Skip to main content
SpringerLink
Log in

Chemokines in Disease

Biology and Clinical Research

  • Book
  • © 1999

Overview

Editors:
  1. Caroline A. Hébert

    1. Genentech, South San Francisco, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Contemporary Immunology (CONTIM)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xx
    Download chapter PDF

  2. Novel Chemokines Discovery and Genetically Engineered Mice

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. The Chemokine Gene Family

      • Vicki L. Schweickart, Carol J. Raport, David Chantry, Patrick W. Gray
      Pages 3-18

    3. Novel Chemokines Identified in Expressed Sequence Tag Databases via Bioinformatics

      • Kuldeep S. Neote, Shaun R. McColl
      Pages 19-39

    4. Understanding Chemokine Biology Through Mouse Genetics

      • Craig Gerard
      Pages 41-51

    5. MCP-1 in Human Disease

      • Landin Boring, Israel F. Charo, Barrett J. Rollins
      Pages 53-65

  3. Chemokines in Inflammatory Disease

    1. Front Matter

      Pages 67-67
      Download chapter PDF

    2. IL-8 in Animal Models of Disease

      • Akihisa Harada, Kouji Matsushima
      Pages 69-80

    3. The Role of Chemokines in the Pathophysiology of the Acute Respiratory Distress Syndrome (ARDS)

      • Thomas R. Martin, Richard B. Goodman
      Pages 81-110

    4. The Role of Chemokines in Allergic Airway Inflammation

      • Nicholas W. Lukacs
      Pages 111-121

    5. Eotaxin in Disease

      • Dolores M. Conroy, Timothy J. Williams
      Pages 123-138

    6. The Role of CC Chemokines in Th1- and Th2-Type Pulmonary Inflammation Models

      • Cory M. Hogaboam, Stephen W. Chensue, Steven L. Kunkel
      Pages 139-149

    7. Chemokines in Rheumatoid Arthritis

      • Christine Plater-Zyberk, Jiri Vencovsky, Christine A. Power
      Pages 151-158

    8. Potential Roles for Chemokines in Transplant Rejection

      • Ronald P. Gladue, Thomas M. Coffman
      Pages 159-168

  4. Chemokines in Tumor Biology

    1. Front Matter

      Pages 169-169
      Download chapter PDF

    2. The Role of CXC Chemokines in the Regulation of Angiogenesis in Association with Non-Small-Cell Lung Cancer

      • Robert M. Strieter, Christina L. Addison, Bethany B. Moore, Douglas A. Arenberg
      Pages 171-189

    3. The Role of ELR+-CXC Chemokines in Wound Healing and Melanoma Biology

      • Ann Richmond, Jing Luan, Jianguo Du, Hamid Haghnegahdar
      Pages 191-214

    4. Engineering, Biology, and Clinical Development of hMIP-1α

      • Lloyd G. Czaplewski, Matthew McCourt, Michael G. Hunter, Brian I. Lord, Andy Millar, L. Mike Wood
      Pages 215-232

  5. Chemokines in Viral Biology

    1. Front Matter

      Pages 233-233
      Download chapter PDF

    2. Viral Mimicry of Chemokines and Chemokine Receptors

      • Sunil K. Ahuja, Philip M. Murphy
      Pages 235-251
Back to top

Keywords

About this book

Caroline Hébert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology. The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments. Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory processes. A detailed review of the emerging role of chemokines in viral biology is also presented, with emphasis on HIV biology and novel therapeutic possibilities. Chemokines in Disease: Biology and Clinical Research summarizes the rapidly expanding knowledge of a dazzling array of chemokines and provides fresh insights into the development of powerful new drugs for treating a wide spectrum of diseases.

Reviews

". . . contains a masterful review of some of the most exciting areas in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to angiogenesis/antiangiogenesis, to inflammation, to asthma, to transplantation, to name a few of the areas of study. :-Foreword by Peter Ward, PhD
.
"The editor is a recognized authority in chemokines. Knowledgeable individuals wrote the chapters. . .There is, in this one volume, a major focus on different diseases in which chemokines seem to play particularly important roles and thus the information is easily accessed. "-Doody's Health Scienc Book Review Journal

"...the reader will find great interest in reading the very good reviews on the contribution of chemokines in inflammatory diseases....A very nicely documented chapter deals with the presence of chemokine receptors in the central nervous system (CNS) and illustrates the importance to further study this field during CNS related diseases such as Alzheimer's disease or multiple sclerosis....very interesting and important topics are presented in this book.... All scientists and physicians dealing with inflammatory processes should be aware of its content."- Biochimie

Editors and Affiliations

  • Genentech, South San Francisco, USA

    Caroline A. Hébert

Bibliographic Information

  • Book Title: Chemokines in Disease

  • Book Subtitle: Biology and Clinical Research

  • Editors: Caroline A. Hébert

  • Series Title: Contemporary Immunology

  • DOI: https://doi.org/10.1007/978-1-59259-706-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1999

  • Hardcover ISBN: 978-0-89603-703-8Published: 01 June 1999

  • Softcover ISBN: 978-1-4757-4762-1Published: 24 March 2013

  • eBook ISBN: 978-1-59259-706-2Published: 01 June 1999

  • Edition Number: 1

  • Number of Pages: XX, 330

  • Number of Illustrations: 12 b/w illustrations, 8 illustrations in colour

  • Topics: Immunology

Publish with us

Policies and ethics

Back to top

Search

Navigation