Applied Bioactive Polymeric Materials

1. Front Matter

   Pages i-x

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2. Overview of Synthetic and Modified Natural Bioactive Polymers

   • Charles G. Gebelein, Charles E. Carraher Jr., Van R. Foster

   Pages 1-15

3. Pesticide-Polymer Research: A Review of 1976–87

   • David A. Kurtz, Kevin Hassett

   Pages 17-43

4. Chitosan and Derivatives as Activators of Plant Cells in Tissues and Seeds

   • Shigehiro Hirano, Masahiko Hayashi, Kakuko Murae, Hisaya Tsuchida, Takeshi Nishida

   Pages 45-59

5. Biodegradation of Hydroxylated Polymers

   • Laura J. DiBenedetto, J. A. Cameron, Samuel J. Huang

   Pages 61-74

6. Combined Matrix Concept in Delivery of Bioactive Polypeptides

   • Paul Y. Wang, Evelyn Kothe

   Pages 75-84

7. Metal-Promoted Hydrolysis of Polymeric Chelating Agents: Chelators on Demand

   • C. G. Pitt, Z.-W. Gu, J.-H. Zhu, Y. T. Bao

   Pages 85-90

8. Formation of Polymeric Antimicrobial Surfaces from Organofunctional Silanes

   • R. L. Gettings, W. C. White

   Pages 91-95

9. Development of Polymers with Anti-Infectious Properties

   • B. Jansen, G. Peters, S. Schareina, H. Steinhauser, F. Schumacher-Perdreau, G. Pulverer

   Pages 97-113

10. Synthesis and Characterization of Polymers Having Steroid Sex Hormones as Pendent Moieties

    • Malay Ghosh

    Pages 115-123

11. Novel Approaches and Applications of Steroid Hormone Delivery Via Poly(Dimethylsiloxane)

    • D. J. Kesler

    Pages 125-137

12. Kinetics of Synthesis and Degradation of the Polymer Derived from Tetrachloroplatinate and Methotrexate

    • Charles E. Carraher Jr., Rickey E. Strothers

    Pages 139-150

13. The Release of 5-Fluorouracil from Polycaprolactone Matrices

    • Charles G. Gebelein, Mark Chapman, Tahseen Mirza

    Pages 151-163

14. Synthesis of Antitumor Polysaccharides

    • Kei Matsuzaki, Iwao Yamamoto, Koji Enomoto, Yutaro Kaneko, Tohru Mimura, Tsuyoshi Shiio

    Pages 165-174

15. Biological Activities of Tin-Containing Saccharides and Polysaccharides

    • Charles E. Carraher Jr., Cynthia Butler, Yoshinobu Naoshima, Van R. Foster, David Giron, Philip D. Mykytiuk

    Pages 175-183

16. Nucleic Acid Analogs for High Performance Liquid Chromatography

    • Yoshiaki Inaki, Suguru Nagae, Takashi Miyamoto, Yoshihiko Sugiura, Kiichi Takemoto

    Pages 185-204

17. Immune Modulating Effects of Poly(ICLC) in Mice, Monkeys and Man

    • Hilton B. Levy, Christopher Bever Jr.

    Pages 205-221

18. Effect of Tetramisole and Its Platinum Polyamine on Mice Infected with Encephalomyocarditis-Variant-D Virus

    • Mary Trombley, Nancy J. Biegley, Charles E. Carraher Jr., David J. Giron

    Pages 223-238

19. Influence of Short Chain Phospholipid Spacers on the Properties of Diacetylenic Phosphatidylcholine Bilayers

    • Alok Singh, Bruce P. Gaber

    Pages 239-249

20. Graft Copolymers of Amino Acids onto Natural and Synthetic Polymers

    • William H. Daly, Soo Lee

    Pages 251-274

The biological and biomedical applications of polymeric materials have increased greatly in the past few years. This book will detail some, but not all, of these recent developments. There would not be enough space in this book to cover, even lightly, all of the major advances that have occurred. Some earlier books and summaries are available by two of this book's Editors (Gebelein & Carraher) and these should be consul ted for additional information. The books are: "Bioactive Polymeric Systems" (Plenum, 1985); "Polymeric Materials In Medication" (Plenum, 1985); "Biological Acti vi ties of Polymers" (American Chemical Society, 1982). Of these three, "Bioacti ve Polymeric Systems" should be the most useful to a person who is new to this field because it only contains review articles written at an introductory level. The present book primarily consists of recent research results and applications, with only a few review or summary articles. Bioactive polymeric materials have existed from the creation of life itself. Many firmly believe that life could not even exist unless poly­ meric materials are used to form the basic building blocks. Although this assumption can not be rigorously proven, it is a fact that most, if not all, of the major biochemical pathways involve polymeric species, such as the proteins (including enzymes), polysaccharides and nucleic acids.

• Copolymer
• Polycaprolacton
• Polyvinylpyrrolidon
• biodegradation
• biomedical applications
• development
• enzyme
• enzymes
• information
• nucleic acid
• nucleic acids
• polymer
• protein
• proteins
• society

• Youngstown State University, Youngstown, USA

  Charles G. Gebelein

• Florida Atlantic University, Boca Raton, USA

  Charles E. Carraher

• DAP, Inc., Dayton, USA

  Van R. Foster

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