Editors:
- Provides an understanding of the mechanisms by which multiple factors and therapeutic agents affect bones
- Gives an overview of the genetics of bone disorders and discusses the pathophysiology of osteoporosis
- Maximizes insights in current and potential osteoporosis therapies and treatments
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 262)
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Table of contents (20 chapters)
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Front Matter
About this book
This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.
Editors and Affiliations
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Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, USA
Paula H. Stern
Bibliographic Information
Book Title: Bone Regulators and Osteoporosis Therapy
Editors: Paula H. Stern
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-030-57378-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-57377-5Published: 29 November 2020
Softcover ISBN: 978-3-030-57380-5Published: 30 November 2021
eBook ISBN: 978-3-030-57378-2Published: 28 November 2020
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: X, 518
Number of Illustrations: 1 b/w illustrations
Topics: Pharmacology/Toxicology, Cell Physiology, Cytokines and Growth Factors, Metabolic Diseases, Receptors, Endocrinology