Studies on Atherosclerosis

1. Front Matter

   Pages i-xv

   PDF

2. Oxidative Stress in Cardiac Valve Development

   • Danielle Huk, Joy Lincoln

   Pages 1-18

3. ROS in Atherosclerotic Renovascular Disease

   • Xiang-Yang Zhu, Lilach O. Lerman

   Pages 19-45

4. Oxidative Stress and Vascular Injury

   • Akshaar Brahmbhatt, Sanjay Misra

   Pages 47-57

5. Role of Oxidative Stress in Hypertension

   • Sophocles Chrissobolis, Quynh N. Dinh, Grant R. Drummond, Christopher G. Sobey

   Pages 59-78

6. Oxidative Stress and Central Regulation of Blood Pressure

   • Yoshitaka Hirooka, Kenji Sunagawa

   Pages 79-87

7. Reactive Oxygen Species and the Regulation of Cerebral Vascular Tone

   • T. Michael De Silva, Frank M. Faraci

   Pages 89-112

8. Therapeutic Strategies Harnessing Oxidative Stress to Treat Stroke

   • Gina Hadley, Ain A. Neuhaus, Alastair M. Buchan

   Pages 113-133

9. Back Matter

   Pages 135-138

   PDF

This volume explores the role free radicals and antioxidants within the development of vascular disease, examining fundamental research and translating preclinical knowledge to clinical trials. The expertly authored chapters describe the relationship of oxidative stress to atherosclerosis and the cardiovascular system, exploring its role in cardiac fibrosis, renovascular disease, hypertension, and regulation of blood pressure and cerebral vascular tone. The concluding chapter discusses the current state of clinical research, contextualizing clinical trials within the existing theoretical framework and analyzing attempts to preserve oxidant stress under various conditions. 


With its concise and authoritative analysis of pre-clinical research and clinical results, Studies in Atherosclerosis – part of the bestselling Oxidative Stress in Basic Research and Clinical Practice series – is essential for researchers and clinicians focusing in cardiology, nephrology, or oxidative stress.

• antioxidant
• atherosclerotic plaque
• cardiovascular disease
• myocardium
• reactive oxygen species

• Cardiovascular Diseases, Mayo Clinic, Rochester, USA

  Martin Rodriguez-Porcel

• University of Mississippi, Jackson, USA

  Alejandro R. Chade

• Department of Surgery, Mayo Clinic, Rochester, USA

  Jordan D. Miller

Policies and ethics