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  • © 2019

Essential Pharmaceutics

  • Presents a modern teaching style using a flipped classroom
  • Integrated updated case studies
  • Based upon modern pharmaceutic products

Part of the book series: AAPS Introductions in the Pharmaceutical Sciences (AAPSINSTR)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
  2. Essential Pharmaceutics in the Flipped Classroom

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 1-9
  3. Preformulation in Drug Product Design

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 11-33
  4. Capsule and Tablet Dosage Forms

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 35-57
  5. Modified Release Solid Oral Dosage Forms

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 59-72
  6. Solution-Based Dosage Forms and Sterile Products

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 73-89
  7. Disperse Systems: Suspensions

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 91-110
  8. Disperse Systems: Emulsions

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 111-121
  9. Ophthalmic and Otic Drug Delivery

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 123-130
  10. Topical and Transdermal Drug Delivery

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 131-147
  11. Rectal and Vaginal Drug Delivery

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 149-161
  12. Pulmonary Drug Delivery

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 163-181
  13. Nasal Drug Delivery

    • Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III
    Pages 183-187
  14. Back Matter

    Pages 189-193

About this book

Particularly in healthcare fields, there is growing movement away from traditional lecture style course towards active learning and team-based activities to improve learning and build higher level thinking through application of complex problems with a strong foundation of facts and data. Essential Pharmaceutics is suited to this modern teaching style, and is the first book of its kind to provide the resources and skills needed for successful implementation of an active learning pharmaceutics course.This text offers a format that is specifically suited for integration in an active learning, team-based classroom setting. It is ideal for self-learning for the beginning pharmaceutics student, based upon the extensive utilization of figures, tables, and its overview of essential topics in pharmaceutics. Also unique to this text is the integration of case studies based upon modern pharmaceutical products which are designed to reinforce importance pharmaceutical concepts and teachessential skills in literature review and patent searching. Case studies covering all topics covered in the text have been developed by the authors that allow application of the content in the flipped-classroom pharmaceutical course.

Authors and Affiliations

  • College of Pharmacy, The University of Texas at Austin, Austin, USA

    Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III

About the authors

Ashlee D. Brunaugh is a registered pharmacist and Pharm.D. graduate from the University of Texas at Austin College of Pharmacy, where she is now a Ph.D. candidate within the Molecular Pharmaceutics and Drug Delivery Division. She has extensive teaching experience in a variety of Pharm.D. courses as well as multidisciplinary research experience in the pharmaceutical sciences, including protein characterization and formulation, small molecule formulation and characterization, and delivery device design. In 2019, she was awarded a Ruth L. Kirschstein National Research Service Award Predoctoral Fellowship from the National Heart, Lung and Blood Institute of the National Institutes of Health.  



Hugh D. C. Smyth is the Hamm Endowed Faculty Fellow and Professor of Pharmaceutics with Tenure, College of Pharmacy, The University of Texas at Austin. He is also an Adjunct Associate Scientist at the Lovelace Respiratory Research Institute, Albuquerque, NM. He is the Editor in Chief of Drug Development and Industrial Pharmacy. He has a Pharmacy and a Ph.D. degree from the University of Otago, New Zealand. He has been a faculty member at the University of North Carolina, Chapel Hill and at the University of New Mexico. He was the American Association of Pharmaceutical Scientists (AAPS) New Investigator award winner for Pharmaceutics and Pharmaceutical Technologies in 2007. He also received the PhRMA Foundation New Investigator Award in pharmaceutics in 2007. He has published over 250 peer-reviewed research articles, reviews, abstracts and book chapters, is the editor of 3 books, and has many patents and patent applications. He is the co-founder of several companies. His laboratory focuses on novel drug delivery systems. 




Bill Williams is the Johnson & Johnson Centennial Chair and Professor of Pharmaceutics and the Division Head of Molecular Pharmaceutics and Drug Delivery at the College of Pharmacy, University of Texas at Austin.  He earned a B.S. in Biology from Texas A&M University, a B.S. in Pharmacy from the University of Texas at Austin and Doctor of Philosophy in Pharmaceutics in 1986 from the University of Texas at Austin.  Dr. Williams worked 9 years in the pharmaceutical industry in the United States and France before returning to the University of Texas at Austin in 1995.  Dr Williams was elected a Fellow of the American Association of Pharmaceutical Scientists in 2006 and a Fellow of the American Institute of Medical and Biological Engineering in 2008.  He was named the Inventor of the Year by the University of Texas at Austin in 2017.  Dr. Williams is a member of the American Association of Pharmaceutical Scientists (AAPS) since its inception, as well as other professional societies including the American Association of Colleges of Pharmacy.  He is the co-founder of several pharmaceutical companies.  Dr. Williams’ research interests include development of novel drug delivery systems for oral, pulmonary, nasal, injectable, buccal and topical applications, development of novel particle engineering technologies for low molecular weight drugs, peptides and proteins, and analytical technologies to characterize actives, excipients and polymers.  He has published over 400 peer-reviewed research articles, reviews, abstracts and book chapters, and co-edited two books in the fields of pharmaceutical technology and drug delivery, including Formulating Poorly Water Soluble Drugs, Second Edition (AAPS and Springer). He is an inventor on over 35 patents and patent applications.  Dr. Williams served as Editor-in-Chief of the research journal Drug Development and Industrial Pharmacy from 2000 to 2014, and is the Editor-in-Chief of AAPS PharmSciTech since 2014.  He is on the Editorial Advisory Board of Journal of Drug Delivery Science and Technology, and he serves as a reviewer for numerous other journals.



Bibliographic Information

  • Book Title: Essential Pharmaceutics

  • Authors: Ashlee D. Brunaugh, Hugh D. C. Smyth, Robert O. Williams III

  • Series Title: AAPS Introductions in the Pharmaceutical Sciences

  • DOI: https://doi.org/10.1007/978-3-030-31745-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: American Association of Pharmaceutical Scientists 2019

  • Hardcover ISBN: 978-3-030-31744-7Published: 14 November 2019

  • Softcover ISBN: 978-3-030-31747-8Published: 14 November 2020

  • eBook ISBN: 978-3-030-31745-4Published: 05 November 2019

  • Series ISSN: 2522-834X

  • Series E-ISSN: 2522-8358

  • Edition Number: 1

  • Number of Pages: X, 193

  • Number of Illustrations: 9 b/w illustrations, 56 illustrations in colour

  • Topics: Pharmaceutical Sciences/Technology, Pharmacy

Buy it now

Buying options

eBook USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access