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Substance Use Disorders

From Etiology to Treatment

  • Book
  • © 2020

Overview

Editors:
  1. Michael A. Nader

    1. Wake Forest School of Medicine, Winston-Salem, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Yasmin L. Hurd

    1. Addiction Institute of Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Focuses on each substance used and abused from epidemiology, molecular biology, animal models and human subjects/clinical research reinforcing basic principles of pharmacology throughout
  • Broadens understanding of the commonalities and differences associated with each drug of abuse
  • Provides the reader with state-of-the-art, cutting edge research methods

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 258)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Methods for Population Research on Substance Use and Consequences

    • Mark Wolfson, Kimberly G. Wagoner, Eunyoung Y. Song, Melinda Pankratz, Sunday Azagba
    Pages 1-29

  3. Translational Molecular Approaches in Substance Abuse Research

    • Sasha L. Fulton, Ian Maze
    Pages 31-60

  4. Small Molecule Neuropeptide S and Melanocortin 4 Receptor Ligands as Potential Treatments for Substance Use Disorders

    • Bruce Blough, Ojas Namjoshi
    Pages 61-87

  5. Emerging Insights into Mu Opioid Pharmacology

    • Gavril W. Pasternak, Steven R. Childers, Ying-Xian Pan
    Pages 89-125

  6. Behavioral Pharmacology of Drugs Acting at Mu Opioid Receptors

    • Lisa R. Gerak, David R. Maguire, Charles P. France
    Pages 127-145

  7. The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research

    • Matthew L. Banks
    Pages 147-165

  8. Clinical Trials for Opioid Use Disorder

    • Esther Blessing, Sanya Virani, John Rotrosen
    Pages 167-202

  9. Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms

    • Bianca Jupp, Jolyon A. Jones, Jeffrey W. Dalley
    Pages 203-230

  10. Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder

    • Alberto J. López, Cody A. Siciliano, Erin S. Calipari
    Pages 231-263

  11. Molecular Mechanisms of Amphetamines

    • Maarten E. A. Reith, Margaret E. Gnegy
    Pages 265-297

  12. Clinical Trials for Stimulant Use Disorders: Addressing Heterogeneities That May Undermine Treatment Outcomes

    • Paul S. Regier, Kyle M. Kampman, Anna Rose Childress
    Pages 299-322

  13. Molecular Mechanism and Cannabinoid Pharmacology

    • Lesley D. Schurman, Dai Lu, Debra A. Kendall, Allyn C. Howlett, Aron H. Lichtman
    Pages 323-353

  14. Pharmacotherapies for Cannabis Use Disorders: Clinical Challenges and Promising Therapeutic Agents

    • Suzanne Nielsen, Pamela Sabioni, Linda Gowing, Bernard Le Foll
    Pages 355-372

  15. Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence

    • Christie D. Fowler, Jill R. Turner, M. Imad Damaj
    Pages 373-393

  16. Randomized Clinical Trials Investigating Innovative Interventions for Smoking Cessation in the Last Decade

    • Marie N. S. Gendy, Christine Ibrahim, Matthew E. Sloan, Bernard Le Foll
    Pages 395-420

  17. Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies

    • Brian A. McCool, Molly M. McGinnis
    Pages 421-442

  18. Medication Development for Alcohol Use Disorder: A Focus on Clinical Studies

    • Lorenzo Leggio, Daniel E. Falk, Megan L. Ryan, Joanne Fertig, Raye Z. Litten
    Pages 443-462

  19. Newly Emerging Drugs of Abuse

    • Kenichi Tamama, Michael J. Lynch
    Pages 463-502
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Keywords

About this book

The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use disorders. The first section is dedicated to methodology including population-based surveys, basic neuroanatomy, chemistry, molecular biology, behavioral models and brain imaging. The second section utilizes this methodology in research related to opioids, cocaine, marijuana, alcohol and nicotine. The book is aimed at both professionals (academics, clinicians, practitioners) and students or trainees.

Editors and Affiliations

  • Wake Forest School of Medicine, Winston-Salem, USA

    Michael A. Nader

  • Addiction Institute of Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, USA

    Yasmin L. Hurd

Bibliographic Information

  • Book Title: Substance Use Disorders

  • Book Subtitle: From Etiology to Treatment

  • Editors: Michael A. Nader, Yasmin L. Hurd

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-030-33679-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-33678-3Published: 20 May 2020

  • Softcover ISBN: 978-3-030-33681-3Published: 20 May 2021

  • eBook ISBN: 978-3-030-33679-0Published: 19 May 2020

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: X, 502

  • Number of Illustrations: 1 b/w illustrations

  • Topics: Pharmacology/Toxicology

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