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Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

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  • © 2013

Overview

  • Provides a comprehensive overview on neuroimmune mechanisms mediating changes in brain function and behavior associated with alcohol drinking
  • Combines emerging knowledge on neural-immune interactions with key discoveries in alcohol research
  • First book to focus on the the interactions between alcohol and the neuroimmune system
  • Includes supplementary material: sn.pub/extras

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Table of contents (18 chapters)

  1. Neural–Immune Interactions

  2. Neural-immune Interactions

  3. Alcohol and Neuroimmune Interactions

Keywords

About this book

Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders.  These advances have a far reaching impact on many areas of neuroscience, including alcohol research.  Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.

Editors and Affiliations

  • National Institute on Alcohol Abuse and, Division of Neuroscience and Behavior, NIH, Bethesda, USA

    Changhai Cui, Lindsey Grandison, Antonio Noronha

Bibliographic Information

  • Book Title: Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

  • Editors: Changhai Cui, Lindsey Grandison, Antonio Noronha

  • DOI: https://doi.org/10.1007/978-1-4614-4729-0

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2013

  • Hardcover ISBN: 978-1-4614-4728-3Published: 25 October 2012

  • Softcover ISBN: 978-1-4899-9578-0Published: 09 November 2014

  • eBook ISBN: 978-1-4614-4729-0Published: 14 November 2012

  • Edition Number: 1

  • Number of Pages: VIII, 588

  • Topics: Neurosciences, Neurochemistry, Immunology

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