Musculoskeletal Tissue Regeneration

1. Front Matter

   Pages i-xxi

   PDF

2. Background

   1. Musculoskeletal and Wound Treatment Through the Ages: A Brief Historical Tour

      • William S. Pietrzak

      Pages 3-17

   2. Musculoskeletal Fundamentals: Form, Function, and a Survey of Healing Strategies

      • Wei Shen, Mario Ferretti, Mollie Manley, Freddie Fu

      Pages 19-38

   3. Overview of Fracture Repair

      • Bruce Doll, Matthew Aleef, Jeffrey O. Hollinger

      Pages 39-61

3. Hard Tissue Technologies

   1. Autograft Bone

      • Takaaki Fujishiro, Hideo Kobayashi, Thomas W. Bauer

      Pages 65-79

   2. Biology of Bone Allograft and Clinical Application

      • Victor M. Goldberg

      Pages 81-92

   3. Demineralized Bone Matrix: Maximizing New Bone Formation for Successful Bone Implantation

      • Lloyd Wolfinbarger Jr., Liisa M. Eisenlohr, Katrina Ruth

      Pages 93-117

   4. Deproteinized Bovine Bone Xenograft

      • Andreas Stavropoulos

      Pages 119-151

   5. Bioactive Bioceramics

      • Racquel Z. LeGeros, Guy Daculsi, John P. LeGeros

      Pages 153-181

   6. Distraction Osteogenesis of the Orthopedic Skeleton: Basic Principles and Clinical Applications

      • Mikhail L. Samchukov, Marina R. Makarov, Alexander M. Cherkashin, John G. Birch

      Pages 183-198

   7. Distraction Osteogenesis of the Facial Skeleton

      • Robert J. Havlik

      Pages 199-224

   8. Bone Morphogenetic Proteins and Other Bone Growth Factors

      • Barbara D. Boyan, Ramsey C. Kinney, Kimberly Singh, Joseph K. Williams, Yolanda Cillo, Zvi Schwartz

      Pages 225-245

   9. Biological Approaches to Spinal Fusion

      • Andrew K. Simpson, Peter G. Whang, Jonathan N. Grauer

      Pages 247-258

   10. Electrical Bone Stimulation

       • Josh Simon, Bruce Simon

       Pages 259-287

4. Soft Tissue Technologies

   1. Meniscus Repair Techniques

      • F. Alan Barber, Michael H. Boothby

      Pages 291-311

   2. Lessons Learned From Our First 100 Meniscus Allograft Transplants in Arthritic Knees

      • Kevin R. Stone, Ann W. Walgenbach, Abhi Freyer

      Pages 313-325

   3. Tissue Engineering of the Meniscus

      • Pieter Buma, Marloes van Meel, Tony G. van Tienen, Rene P.H. Veth

      Pages 327-346

   4. Osteochondral Grafts

      • Simon Görtz, Michael B. Boyd, William D. Bugbee

      Pages 347-368

   5. Autologous Chondrocyte Cartilage Repair

      • Stefan Marlovits

      Pages 369-394

   6. Autograft and Allograft ACL Reconstruction: Construct Rationale

      • Keith W. Lawhorn, Stephen M. Howell

      Pages 395-417

Tissue engineering and regenerative medicine will ultimately have a more profound impact than most of us can fully appreciate. The combination of the principles of engineering with advances in the material sciences, and an increased understanding of developmental biology has the potential to influence developments in medicine and biotechnology more than any single advance in these fields during the last several decades. I would first like to applaud the volume editor, Dr. Pietrzak, and the authors for their efforts in bringing together a group of interrelated topics to create a textbook emphasizing the Tissue Engineered generation of musculoskeletal tissue. The authors of this book are all established experts in their respective fields. The publication of a separate volume dedicated to musculoskeletal tissue regeneration as part of a series focusing on orthopedic biology and medicine is a reflection of the tremendous growth of knowledge and ongoing developments that have occurred in this field over the last decade. Musculoskeletal Tissue Regeneration: Biological Materials and Methods is intended to cover the basic fundamentals and early treatment of musculoskeletal disease, tissue loss and wound healing, as well as provide a comprehensive summary of recent advances in regenerative medicine and tissue engineering as they relate to the musculoskeletal system, and should serve as a reference for researchers and graduate students in this discipline.

• ACL Reconstruction
• Bioabsorbable Polymer
• Bone Allograft
• Bone Formation
• Bone Morphogenetic Protein
• Cartilage Regeneration
• Facial Skeleton
• Fracture Repair
• Gene Therapy
• Meniscal Repair
• Muscle Repair
• Musculoskeletal Tissue Banking
• Orthopedic Skele

From the reviews:

"This comprehensively edited text from experts in the area, covers both background information into the biology of musculoskeletal conditions and fracture repair, and techniques which may be used both for bone and soft tissue. … The text is well written and is certainly thought-provoking for people researching in this area, perhaps more so for musculoskeletal researchers than for practising clinicians. It should certainly occupy the shelves of libraries with vigorous academic departments." (Andrew Carr, Journal of Bone and Joint Surgery, June, 2009)

• Department of Bioengineering, University of Illinois at Chicago, Chicago, USA

  William S. Pietrzak

• Biomet, Inc., Warsaw, USA

  William S. Pietrzak

Policies and ethics