Molecular Basis of Human Blood Group Antigens

1. Front Matter

   Pages i-xx

   PDF

2. Red Cell Membrane

   • Jean Delaunay

   Pages 1-36

3. ABO, Hh, Lewis, and Secretion

   • Rafael Oriol

   Pages 37-73

4. Biochemistry and Biosynthesis of ABH and Lewis Antigens

   • John B. Lowe

   Pages 75-115

5. Serology, Biochemistry, and Pathology of Antigens Defined by Cold Agglutinins

   • Dieter Roelcke

   Pages 117-152

6. MNSs Blood Groups and Major Glycophorins

   • Cheng-Han Huang, Olga O. Blumenfeld

   Pages 153-188

7. RH Blood Groups and Rh-Deficiency Syndrome

   • Jean-Pierre Cartron, Peter Agre

   Pages 189-225

8. Kell Blood Group System and the McLeod Syndrome

   • Colvin M. Redman, Soohee Lee

   Pages 227-242

9. The Duffy Blood Group System and Malaria

   • Asok Chaudhuri, A. Oscar Pogo

   Pages 243-265

10. The Kidd Blood Group and Urea Transport

    • Joann M. Moulds

    Pages 267-279

11. Lutheran Antigens, Lutheran Regulatory Genes, and Lutheran Regulatory Gene Targets

    • Neeraja Rao, Marilyn J. Telen

    Pages 281-297

12. P Blood Group and Related Antigens

    • Pascal Bailly, Jean-François Bouhours

    Pages 299-329

13. Gerbich Blood Groups and Minor Glycophorins

    • Yves Colin, Caroline Le Van Kim

    Pages 331-350

14. Sda and Cad Antigens

    • Winifred M. Watkins

    Pages 351-375

15. Overview of Other Blood Group Systems

    • Patricia Tippett

    Pages 377-395

16. Blood Group Antigens as Markers of Complement and Complement Regulatory Molecules

    • Geoff Daniels

    Pages 397-419

17. Histo-Blood Group Antigens as Tumor-Associated Carbohydrate Antigens and Ligands for Cell Adhesion

    • Sen-itiroh Hakomori

    Pages 421-443

18. Linkage Relationships and Gene Mapping of Human Blood Group Loci

    • Marion Lewis, Teresa Zelinski

    Pages 445-475

19. Nomenclature of Blood Group Antigens

    • Pierre-Yves Le Pennec, Philippe Rouger

    Pages 477-486

20. Back Matter

    Pages 487-492

    PDF

The science of blood groups was born at the beginning of this century, when the field of immunology married that of genetics. Most of the subsequent progress in immunogenetics was achieved by British investigators. The six consecutive editions of the unequaled Blood Groups in Man have long been considered as the bible of blood groupers. It is quite unfortunate that this book has not been revisited since 1975. Although one cannot do without immunogenetics, which remains useful for the identification of new blood groups and genetic studies, the focus of interest has moved somewhat today. After several decades, the molecular basis of blood groups can be investigated by biochemists. From 1950 to 1980, the ABO, Hh, and Lewis blood groups served as models and their chemical basis came to be established. The red cell membrane glycophorins carrying the MN and Ss antigens and the glycolipids with P blood group specificities were also identified and characterized. The chemical basis of the other groups, however, remained largely unknown.

• Antigen
• biochemistry
• biology
• blood
• cell
• cell membrane
• genetics
• molecular biology
• parasite
• pathology
• protein
• proteins
• receptor
• synthesis
• tissue

`This significant and valuable book is a volume of a great series....All contributors are strongly involved experts and leading authorities in their field....Highly useful for all clinicians and researchers.'
International Journal of Hematology

`Provide[s] a comprehensive account of the biology of blood cells....a valuable overview of the subject...A strong case can be made for the purchase of the series by appropriate libraries.'
Trends in Biological Sciences, from a review of a previous volume

• National Institute of Blood Transfusion, Paris, France

  Jean-Pierre Cartron, Philippe Rouger

Policies and ethics