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Topical Drug Bioavailability, Bioequivalence, and Penetration

Editors: Shah, Vinod, Maibach, Howard I., Jenner, John (Eds.)

  • Examines the techniques used to measure percutaneous penetration of drugs and chemicals that have found application in assessment of bioavailability and bioequivalence
  • Discusses advances in drug delivery and how they have been used in clinical and scientific investigations
  • Brings the most current knowledge in this area to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds
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eBook 118,99 €
price for Spain (gross)
  • ISBN 978-1-4939-1289-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 155,99 €
price for Spain (gross)
valid through October 16, 2017
  • ISBN 978-1-4939-1288-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 155,99 €
price for Spain (gross)
  • ISBN 978-1-4939-3856-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations.  Seven comprehensive sections examine topics including in vitro drug release, topical drugs products, clinical studies, and guidelines and workshop reports, among others. The book also describes how targeted transdermal drug delivery and more sophisticated mathematical modelling can aid in understanding the bioavailability of transdermal drugs.

 The first edition of this book was an important reference guide for researchers working to define the effectiveness and safety of drugs and chemicals that penetrated the skin. This second edition contains cutting-edge advances in the field and is a key resource to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds to improve scientific and clinical investigation and regulation.

About the authors

Vinod P. Shah is a pharmaceutical consultant. He was Scientific Secretary of International Pharmaceutical Federation (FIP) and is now Chair of Regulatory Sciences Special Interest Group of FIP. Dr. Shah has served at the U.S. Food and Drug Administration and has developed several regulatory guidances for the pharmaceutical industry in biopharmaceutics and topical drug products. Dr. Shah is a fellow of FIP as well as the American Association of Pharmaceutical Scientists (AAPS), where he served as president for a year. He is a recipient of an honorary doctorate from Semmelweis University, Budapest, Hungary.  

Howard I. Maibach is professor of dermatology at the University of California, San Francisco. He received his M.D. at Tulane University Medical School in New Orleans, Louisiana, and completed his residency and research fellowships at the University of Pennsylvania in Philadelphia, Pennsylvania. Professor Maibach is a leading authority in the fields of dermatotoxicology and dermatopharmacology, in which he has conducted research and written extensively. Prof. Maibach has served on the editorial boards of more than thirty scientific journals and is a member of many professional societies, including the American Academy of Dermatology and the International Commission on Occupational Health.

John Jenner is a principal scientist at The Defence Science and Technology Laboratory in the UK. He has a degree in pharmacology from the University of Manchester in Manchester, UK, and a Ph.D. from the University of Surrey, Guildford, UK. John has spent his career studying defense against and treatment of highly toxic chemicals. He has an enduring research interest in percutaneously active chemicals, whether toxic materials or drugs, and experience in the design and testing of transdermal formulations. His current interests include the translation of in vitro penetration measurements to in vivo using mathematical modelling.

Table of contents (23 chapters)

  • Percutaneous Absorption

    Leo, Michael S. (et al.)

    Pages 3-19

    Preview Buy Chapter 30,19 €
  • Animal Models for Percutaneous Absorption

    Jung, Eui Chang (et al.)

    Pages 21-40

    Preview Buy Chapter 30,19 €
  • Mitigating Dermal Exposure to Agrochemicals

    Chilcott, Robert P.

    Pages 41-57

    Preview Buy Chapter 30,19 €
  • Importance of In Vitro Drug Release

    Shah, Vinod P. (et al.)

    Pages 61-67

    Preview Buy Chapter 30,19 €
  • Diffusion Cell Design

    Heylings, Jon R.

    Pages 69-80

    Preview Buy Chapter 30,19 €

Buy this book

eBook 118,99 €
price for Spain (gross)
  • ISBN 978-1-4939-1289-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 155,99 €
price for Spain (gross)
valid through October 16, 2017
  • ISBN 978-1-4939-1288-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 155,99 €
price for Spain (gross)
  • ISBN 978-1-4939-3856-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Topical Drug Bioavailability, Bioequivalence, and Penetration
Editors
  • Vinod Shah
  • Howard I. Maibach
  • John Jenner
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-1289-6
DOI
10.1007/978-1-4939-1289-6
Hardcover ISBN
978-1-4939-1288-9
Softcover ISBN
978-1-4939-3856-8
Edition Number
2
Number of Pages
XIII, 402
Number of Illustrations and Tables
48 b/w illustrations, 16 illustrations in colour
Topics