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  • © 2014

Cholesterol Transporters of the START Domain Protein Family in Health and Disease

START Proteins - Structure and Function

  • Focuses on Star function in non-steroidogenic tissues

  • Addresses the emerging possibilities for STARD4 and STARD5 in cholesterol homeostasis and dysregulation

  • Provides perspective to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process

  • Includes supplementary material: sn.pub/extras

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eBook USD 84.99
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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xiv
  2. The Steroidogenic Acute Regulatory Protein (StAR)

    • Barbara J. Clark, Douglas M. Stocco
    Pages 15-47
  3. START Domain Protein Structure and Ligand Specificity

    • Danny Létourneau, Pierre Lavigne, Andrée Lefebvre, Jean-Guy LeHoux
    Pages 49-72
  4. Congenital Lipoid Adrenal Hyperplasia

    • Walter L. Miller
    Pages 73-97
  5. Steroidogenic Acute Regulatory Protein (StAR) and Atherogenesis

    • Annette Graham, Faye Borthwick, Janice Taylor
    Pages 99-117
  6. STARD3: A Lipid Transfer Protein in Breast Cancer and Cholesterol Trafficking

    • Fabien Alpy, Catherine L. Tomasetto
    Pages 119-138
  7. Back Matter

    Pages 189-190

About this book

Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer and atherogenesis.

This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process.

Editors and Affiliations

  • Biochemistry and Molecular Biology, University of Louisville School of Medicine, Louisville, USA

    Barbara J. Clark

  • Cell Biology and Biochemistry, Texas Tech Univ. Health Sciences Center, Lubbock, USA

    Douglas M. Stocco

Bibliographic Information

  • Book Title: Cholesterol Transporters of the START Domain Protein Family in Health and Disease

  • Book Subtitle: START Proteins - Structure and Function

  • Editors: Barbara J. Clark, Douglas M. Stocco

  • DOI: https://doi.org/10.1007/978-1-4939-1112-7

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4939-1111-0Published: 24 July 2014

  • Softcover ISBN: 978-1-4939-5403-2Published: 03 September 2016

  • eBook ISBN: 978-1-4939-1112-7Published: 24 July 2014

  • Edition Number: 1

  • Number of Pages: XIV, 190

  • Number of Illustrations: 4 b/w illustrations, 21 illustrations in colour

  • Topics: Endocrinology, Protein Science, Biomedicine general

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access