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Advances in Biochemistry in Health and Disease

Phospholipases in Health and Disease

Editors: Tappia, Paramjit S, Dhalla, Naranjan S. (Eds.)

  • Focuses on the role of phospholipases in cellular function in health and disease
  • Includes up-to-date knowledge about these enzymes and related signal transduction mechanisms
  • Provides a comprehensive discussion on three different types of phospholipases in the same volume
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eBook 154,69 €
price for Spain (gross)
  • ISBN 978-1-4939-0464-8
  • Digitally watermarked, DRM-free
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 192,39 €
price for Spain (gross)
valid through October 16, 2017
  • ISBN 978-1-4939-0463-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 192,39 €
price for Spain (gross)
  • ISBN 978-1-4939-4639-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
About this book

Phospholipases generate lipid signaling molecules through their hydrolytic action on phospholipids and are known to regulate function of a variety of cells under normal and diseased conditions. While several physiological, biochemical and molecular techniques have identified key players involved in different disease processes, phospholipases have also emerged as critical players in the pathogenesis of a number of different diseases including cancer and heart disease. In addition, phospholipases are also implicated in such conditions as brain disorder/injury, kidney and immune cell dysfunction.

Phospholipases in Health and Disease is a compilation of review articles dedicated to the study of the field with respect to biochemical and molecular mechanisms of normal and abnormal cell function. The wide range of area covered here is of interest to basic research scientists, clinicians and graduate students, who are engaged in studying pathophysiological basis of a variety of diseases. Furthermore, this book highlights the potential of the different phospholipases as therapeutic targets as well as part of prevention strategies. Twenty three articles in this book are organized in four sections that are designed to emphasize the most characterized forms of the phospholipases in mammalian cells. The first section discusses general aspect of phospholipases. Section two covers the role and function of phospholipase A in different pathophysiological conditions. The third section is focussed on phospholipase C which is believed to play a central role in transmembrane signaling. The final section covers phospholipase D which is present in a variety of different cells. The book illustrates that the activation of phospholipases is of fundamental importance in signal transduction affecting cell function. Overall, this book discusses the diverse mechanisms of phospholipase mediated signal transduction in different pathophysiological conditions and raises the possibility of specific forms of phospholipases serving as novel targets for drug development.

Table of contents (23 chapters)

  • Phospholipases in Health and Disease

    Yang, Yong Ryoul (et al.)

    Pages 3-38

    Preview Buy Chapter 30,19 €
  • Role of Phospholipases in Regulation of Cardiolipin Biosynthesis and Remodeling in the Heart and Mammalian Cells

    Mejia, Edgard M. (et al.)

    Pages 39-53

    Preview Buy Chapter 30,19 €
  • Role of Phospholipases and Oxidized Phospholipids in Inflammation

    Hasanally, Devin (et al.)

    Pages 55-72

    Preview Buy Chapter 30,19 €
  • Phospholipases in Cardiovascular Disease

    Ikonomidis, Ignatios (et al.)

    Pages 73-83

    Preview Buy Chapter 30,19 €
  • The Structures and Functions of Intracellular Phospholipase A1 Family Proteins

    Tani, Katsuko (et al.)

    Pages 87-99

    Preview Buy Chapter 30,19 €

Buy this book

eBook 154,69 €
price for Spain (gross)
  • ISBN 978-1-4939-0464-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 192,39 €
price for Spain (gross)
valid through October 16, 2017
  • ISBN 978-1-4939-0463-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
Softcover 192,39 €
price for Spain (gross)
  • ISBN 978-1-4939-4639-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
  • The final prices may differ from the prices shown due to specifics of VAT rules
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Bibliographic Information

Bibliographic Information
Book Title
Phospholipases in Health and Disease
Editors
  • Paramjit S Tappia
  • Naranjan S. Dhalla
Series Title
Advances in Biochemistry in Health and Disease
Series Volume
10
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4939-0464-8
DOI
10.1007/978-1-4939-0464-8
Hardcover ISBN
978-1-4939-0463-1
Softcover ISBN
978-1-4939-4639-6
Edition Number
1
Number of Pages
XIX, 410
Number of Illustrations and Tables
16 b/w illustrations, 53 illustrations in colour
Topics