in Organs

From the Brain to the Skin – Part B

  • Provides a comprehensive overview of the state-of-the-art research on the tumor microenvironment in many organs, including brain, neck, tongue, larynges, esophagus, carotid body, breast, prostate, ovary, endometrium, liver, pancreas, bladder, penis, seminal vesicle, retina, and pituitary, pineal and sweat glands, and more
  • Illustrates how cancer cells in distinct tissues are affected by different components of the tumor microenvironment
  • Identifies specific components in the tumor microenvironment for each tissue type that may become specific targets for cancer treatment

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1296)

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xvii
  2. Targeting Glioblastoma Tumor Microenvironment

    • Megan Butler, Sahdeo Prasad, Sanjay K. Srivastava
    Pages 1-9
  3. Recent Advances in Head and Neck Tumor Microenvironment–Based Therapy

    • Muzafar A. Macha, Nissar A. Wani, Rais A. Ganai, Ajaz A. Bhat, Abid Hamid, Sheema Hashem et al.
    Pages 11-31
  4. Meningioma Tumor Microenvironment

    • Sajad Sahab-Negah, Ali Gorji
    Pages 33-48
  5. The Microenvironment of Tongue Cancer

    • Want Tao, Zeng Li-Juan, Li Kan, Li Jing-Yuan, Liu Xiang-Qi, Liang Yu-Jie
    Pages 49-78
  6. Laryngeal Tumor Microenvironment

    • Georgia Karpathiou, Jean Marc Dumollard, Michel Peoc’h
    Pages 79-101
  7. Esophageal Tumor Microenvironment

    • Henrik Nienhüser, Naita Wirsik, Thomas Schmidt
    Pages 103-116
  8. The Pituitary Tumors and Their Tumor-Specific Microenvironment

    • M. M. Kameda-Smith, J. -Q. Lu
    Pages 117-135
  9. Pineal Gland Tumor Microenvironment

    • Joham Choque-Velasquez, Szymon Baluszek, Roberto Colasanti, Sajjad Muhammad, Juha Hernesniemi
    Pages 137-150
  10. Carotid Body Tumor Microenvironment

    • Jean-Paul Bryant, Shelly Wang, Toba Niazi
    Pages 151-162
  11. The Mammary Tumor Microenvironment

    • Colleen S. Curran, Suzanne M. Ponik
    Pages 163-181
  12. Integrated Therapeutic Targeting of the Prostate Tumor Microenvironment

    • Lydia Livas, Sumati Hasani, Natasha Kyprianou
    Pages 183-198
  13. The Many Microenvironments of Ovarian Cancer

    • Hannah M. Micek, Mike R. Visetsouk, Andrew J. Fleszar, Pamela K. Kreeger
    Pages 199-213
  14. Endometrial Tumour Microenvironment

    • Carlos Casas-Arozamena, Miguel Abal
    Pages 215-225
  15. Liver Tumor Microenvironment

    • Diamantis I. Tsilimigras, Ioannis Ntanasis-Stathopoulos, Dimitrios Moris, Timothy M. Pawlik
    Pages 227-241
  16. Pancreatic Tumor Microenvironment

    • Kai Wang, Hong He
    Pages 243-257
  17. Sweat Gland Tumor Microenvironment

    • Adeodatus Yuda Handaya, Sumadi Lukman Anwar, Aditya Rifqi Fauzi, Victor Agastya Pramudya Werdana
    Pages 259-274
  18. The Tumor Microenvironment of Bladder Cancer

    • Ken Hatogai, Randy F. Sweis
    Pages 275-290
  19. Tumor Microenvironment in Penile Cancer

    • Matthias Walter
    Pages 291-307
  20. Seminal Vesicle Tumor Microenvironment

    • Alessia Cimadamore, Rodolfo Montironi, Sergio Serni, Riccardo Campi
    Pages 309-318

About this book

Revealing essential roles of the tumor microenvironment components in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in several organs, including brain, neck, tongue, larynges, esophagus, carotid body, breast, prostate, ovary, endometrium, liver, pancreas, bladder, penis, seminal vesicle, retina, and pituitary, pineal and sweat glands, and more.

Taken alongside its companion volumes, Tumor Microenvironments in Organs: From the Brain to the Skin – Part B updates us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Editors and Affiliations

  • Department of Radiology, Columbia University Medical Center, New York, NY, USA, Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Brazil

    Alexander Birbrair

About the editor

Alexander Birbrair received his bachelor’s biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global YoungAcademy (GYA). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals, including Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.

Bibliographic Information

  • Book Title: Tumor Microenvironments in Organs

  • Book Subtitle: From the Brain to the Skin – Part B

  • Editors: Alexander Birbrair

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-59038-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-59037-6Published: 30 June 2021

  • Softcover ISBN: 978-3-030-59040-6Published: 01 July 2022

  • eBook ISBN: 978-3-030-59038-3Published: 29 June 2021

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVII, 376

  • Topics: Cancer Research, Cell Biology, Internal Medicine

Buy it now

Buying options

eBook USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access