Skip to main content
SpringerLink
Log in

Longevity Genes

A Blueprint for Aging

  • Book
  • © 2015

Overview

Editors:
  1. Gil Atzmon, PhD

    1. Albert Einstein College of Medicine, Bronx, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Discusses innovative ways to use whole genome sequencing tools in the study of aging
  • Introduces readers to bio-statistical approaches to deal with the complex data set generated by whole genome sequencing when studying aging
  • Covers the whole palette of genetic component studies in order to expose readers to the major research efforts associated with aging today
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 847)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (9 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Evolutionary Genetic Bases of Longevity and Senescence

    • Diddahally R. Govindaraju
    Pages 1-44

  3. Candidate Genes That Affect Aging Through Protein Homeostasis

    • Yair Argon, Tali Gidalevitz
    Pages 45-72

  4. Autophagy and Aging

    • Nuria Martinez-Lopez, Diana Athonvarangkul, Rajat Singh
    Pages 73-87

  5. A Genetic View of the Mitochondrial Role in Ageing: Killing Us Softly

    • Liron Levin, Dan Mishmar
    Pages 89-106

  6. GWAS and Meta-Analysis in Aging/Longevity

    • Linda Broer, Cornelia M. van Duijn
    Pages 107-125

  7. Exome and Whole Genome Sequencing in Aging and Longevity

    • Erik B. van den Akker, Joris Deelen, P. Eline Slagboom, Marian Beekman
    Pages 127-139

  8. Models to Explore Genetics of Human Aging

    • David Karasik, Anne Newman
    Pages 141-161

  9. Systems Biology of Aging

    • Kendra Bolt, Aviv Bergman
    Pages 163-178

  10. Epigenetics of Aging

    • Dan Ben-Avraham
    Pages 179-191

  11. Back Matter

    Pages 193-194
    Download chapter PDF
Back to top

Keywords

About this book

The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.

Editors and Affiliations

  • Albert Einstein College of Medicine, Bronx, USA

    Gil Atzmon, PhD

Bibliographic Information

  • Book Title: Longevity Genes

  • Book Subtitle: A Blueprint for Aging

  • Editors: Gil Atzmon, PhD

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4939-2404-2

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2015

  • Hardcover ISBN: 978-1-4939-2403-5Published: 27 April 2015

  • Softcover ISBN: 978-1-4939-5555-8Published: 05 October 2016

  • eBook ISBN: 978-1-4939-2404-2Published: 27 April 2015

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 194

  • Number of Illustrations: 2 b/w illustrations, 16 illustrations in colour

  • Topics: Human Genetics, Bioinformatics, Systems Biology

Publish with us

Policies and ethics

Back to top

Search

Navigation