Regulation of Leukocyte Function

1. Front Matter

   Pages i-xix

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2. Transductional Mechanisms of Chemoattractant Receptors on Leukocytes

   • Ralph Snyderman, Marilyn C. Pike

   Pages 1-28

3. The Neutrophil N-Formyl Peptide Receptor: Dynamics of Ligand-Receptor Interactions and Their Relationship to Cellular Responses

   • Larry A. Sklar, Algirdas J. Jesaitis, Richard G. Painter

   Pages 29-82

4. Neutrophil Chemoattractant fMet-Leu-Phe Receptor Expression and Ionic Events Following Activation

   • John I. Gallin, Bruce E. Seligmann

   Pages 83-108

5. Mechanisms of Leukocyte Regulation by Complement-Derived Factors

   • Tony E. Hugli, Edward L. Morgan

   Pages 109-153

6. Regulation of Human Leukocyte Function by Lipoxygenase Products of Arachidonic Acid

   • Frank H. Valone

   Pages 155-170

7. Structure and Modulation of Fc and Complement Receptors

   • Jay C. Unkeless, Samuel D. Wright

   Pages 171-187

8. Neutrophil Degranulation

   • Ira M. Goldstein

   Pages 189-219

9. Exocytosis by Neutrophils

   • Marco Baggiolini, Beatrice Dewald

   Pages 221-246

10. Mechanisms of Regulating the Respiratory Burst in Leukocytes

    • Linda C. McPhail, Ralph Snyderman

    Pages 247-281

11. Nonoxidative Antimicrobial Reactions of Leukocytes

    • John K. Spitznagel

    Pages 283-343

12. Clinical Disorders of Leukocyte Functions

    • Harry R. Hill

    Pages 345-393

13. Addendum to Chapter 2

    • Ralph Snyderman

    Pages 395-396

14. Back Matter

    Pages 397-410

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There was a time, not all that long ago, when scientific study of the cell was called cytology, and the workers in the field named themselves cytologists. When I was a medical student, lectures in cytology were a special, segregated part of the curriculum in the histology course, given along with general anatomy, and they were, as I recall, the surest of cures for insomnia. I still possess Cowdry's three-volume set entitled Special Cytology, published in 1934, and leafing through these books today is rather like examining a medieval manuscript. You could never have guessed what was going to happen to the field. At that time it was all structure, and all guesswork about the structure. When cells were packed together in various tissues, how did the geometry of packing work? How many sides did a liver cell have, in real life? What on earth were all those granules in­ side, and what were the best stains for looking at them? One thing about those granules, they never moved. Indeed, nothing moved. Cytology turned into cell biology much later on, and suddenly came alive. As has been the case in so many diSciplines in biology, it was brought to life by techniques. New instruments and cytochemical methods were devised for look­ ing at cells, manipulating cells, more or less in vivo.

• Insomnia
• anatomy
• antimicrobial
• biology
• cell
• cell biology
• cells
• cytology
• histology
• leukocyte
• liver
• regulation
• tissue
• infectious diseases

• Howard Hughes Medical Institute, Duke University Medical Center, Durham, USA

  Ralph Snyderman

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